Congratulations to all co-authors on these achievements and for their fantastic team work.

Epigenetic regulation by HDAC11-driven STAT3 activation promotes pro-inflammatory cytokine production and endothelial dysfunction upon bacterial infection in diabetes - PubMed Epigenetic regulation by HDAC11-driven STAT3 activation promotes pro-inflammatory cytokine production and endothelial dysfunction upon bacterial infection in diabetes

second paper focuses on HDAC11 in diabetes-induced inflammation. Diabetes is associated with inflammation, endothelial cell dysfunction, and increased susceptibility to infections. HDAC11 plays a key role in this inflammatory pathway.
pubmed.ncbi.nlm.nih.gov/41668160/

SIRT1 mediates brain metabolic and developmental consequences of methionine synthase deficiency in inborn errors of cobalamin metabolism - PubMed Inborn errors of vitamin B12 metabolism (IECM) resulting from impaired methionine synthase (MTR) activity cause severe cognitive and neurological deficits that remain unresponsive to conventional B12 supplementation. Using a brain-specific Mtr knockout mouse model, we identify the NAD⁺-de …

first study describes SIRT1 in vitamin B12-associated inborn errors of metabolism. Impaired Methionine Synthase in brain leads to dysregulated WNT signalling and neurological defects. SIRT1 plays a central role and restoring SIRT1 can largely rescue the phenotype.
pubmed.ncbi.nlm.nih.gov/41747718/

Happy to contribute to two new collaborative papers, both involving epigenetic dysregulation in disease mediated by HDACs: 👇

If you are a student from China, and interested in doing a PhD in my group in stem cell and cancer epigenetics, this would be a great opportunity (a dedicated scholarship).

Deadline for initial application is January 27th.

www.qub.ac.uk/Study/intern...

Deadline Jan 5th.

We have an exciting postdoc position supported by MRC funding to study the interplay between epigenetics and cellular metabolism in human ESCs.

Application deadline January 5th of January 2025.

hrwebapp.qub.ac.uk/tlive_webrec...

www.atlasilab.com

We have an exciting postdoc position supported by MRC funding to study the interplay between epigenetics and cellular metabolism in human ESCs.

Application deadline January 5th of January 2025.

hrwebapp.qub.ac.uk/tlive_webrec...

www.atlasilab.com

🚨 Multiple #PhD opportunities for lab or computational applicants. Do you want to understand the molecular basis of #epigenetic dysfunction in human disease?
Come work with our group at the fantastic, collaborative @uoe-igc.bsky.social in a beautiful, liveable city.
🧵 1/4
Please repost 🙏

So happy to visit Sheffield again to share our research and discuss science with brilliant minds.

Also finally visited the site of Krebs’s original lab 🙂

Join us for an extraordinary evening with Nobel Laureate Svante Pääbo!

Prof Pääbo will present a FREE public talk titled “Of Neanderthals and Denisovans, and how they live on in many of us” at the @crick.ac.uk.

Register here: genetics.org.uk/events/of-ne...

Targeting USP7-PRC1 axis as a novel therapeutic approach in drug resistant Diffuse Large B-Cell Lymphoma at Queen’s University Belfast on FindAPhD.com PhD Project - Targeting USP7-PRC1 axis as a novel therapeutic approach in drug resistant Diffuse Large B-Cell Lymphoma at Queen’s University Belfast, listed on FindAPhD.com

We have an exciting, fully funded PhD studentship (UK and ROI) to investigate mechanisms of epigenetic regulation in drug resistant B-cell lymphoma.

We are looking for a highly motivated, driven candidate to join our team.

eur02.safelinks.protection.outlook.com?url=https%3A...

Targeting USP7-PRC1 axis as a novel therapeutic approach in drug resistant Diffuse Large B-Cell Lymphoma at Queen’s University Belfast on FindAPhD.com PhD Project - Targeting USP7-PRC1 axis as a novel therapeutic approach in drug resistant Diffuse Large B-Cell Lymphoma at Queen’s University Belfast, listed on FindAPhD.com

We have an exciting, fully funded PhD studentship (UK and ROI) to investigate mechanisms of epigenetic regulation in drug resistant B-cell lymphoma.

