Scientists crafted glow-in-the-dark #succulents that recharge in sunlight. Injected with light-emitting phosphor, the plants can shine as bright as a small night light. cell.com/matter/fullt...

@cp-matter.bsky.social
#SCAU Shuting Liu & colleagues

Graphic shows a map of the U.S. that is color-coded by the percentage of kindergartners not up to date on measles vaccines. Among the worst states are Idaho (20%), Alaska (16%) and Colorado (11.1%). Among the states with the lowest number of unvaccinated kids are Mississippi (2.5%) and West Virginia (1.7%).

Which states have the most kids not getting vaccinated? ID (20%), AK (15%), and WI (15%). The states with highest vaccine coverage include WV, CA, NY and MS.
parequirements.com/img/blog/mea...

Meet the Dougherty Plain Cave Crayfish (Cambarus cryptodytes), an underground species endemic to Florida and Georgia. 🧵⤵️

📷 hydrophilus on iNaturalist
📍 United States
🔗: www.inaturalist.org/observations...
#ObservationOfTheDay

Interested in synthetic approaches to both understand and manipulate gene expression? We (the Bintu lab) wrote a review that discusses just that - how modern low- and high-throughput approaches can dissect gene regulation at the DNA, RNA, and protein level. www.annualreviews.org/content/jour...

They should lose their accreditation; all the schools that do this should. I’m sorry, it’s time to be brutal. Like Republicans. (NB: this has nothing to do w/ the fact that it would be a thing of the purest beauty to start w/ #OSU, but I fully support the same for my superior alma mater, #Michigan.)

four images of the front, top, and side a small globular frog with large black and alien-like eyes, smooth purple-brown body in the shape of a turtle

Shout out to the Turtle Frog, Myobatrachus gouldii, from Australia. Image from Vertucci et al. 2017 journals.plos.org/plosone/arti... 🌿🐸🧪

Thank you to the #Cancer Straight Talk podcast through @mskcancercenter.bsky.social for bringing my attention to this useful database on herbs and other dietary supplements.
www.mskcc.org/cancer-care/...

The number of ways to activate the immune system attack vs cancer keeps increasing. Here, using bacteria to amp up the response to wild tumor, the mechanism via a surge of interleukin-10 is elucidated
www.cell.com/cell/fulltex... @cellpress.bsky.social open-access

Gut microbiota-derived hexa-acylated lipopolysaccharides enhance cancer immunotherapy responses Nature Microbiology - Hexa-acylated lipopolysaccharides from the gut microbiota are associated with efficacy in patients with cancer receiving anti-PD-1 and stimulate host immune activation for...

Gut microbiome composition may predict ICI response in patients with melanoma or renal cell carcinoma. Interesting work from this group out of Cambridge in collaboration with @mskcancercenter.bsky.social
rdcu.be/eb2YL

No evidence for Peto’s paradox in terrestrial vertebrates | PNAS Larger, longer-lived species are expected to have a higher cancer prevalence compared to smaller, shorter-lived species owing to the greater number...

New evidence in this 48-year-old paradox. A finding in S4B seems to show that the longer mammals live, the less likely they are to experience neoplasia. The mechanism may be similar to r/K selection, not just parents are invested in longevity, it's encoded in the genome.
www.pnas.org/doi/10.1073/...

You’ve Heard Of The Microbiome—Welcome To The Mycobiome Though fungi make up a tiny part of the human microbiome, they play an important role in both the prevention and development of many diseases.

Though fungi make up a tiny part of the human microbiome, they play an important role in disease prevention and development.

Dr. Mahmoud Ghannoum joins us to discuss what scientists are learning about the “mycobiome.”

Intrinsic electrical activity drives small-cell lung cancer progression - Nature Electrical excitability in neuroendocrine SCLC cells promotes tumour progression through action potential firing, increasing ATP demand and oxidative phosphorylation dependency, whereas non-neuroendoc...

