Life Science Research Professional 1 (Multiple Positions) in School of Medicine, Stanford, California, United States Stanford University is seeking a Life Science Research Professional 1 to study the mechanisms of aging and rejuvenation, with a focus on diverse...

Bittersweet day in the Wyss-Coray Lab!
Proud to see Jinglin & Eduardo head off to their PhDs.

Want to be next? Come work with us #Stanford! Come for the science, stay for the mentorship.

Apply: careersearch.stanford.edu/jobs/life-sc...

We are training the #NextBioLeader!

Join us in congratulating the CCAD Cohort of 2026! We look forward to their innovative contributions to the field of Alzheimer’s disease and the CCAD community.

#CCAD2026 #AlzheimersDisease #NewVisionResearch

Spatial and molecular insights into microglial roles in cerebellar aging www.biorxiv.org/content/10.1101/2025.03....

Spatial and molecular insights into microglial roles in cerebellar aging www.biorxiv.org/content/10.1101/2025.03....

Simultaneous analysis of single-cell gene expression and morphology provides new insight into how microglia change with age www.biorxiv.org/content/10.1101/2025.02....

Simultaneous analysis of single-cell gene expression and morphology provides new insight into how microglia change with age www.biorxiv.org/content/10.1101/2025.02....

Color-neutral and reversible tissue transparency enables longitudinal deep-tissue imaging in live mice Light scattering in biological tissue presents a significant challenge for deep in vivo imaging. Our previous work demonstrated the ability to achieve optical transparency in live mice using intensely...

Excited to share this collaborative work led by Guosong Hong’s group @stanfordneuro.bsky.social. A new method to render animals optically transparent for deep tissue imaging across the visible spectrum 🌈

www.biorxiv.org/content/10.1...

‘Slime’ keeps the brain safe ― and could guard against ageing Slippery proteins in the brain’s blood vessels form a protective barrier that breaks break down with age, studies in mice show.

Slippery proteins in the brain’s blood vessels (vascular glycocalyx) form a protective barrier that breaks break down with age @carolynbertozzi.bskyverified.social #wysscoray @sophiamshi.bsky.social @nature.com
www.nature.com/articles/d41...
www.nature.com/articles/s41...

Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease - Nature Disruption of mucin-domain glycoprotein expression and function in the endothelial glycocalyx are associated with ageing and Alzheimer’s disease, leading to dysregulated blood–brain barrier function.

Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease

www.nature.com/articles/s41...

A high-throughput assay platform to discover small molecule activators of the phospholipase PLC-γ2 to treat Alzheimer’s disease A naturally occurring missense variant of the phospholipase C isozyme, PLC-γ2, harboring a single substitution (P522R) protects against several neurodegenerative diseases, including Alzheimer’s diseas...

Excited to be part of the work-"A high-throughput assay platform to discover small molecule activators of the phospholipase PLCG2 to treat Alzheimer’s disease"- now out in JBC !
Huge thanks to Qisheng and the team for this amazing collaborators! www.jbc.org/article/S002...

Microglia stuffed with fat struggle. Knocking out a lipid-droplet regulator in them boosted their appetite for Aβ and tempered plaque load.

www.alzforum.org/news/researc...

Interested in brain aging? We are super excited to share our new review!!

"Brain aging and rejuvenation at single-cell resolution" 🧪🧠

Massive CONGRATS to Eric Sun, Rahul Nagvekar, and Angie Pogson, three phenomenal graduate students in the lab!!

authors.elsevier.com/sd/article/S...

Thank you so much!

Dear Anne, If possible, I would like to be added and learn more from scientists in the field of aging! Thank you!

Hi Oliver, if possible I would like to be added! I am a postdoc working on hematopoietic stem cells in brain aging and Alzheimer's disease! Thank you!

Updated Aging Starter Packs to find people and labs who work on aging!!

Aging Starter Pack 1 (already reached the maximum number!): go.bsky.app/5UXXaDA

Aging Starter Pack 2 (can still add!): go.bsky.app/RfFYndJ

Let me know if you'd like to be added! 😀

Welcome! You are invited to join a webinar: Immunity and Neurodegeneration PIA: APOE and Lipid Droplets. After registering, you will receive a confirmation email about joining the webinar. Experts reveal how APOE influences astrocyte lipid droplets and how microglial lipid droplet accumulation is linked to brain tauopathies. Discover cutting-edge research on the role of lipid metabolism...

💘 Celebrate Valentine’s Day with cutting-edge science on APOE and lipid droplets!
Join the ImmunityPIA webinar on 2/14/2025!

🎤 Speakers:
@cohenlaboratory.bsky.social
Dr. Xu Chen

🌟 Panelists:
Dr. Kimberley Bruce
Dr. Lance Johnson
👉 Register now:
alz-org.zoom.us/webinar/regi...

Don’t miss it!

CD33 isoforms in microglia and Alzheimer's disease: Friend and foe Alzheimer's disease (AD) is the most common form of neurodegenerative disease and is considered the main cause of dementia worldwide. Genome-wide asso…

It is also a good candidate for Alzheimer’s disease: www.sciencedirect.com/science/arti...!