We are looking for a highly motivated, driven candidate to join our team.

eur02.safelinks.protection.outlook.com?url=https%3A...

Starting the UK stem cell network conference, with a welcome address by one of my scientific heroes. #UKSCN25

AstraZeneca pauses £200m investment in Cambridge research site Decision means none of drugmaker’s much-trumpeted £650m UK investment package is currently proceeding

www.theguardian.com/business/202...

Very much looking forward to this excellent conference next week in Manchester; very important for the UK’s stem cell research community

Thank you

Please share: we’re recruiting a postdoctoral fellow – applications open until September 15!

To lead genomics data analysis of an exciting translational project in sAML cancer, supportive environment, and access to unique in-house technologies.

my.corehr.com/pls/uoxrecru...

Very grateful to receive a new BBSRC grant and many thanks to #BBSRC panel, and reviewers for this generous support. This funding will enable us to address important unresolved questions in chromatin regulation downstream of WNT/GSK3 signalling in stem cells. @wntuk.bsky.social

Genetic Society Autumn meeting
@gensocuk.bsky.social

Ancient genomes: perspectives on human biology and medicine | Genetics Society It is our great pleasure to invite you to participate in the Autumn Meeting of the Genetics Society. This meeting will provide a unique forum to network and socialise with a wide cross-section of the ...

We’ve got some good news! The deadline to submit abstracts for our “Ancient #Genomes: Perspectives on Human Biology and Medicine” meeting has been extended to 31 July 2025. So if you were thinking about submitting, there’s still plenty of time!

genetics.org.uk/events/ancie...

Ancient genomes: perspectives on human biology and medicine | Genetics Society It is our great pleasure to invite you to participate in the Autumn Meeting of the Genetics Society. This meeting will provide a unique forum to network and socialise with a wide cross-section of the ...

Last day to submit your abstracts to our Ancient Genomes meeting @royalsociety.org. Invited speakers include Lluis Quintana-Murci, Iain Mathieson, Priya Moorjani and Svante Pääbo!

genetics.org.uk/events/ancie...

Had a fantastic time at the INSERM grant review panel in Paris. It was truly inspiring to see so many talented young scientists; but only then you realize how challenging it is to choose the best among them.
A great learning experience, without a doubt.

Genetics Society Anniversary Day 2025 | Genetics Society We are pleased to announce the Genetics Society Anniversary Day, which will be held on 25th June 2025. This event will celebrate several of our prize winners and the summer students we have supported....

Join us on our anniversary day!

This event will celebrate our prize winners and the summer students we have supported. It will also host a presentation by Prof Richard Durbin to recognise the anniversary of Sanger sequencing and the first draft of the human genome.

genetics.org.uk/events/genet...

Very much looking forward to my visit to the QMUL Centre for Epigenetics and the opportunity to discuss science with experts in the field.

Fully Funded PhD Studentship in Human Genetics, Genomics and Disease: Dissecting DNMT3B functions in Immunodeficiency-centromeric instability facial anomalies syndrome at University of Edinburgh on Fi... PhD Project - Fully Funded PhD Studentship in Human Genetics, Genomics and Disease: Dissecting DNMT3B functions in Immunodeficiency-centromeric instability facial anomalies syndrome at University of E...

Want to work with us on DNA methylation and rare genetic disease? Fully funded PhD project with deadline 16th May:
www.findaphd.com/phds/project...
Excited to collaborate with @hannahlong.bsky.social and Daria Bunina (@uoe-igc.bsky.social/@mdc-berlin.bsky.social).
Please share 🙏
#epigenetics

Congratulations to @janayf.bsky.social for winning the 2025 Bruce Cattanach Prize from @gensocuk.bsky.social and for delivering an amazing talk.

Thank you for your valuable contribution Peter, it was a fun meeting.

Deadline is Monday 28th.

Big congratulations to Prof. Kathy Niakan on receiving the 2025 Mary Lyon Medal from the Genetics Society UK in recognition of her outstanding research in genetics and developmental biology
@niakanlab.bsky.social
@gensocuk.bsky.social