Signed this petition to support the NIH and oppose the proposed cap on indirect costs. This policy will have devastating effects on biomedical research, patient care, and the economy, as outlined in the @cellpress.bsky.social essay below.
chng.it/YSStHP9h25
www.cell.com/cell/fulltex...
Biomedical researchers, @aimbe-official.bsky.social is seeking anecdotes about how recent policies have disrupted your grants/research: aimbe.wufoo.com/forms/qs9tsi...
Your messages are critical for us to advocate to our Members of Congress to take action against these federal disruptions 👇
AIMBE is looking for biomedical researchers to share how recent policies have disrupted their grants/work: aimbe.wufoo.com/forms/qs9tsi...
Your personal anecdotes are essential in helping us convey to Members of Congress the devastating impact of these changes.
Your response can remain anonymous.
Want to reach out to your representatives about the recent indirect cost cap at the @NIH? Take 30 seconds and fill out @aimbe's pre-drafted letter here: https://buff.ly/42SQ8iP
@orssociety.bsky.social @bmes-cmbe.bsky.social @acs.org #ORSSMC
Thank you! :)
Thank you for organizing! Could you please add me?
Thank you!
Thank you for organizing, Hannah! Could you please add me?
Could you please add me? Thank you for organizing!
Had such an amazing time at #TERMIS2024! Thank you so much to co-chairs @nasimannabi & @cosgriffhernan for organizing such an extraordinary event! And, thank you to our fellow SYIS council members for all their efforts in leading our young investigator activities!
Excited to share this review article Jin and I worked on this past year with @JHElisseeff! We reviewed how the immune system and aging impact the response to biomaterials for musculoskeletal tissue regeneration.
@jintheanswer
onlinelibrary.wiley.com/doi/full/10.1002/adma.20...
Grateful for the opportunity to present my postdoc and PhD research at #TERMIS2023 on Thursday! Feel free to attend if you are interested in how aging impacts the biomaterial response, or in 3D bone imaging. Thank you @JHElisseeff and @GraysonLab for your amazing mentorship!
These contractors have been in Fell's Point for months and have been very unpleasant to deal with. They've been very unprofessional while working on our property and have made a mess out of our roads and sidewalks throughout the neighborhood. @Zeke_Cohen @MayorBMScott
I said yes to my partner and best friend of 8.5 years this weekend! Excited to start this next chapter of our lives together!
If you're at @SFBiomaterials #SFB2022, I'll be presenting our @GraysonLab research using #tissueclearing & #lightsheet imaging to study the interactions between transplanted stem cells, blood vessels, and nerves during bone healing. Feel free to stop by tomorrow (4/28) at 1 pm!
Defended my PhD thesis today! It still feels a bit surreal, but I am very happy to be #PhDone!
Starting 2022 with a dusting of AZ snow. I wish everyone a happy and healthy New Year! 🎉🎉
Is it just me, or does eating lunch at work feel as awkward as it did a year ago? 😂
Gave this a try on my thesis. Maybe I can use it for Halloween decorations next year. 😂
"Quantitative 3D imaging of the cranial microvascular environment at single-cell resolution"
https://app.wombo.art/
Thanks to my boyfriend Kyle for a wonderful birthday dinner at Water for Chocolate! I'm trying to take advantage of those peak Moderna booster antibodies while they last 😂 I definitely recommend WFC for those living in Baltimore if you haven't been yet!
Experiencing a roach infestation in my kitchen 😬 Anybody have recommendations for exterminators in the Baltimore area?
Lastly, our datasets are publicly available for anyone interested in seeing our images in 3D! (16/16)
www.ebi.ac.uk/biostudies/BioImages/stu...
And, of course, I want to thank my advisor, Prof. Warren Grayson (@GraysonLab), for supporting me through all this work. His guidance and encouragement have been essential for me to navigate this challenging (but very rewarding) project! (15/16)
Special thanks to @srsnyder_biomed for creating this wonderful illustration to summarize our findings! (13/16)
Our quantitative imaging platform can also be readily adapted to study other cell types and molecules in cranial bone. (I promise that it is easy to learn and repeatable!) (12/16)
Taken together, our findings provide a foundational framework for how cranial blood vessels interact with skeletal progenitors and will enable more targeted approaches to engineering vascularized craniofacial bone. (11/16)
Using a cranial defect injury model, we found that CD31(hi)Emcn(hi) vessels—along with Gli1+ progenitors—infiltrate the entire defect area during the early stages of healing. This result implicates a potential role for these vessels in driving cranial bone healing. (9/16)
However, conditionally knocking out PDGF-BB in TRAP+ osteo/pre-osteoclasts disrupted this relationship, which suggests that these bone-resorbing cells may be critical in maintaining the native cranial microvascular environment. (8/16)
We discovered that CD31(hi)Emcn(hi) vessels were spatially correlated with Osterix+ and Gli1+ progenitors during growth and healing. This relationship was most prominent at the transcortical canals (white arrowheads), where periosteal vessels connect to marrow sinusoids. (7/16)
Using this platform, we generated 3D maps of the vasculature and skeletal progenitor cells in the calvarium during postnatal growth, remodeling, and healing. We labeled blood vessels with CD31 and Endomucin, osteoprogenitors with Osterix, and skeletal stem cells with Gli1. (6/16)