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Posts by wozzi

True genius

2 hours ago 0 0 0 0
Aircraft equipped with 2 rotary jets at the end of 2 short wings.

Aircraft equipped with 2 rotary jets at the end of 2 short wings.

Doodle.

3 hours ago 56 12 0 0

SHIVERS - Meet me there -- wafting above the burnt ruins. Le Retour is waiting.

ESPRIT DE CORPS - And Station 41 and the glow of its desk lamps, the clicking of coffee mugs, clouds of cigarette smoke and the ringing telephone... your youth. There is still a way back.

2 days ago 64 7 0 0
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Working at nightt

3 days ago 32 7 0 1

Salute to an all-time tweet

3 days ago 7673 1766 146 27
Reddit post with a photo of the Tower of Babel built on the player's island in Tomodachi Life: Living the Dream. The post is titled "miis building on their own?!" and has a description "woke up to this huge tower!! i think they're trying to reach me... how do i punish them?"

Reddit post with a photo of the Tower of Babel built on the player's island in Tomodachi Life: Living the Dream. The post is titled "miis building on their own?!" and has a description "woke up to this huge tower!! i think they're trying to reach me... how do i punish them?"

3 days ago 3356 973 13 8

Hey artists, if you see this, post a dog

3 days ago 490 104 9 28
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3 days ago 1075 260 14 14
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Hey Folks!
I'm outta work for the time being and got bills to pay
I've got Comms open or if you're just feeling generous and wanna slide me a few bucks!
Check out my KOFI
ko-fi.com/toastietv

#Commission #Art

10 months ago 2299 502 13 18

why should he tbh

4 days ago 1 0 0 0
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5 days ago 3272 738 13 10
ABSTRACT
Viral pandemics continue to threaten global health and economic stability. Despite medical advances, the absence of broad-spectrum antivirals (BSAs) prevents rapid responses to emerging viral threats. This is largely due to the lack of universal drug targets across diverse viral families and high variability among viral proteins.
In this study, we evaluated 57 synthetic carbohydrate receptors (SCRs) for antiviral activity in cellulo using pseudotyped virus particles (PVPs) from six high-risk viruses across three families: Paramyxoviridae, Filoviridae, and Coronaviridae.
Four SCRs inhibited all tested PVPs, and their efficacy was confirmed against live viruses including SARS-CoV-2, MERS-COV, EBOV, MARV, NiV, and HeV.
Notably, SCR005 and SCR007, which exhibited minimal toxicity, significantly reduced SARS-CoV-2 infection in a severe animal model with a single dose.
Mechanistic studies suggested that SCRs bind viral envelope N-glycans, blocking viral attachment and/or fusion.
These results identify conserved viral N-glycans as promising BSA targets and establish SCRs as candidate prophylactic agents against enveloped viruses with pandemic potential.

ABSTRACT Viral pandemics continue to threaten global health and economic stability. Despite medical advances, the absence of broad-spectrum antivirals (BSAs) prevents rapid responses to emerging viral threats. This is largely due to the lack of universal drug targets across diverse viral families and high variability among viral proteins. In this study, we evaluated 57 synthetic carbohydrate receptors (SCRs) for antiviral activity in cellulo using pseudotyped virus particles (PVPs) from six high-risk viruses across three families: Paramyxoviridae, Filoviridae, and Coronaviridae. Four SCRs inhibited all tested PVPs, and their efficacy was confirmed against live viruses including SARS-CoV-2, MERS-COV, EBOV, MARV, NiV, and HeV. Notably, SCR005 and SCR007, which exhibited minimal toxicity, significantly reduced SARS-CoV-2 infection in a severe animal model with a single dose. Mechanistic studies suggested that SCRs bind viral envelope N-glycans, blocking viral attachment and/or fusion. These results identify conserved viral N-glycans as promising BSA targets and establish SCRs as candidate prophylactic agents against enveloped viruses with pandemic potential.

Their efficacy was confirmed against LIVE viruses including Ebola, Marburg, Nipah, Hendra, SARS-CoV, SARS-CoV-2 (COVID-19), AND Middle East Respiratory Syndrome (MERS).

The study has been published in Science Advances. YES, it is PEER-REVIEWED.
• www.science.org/doi/10.1126/...

🧪🧵⬇️

5 days ago 395 102 6 8

Europe won't be safe until all US and Israeli tech firms are kicked out, and replaced entirely with domestic alternatives, permanently.

5 days ago 45 14 1 1
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help a mutt make rent- get yourself a wunk 2day. DM me!

#furry #furryart

1 month ago 21 11 0 1

Tired: Boys will be boys
Wired: Boys will be dead if they try this shit with my kid

1 week ago 181 28 7 1
Preview
Donate to Support for Heather, Nolan & Alex, organized by Jen Bickel-Hayes Support for Heather, Nolan & Alex We are heartbroken to share the unexpected pa… Jen Bickel-Hayes needs your support for Support for Heather, Nolan & Alex

One of my very dear friends has passed away suddenly. If you ever played #Halo2 or #Halo3 you've seen his work in action & I would like to ask you to donate to his family if you can or share please!
Nate was a fantastic animator, professor, & mentor who is sorely missed already.
gofund.me/53467d769

2 weeks ago 1 2 1 1
Traditional painting of a colorful abstract coyote with vibrant shades of pink, orange, and blue against a yellow background. A bright pink sun shape frames its head.

