Thrilled to present our comparative study on the evolution of zygotic genome activation (ZGA)!! 🥚🧬

Amazing PhD work of @campobes.bsky.social together with @fedemantica.bsky.social and many collaborators! @melisupf.bsky.social @crg.eu. Thread below 1/15

www.biorxiv.org/content/10.6...

Associate Senior Lecturer/Assistant Professor in Molecular Microbiology The Department of Biology conducts research and teaching in many subject areas such as ecology, evolutionary biology, organismal biology and molecular biology. A total of approximately 300 people curr

Associate Senior Lecturer/Assistant Professor position in Molecular Microbiology available at Lund University, Sweden:
lu.varbi.com/en/what:job/...

@csic.es @csicandalextrem.bsky.social @pablodeolavide.upo.es @embo.org @erc.europa.eu @ageinves.bsky.social

A week left to apply to our fully funded PhD studentship (thanks to the Generation Trust!) - entry point updated to either June or October (so no worries if you are currently finishing your MPhil!). Don't hesitate to contact me with any questions about the opportunity or the project itself.

If you’re at #dros26 and you like transposons don’t miss Peiwei’s talk! 🔥🪰 We’re really excited about his findings!

🚨 Job Alert - Please share! 🙏

Interested in 3D gene regulation in development & evolution? 🤓🧬

💥 Our lab at @cabd-upo-csic.bsky.social is expanding!

We’re recruiting:
✅ PhD students
✅ Postdocs
💻🧪 Experimental or computational backgrounds welcome

👇 Details below

Team ILLUMINE, featuring our Hannon Group, will receive up to $25m over five years to take on the challenge of the dark proteome as part of Cancer Grand Challenges.

Full story: www.cruk.cam.ac.uk/news/hannon-...

Primate-specific gene regulatory networks responsive to inflammation and DNA damage This project will investigate gene regulatory networks controlled by primate-specific transposable elements responsive to inflammation and DNA damage and probe how they are disrupted in cancer.

We have a fully-funded PhD studentship opportunity in my group to study primate-specific gene regulatory networks related to inflammation and DNA damage, in collaboration with @frostlab.bsky.social - please apply or send to promising candidates (UK Home fees eligible only), deadline is March 18th.

Molecular #evolution of animal #aging:
A field perspective explores the impact of evolution on aging and offers a multi-angle view on longevity variation across model organisms and environments
link.springer.com/article/10.1...

Protocol for efficient CRISPRi-mediated silencing of retrotransposons in human pluripotent stem cells Here, we present a workflow for transcriptional silencing of transposable elements (TEs) in human induced pluripotent stem cells (hiPSCs). We describe steps for designing guide RNAs (gRNAs) to target ...

Are you interested in achieving efficient silencing of transposable elements using CRISPRi? 🧬 🧫
Go ahead and have a look at this STAR protocols where Adami et al. share all the tips & tricks they use in the Jakobsson lab.

@anitaada.bsky.social @raquelgarza.bsky.social @jakobssonlab.bsky.social

TE x ZFP = Evolution!
Writing this with Olga @orpsf.bsky.social & Didier @trono-lab.bsky.social was a major highlight of my 🇨🇭sabbatical. Such a treat! 🍫Hope you enjoy it as much as we enjoy piecing it together.

Concurrent L1 retrotransposition events promote reciprocal translocations in human tumorigenesis LINE-1 (L1) retrotransposition generates somatic genomic variation in human cancer, but short-read sequencing has limited our understanding of its structural consequences and dynamics. Using long-read...

Today in
@science.org:
We are pleased to present our last work entitled:
"Concurrent L1 retrotransposition events promote reciprocal translocations in human tumorigenesis"
by Zumalave et al.
www.science.org/doi/10.1126/...

If you want to explore ncRNA dynamics during mammalian development, love microscopy, and are not afaraid of transposons biology, apply‼️
We are looking for a postdoc to join our team at @imbavienna.bsky.social
More details 👇🏻

The role of KRAB zinc-finger proteins in expanding the domestication potential of transposable elements - Nature Genetics This Perspective explores the co-evolution of transposable elements and KRAB zinc-finger proteins in relation to their integration into human gene regulatory networks, highlighting their potential eff...

Find our latest Perspective article in Nature Genetics on "The role of KRAB zinc-finger proteins in expanding the domestication potential of transposable elements" at www.nature.com/articles/s41..., with implications for the future of research on the cause of human disease.

Finally found the time to make a BlueSky account, last year was very busy moving to London for my new position at King's College London, looking forward to rejoin the amazing transposable element community!