Did you know cancer cells can be electrically active, just like neurons? This electrical activity plays a key role in tumor progression. Excited to share my first postdoc paper at @crick.ac.uk (and first paper from Leanne Li lab), published in @natureportfolio.nature.com!

Science at Risk: Protect NOAA Scientists & experts: Add your name to this open letter calling on Congress and the Trump administration to ensure that NOAA and its sub-agencies remain fully funded and staffed, and that the independ...

Scientists! An open letter from @ucsusa.bsky.social urging the Trump admin to leave NOAA intact 🧪

secure.ucsusa.org/a/2025-prote...

While there are still many ways that global warming will impact the biosphere, this is a little piece of good news that brightened up my feed.

Artificial sweetener triggers an insulin spike, which negatively impacts cardiovascular health #inmice 🐁 www.cell.com/cell-metabol...

Learn more @cp-cellmetabolism.bsky.social
#ShandongUniversity Yun Zhang, Yuguo Chen, Cheng Zhang
@ki.se Yihai Cao

Taking the Wheel: Jennifer Doudna, Emmanuelle Charpentier, and the CRISPR-Cas9 Revolution in Gene Editing. Over the course of the last two decades, humanity has taken its first quiet steps from being the blind victims of genetic-molecular chance towards becoming purposeful actors in our biological fates.  ...

Happy 61st to CRISP-Cas9 co-discoverer Jennifer Doudna! Her work on ribozymes led her to questions about bacteria's self defense systems against viral attack that laid the groundwork for the discovery of CRISPR's powerful gene editing ability.

tinyurl.com/z4krfuk5

#WomenInSTEM #BioSky #HistSci 🧪

The Glacier Mass Balance Intercomparison Exercise is out! Herculean effort bringing together >200 estimates of glacier loss outside the ice sheets. Bottom line is 273 gigatonnes per year of ice loss since the year 2000! 😲

Open-access article: doi.org/10.1038/s415...

🥼❄️ @natureportfolio.nature.com

Stand up for Science March 7, 2025
#ScienceSky #MedSky #SciSky
@altnps.bsky.social
@altcdc.bsky.social
@altnih4science.bsky.social

Clinical applications of human organoids - Nature Medicine Organoid research is moving beyond developmental and disease biology, driving insights into current and emerging health threats and enabling personalized and regenerative medicine applications.

A Review in Nature Medicine examines how organoid research is moving beyond developmental and disease biology, driving insights into current and emerging health threats and enabling personalized and regenerative medicine applications. 🔒

This is figure 1, which shows the global distribution of study locations of pesticide impact on non-target organisms.

A study in Nature Communications found that insecticides, fungicides and herbicides have negative effects on non-target plants, animals and microorganisms within terrestrial and aquatic systems. https://go.nature.com/4aY865i 🧪

This is figure 1, which shows the time required to detect a new pathogen with a global surveillance network at airports.

A study in Nature Medicine shows how global aircraft-based wastewater surveillance networks would perform in identifying sources of pandemic outbreaks and what the optimal location of monitoring sites would be. https://go.nature.com/3QkT549 #Medsky 🧪

Cross-priming in cancer immunology and immunotherapy - Nature Reviews Cancer

Melero&Co discuss the crucial role of conventional type 1 dendritic cells in cross-presenting antigens to prime CD8+ T cells to mount anti-tumour immunity and highlight how this can be exploited for #CancerImmunotherapy
@unav.edu
📖 ⬇️

TWiV 1187: The tau of herpesvirus

This week TWiV discusses the article: Anti-herpetic tau preserves neurons via the cGAS-STING-TBK1 pathway in Alzheimer's disease

Hosts: Vincent Racaniello, Kathy Spindler, Brianne Barker, Angela Mingarelli, Alan Dove

This is figure 1, which shows a summary of the systematic review dataset.

Genetic diversity has declined within two-thirds of more than 600 species over the past three decades, according to research published in Nature. The findings highlight the need for conservation efforts to prevent genetic diversity loss. https://go.nature.com/42EpVo5 🧪