Traditional painting of a colorful abstract coyote with vibrant shades of pink, orange, and blue against a yellow background. A bright pink sun shape frames its head.

✦ colorful coyote ✦

1 week ago 861 281 6 0
retro video game :

YOU SEE YOURSELF IN THE mIRROR. YOU AGRIN REALIZE WITH HORROR THAT YOU CAN'T REMEMBER WHO YOU ARE!!

retro video game : YOU SEE YOURSELF IN THE mIRROR. YOU AGRIN REALIZE WITH HORROR THAT YOU CAN'T REMEMBER WHO YOU ARE!!

logging on

3 months ago 15 2 0 0
The “Calvin’s dad explains two types” meme, inspired by a Calvin and Hobbes cartoon.

Clockwise from top left:
1) Calvin’s dad walks into frame to find Calvin trying to operate a record player. The dad says: “There are only two industries left in America: gambling, and fraud.”

2) The dad shows where the record goes, and how to turn on the player, while Calvin watches. Dad says “Derivatives? Gambling. AI? Fraud. Video games? Gambling. Social media? Fraud.” Calvin says “yeah”.

3) With one hand open palm up, Calvin’s dad cheerfully explains to Calvin out of frame below him, “The stock market looks like gambling, but it’s actually fraud.”

4) In bed in a dark room, Calvin clutches at his pillow, eyes wide in existential terror. There is no text in the panel.

The “Calvin’s dad explains two types” meme, inspired by a Calvin and Hobbes cartoon. Clockwise from top left: 1) Calvin’s dad walks into frame to find Calvin trying to operate a record player. The dad says: “There are only two industries left in America: gambling, and fraud.” 2) The dad shows where the record goes, and how to turn on the player, while Calvin watches. Dad says “Derivatives? Gambling. AI? Fraud. Video games? Gambling. Social media? Fraud.” Calvin says “yeah”. 3) With one hand open palm up, Calvin’s dad cheerfully explains to Calvin out of frame below him, “The stock market looks like gambling, but it’s actually fraud.” 4) In bed in a dark room, Calvin clutches at his pillow, eyes wide in existential terror. There is no text in the panel.

1 week ago 13308 4665 60 87
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this being the thing that crosses the line for many rightwingers is so illustrative of how they don’t really care about anything real that actually matters. their problems are all entirely fictional

1 week ago 10984 1583 280 87
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Augmenter le nombre de trains, réparer les voies ferrées… Comment financer ? Une loi-cadre est sur la table
🔗https://l.sudouest.fr/nN0f

1 week ago 3 1 0 0
A453 Nottingham
A50 Stoke, Derby

A453 Nottingham A50 Stoke, Derby

derby, uk

1 week ago 2804 646 7 4
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おはようございます!(:D)┓
【外濠-中央線】E353系[あずさ]東京-松本~送り込み回送:桜
【西大井駅-横須賀線】E259系[成田エクスプレス]成田空港-大船
【松住町架道橋/昌平橋-総武線】E257系[特急新宿さざなみ]館山-新宿
【荒川中川橋梁-総武線】←キヤE193系気動車East i-D:秋田県からようこそ!
#鉄道 #railway #さくら #桜

1 week ago 223 12 25 0
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↑上の元ポストからの続き
 朝投稿にたくさんのコメントありがとうございます!名前(ユーザーネーム)ごと全て読んでいます!いいね、リポスト、閲覧のみもとってもありがとうございます!
🚃【西大井駅-横須賀線】E235系 横須賀総武快速線 久里浜行
🚃【西大井駅-横須賀線】E235系 横須賀総武快速線 横須賀行 列車後方-LEDは4月のさくら
《ワクぎりぎりまで撮るので、写真はタップ推奨です。ハイライトタブに朝投稿を並べてあります。》
 それでは今日も一日、大吉☆強運☆安全で( ゚∀゚)o

1 week ago 81 6 0 0
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1 week ago 2064 579 16 10

True geniud

1 week ago 0 0 0 0
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Sergiu Ciochină (Moldavian/French, born 2001)
"Bergen, Norway", 2025.
Oil on Board, 35 × 50 cm.
Private Collection.

#art #painting #artist #BlueSkyArt

1 week ago 77 10 1 0
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Concept sheet of early character development sketches for Amanda Ripley from Creative Assembly's ALIEN: Isolation (2011)

Concept sheet of early character development sketches for Amanda Ripley from Creative Assembly's ALIEN: Isolation (2011)

Early character development sketches for Amanda Ripley from Creative Assembly's ALIEN: Isolation (2011)

1 week ago 913 172 7 3
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Was overdue to design a skulldog they're so cool

1 week ago 1928 410 24 2

Gratz to Hungary for kicking orban to the curb btw🙂‍↕️🎉

1 week ago 11 2 0 0