So great to finally see this work out ✨ thanks to everyone involved over the years!

Thanks a lot, Ana :)

And just like these acylations acting in concert rather than independently, this work was a massive team effort 💪 Huge thanks to all the amazing collaborators, co-authors and friends!!! 🧵 3/3

We took a closer 👀 at H4K16 acylations: From in vitro assays to in vivo metabolic disease models! These acylations modulate inter- & intranucleosomal interactions and provide resilience to metabolic challenges. 🧵2/3

H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations Histone modifications play crucial roles in genome function. However, how chromatin integrates physiological and metabolic responses at the molecular …

Paper alert 🚨
Are you interested in the connection between epigenetics and metabolism? Then check out our new paper 🎁 👉 www.sciencedirect.com/science/arti... 🧵1/3

We took a closer 👀 at H4K16 acylations: From in vitro assays to in vivo metabolic disease models! These acylations modulate inter- & intranucleosomal interactions and provide resilience to metabolic challenges. 🧵2/3