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Posts by Sam Mugford

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I think about this study a lot.

The world's a gymnasium... if you notice it.

1 day ago 18 3 5 0

The Witcheta lineman is still on the liiiiinnn-n-n-n-n-ak-ak-ak-ak *bass drops*

2 days ago 1 0 0 0

Very disappointing to hear @markmiodownik.bsky.social on Toxic on Radio4 tonight. Lots of scaremonging about possible risks, lots of correlation without mechanistic mechanism, very little evidence of real harm but lots of advice for people to change their lifestyle.

2 days ago 0 0 0 1

go home biology, you’re drunk.
reverse transcriptase is now taking sequence instructions from a protein

4 days ago 53 16 0 1
Two Bald Eagles with the Moon behind them

Two Bald Eagles with the Moon behind them

Good night, Bluesky!

What's better than a Bald Eagle in the Moon?🦅🌕

How 'bout 2 of 'em?🦅🌕🦅
📸Josh Palmer

1 week ago 5091 503 114 43

Its strangely apropriate to name this after somone famous for having her data stolen and not being given credit

4 days ago 21 9 0 0
A large green aphid fills the whole screen. Magenta splotches of the symbiont Buchnera are in the posterior end of the aphid

A large green aphid fills the whole screen. Magenta splotches of the symbiont Buchnera are in the posterior end of the aphid

I've been working to visualize the biogeography of the aphid's intracellular symbiont within whole insects. The pink bacteria live in the host's specialized bacteriocytes and embryos. Really excited about where this work is going! #FluorescenceFriday

1 week ago 44 8 2 0
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TSL Alumnus wins Biochemical Society Award Mauricio Contreras has been recognised as an exceptional Early Career Researcher by the Biochemical Society. Currently based at the University of Tübingen, Germany, Mauricio previously spent several…

We are happy to celebrate @mpcontreras.bsky.social winning the @biochemsoc.bsky.social 2027 Early Career Research Award!

Mauricio joined TSL as a predoc with @kamounlab.bsky.social, where he did PhD and postdoc before starting his group at @zmbp-tuebingen.bsky.social

Congrats Mau!

1 week ago 29 11 2 2
A European common cuttlefish (Sepia officinalis) wearing a pair of red and blue 3D glasses. They look cool as fuck. Their arms are reaching out and they have a sandy striped pattern

A European common cuttlefish (Sepia officinalis) wearing a pair of red and blue 3D glasses. They look cool as fuck. Their arms are reaching out and they have a sandy striped pattern

A European common cuttlefish (Sepia officinalis) wearing a pair of red and blue 3D glasses swimming just above the ground. They look very cool. They have a yellow sandy beige colour.

A European common cuttlefish (Sepia officinalis) wearing a pair of red and blue 3D glasses swimming just above the ground. They look very cool. They have a yellow sandy beige colour.

A European common cuttlefish (Sepia officinalis) wearing a pair of red and blue 3D glasses  sitting on the ground. Their two centre arms are raised and reaching back while the other limbs rest on the ground. They have a grey colour with brown spots. They look extremely cool.

A European common cuttlefish (Sepia officinalis) wearing a pair of red and blue 3D glasses sitting on the ground. Their two centre arms are raised and reaching back while the other limbs rest on the ground. They have a grey colour with brown spots. They look extremely cool.

A European common cuttlefish (Sepia officinalis) wearing a pair of red and blue 3D glasses  reaching for a projection of a shrimp. They look pretty cool. They have a sandy brown colour.

A European common cuttlefish (Sepia officinalis) wearing a pair of red and blue 3D glasses reaching for a projection of a shrimp. They look pretty cool. They have a sandy brown colour.

In 2019, scientists velcro'd 3D glasses to European common cuttlefish (Sepia officinalis)

They didn't do this just to make them look cool as fuck, but in order to study their vision. Using a 3D theatre made for the cuttlefish, they were able to test if cuttlefish have stereo vision (they do!)

1 week ago 442 177 4 14

Hungary has chosen Europe.

Europe has always chosen Hungary.

A country reclaims its European path.

The Union grows stronger.

1 week ago 23326 4458 463 267
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The Good News: From 1900 to 2023, almost half (46%) of countries that had gone from democracies to autocracies had REVERSED their democratic breakdown, with most of them ending or reversing the trend of autocratization within 5 years of its onset. (Nord & Lindberg, 2025).

1 week ago 67 19 1 1

Great to see this paper in its final published form!

www.pnas.org/doi/10.1073/...

2 weeks ago 25 14 3 0
The title page of the 1998 Technical Advance paper in the Plant Journal showing the title “Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana”, authors Steven J. Clough, Andrew F. Bent and publication date December 1998 (Volume 16, Issue 6, Pages 735-743)

The title page of the 1998 Technical Advance paper in the Plant Journal showing the title “Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana”, authors Steven J. Clough, Andrew F. Bent and publication date December 1998 (Volume 16, Issue 6, Pages 735-743)

#PlantScienceClassics #13: Floral Dip. ~25 years ago, in 1998, Steven Clough & Andrew Bent published their ingeniously simple Arabidopsis transformation protocol in #ThePlantJournal: Dipping a plant upside down into Agrobacterium solution - et voilà!
doi.org/10.1046/j.13...

1 year ago 17 10 1 2
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Preprint alert 🚨 (1/10) 🧵

𝘈𝘶𝘵𝘰𝘱𝘩𝘢𝘨𝘺 𝘪𝘴 𝘢 𝘱𝘢𝘳𝘢𝘥𝘰𝘹 𝘪𝘯 𝘱𝘭𝘢𝘯𝘵 𝘪𝘮𝘮𝘶𝘯𝘪𝘵𝘺:
It can promote resistance, susceptibility, or restrict cell death 🤯

So what is its actual role?

We show it acts as a spatial organizer of immunity across cell types 🌱🦠 #proteostasis

www.biorxiv.org/content/10.6...

1 week ago 106 55 7 2
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The FY 2027 NASA budget request hides its science cuts by omitting mission names instead of explicitly zeroing them out.

We did the work and found 54 missions cancelled in this proposal.

This is another extinction-level event for NASA science.

Full list: planetary.org/save-nasa-science

1 week ago 290 214 9 30

This is such a tragedy and a huge shock. Philippa had so much more to show the world.

1 week ago 1 0 0 0

"I shouldn't have to pay for YOUR kids"..."I shouldn't have to pay for YOUR elders" but here we are...in a society

2 weeks ago 499 77 8 3

The biggest story in the world right now is that the president of the United States is a demented old man who takes pleasure in torturing and killing people and is committing crimes with impunity. And yet most legacy media outlets are too cowardly to tell it like it is.

2 weeks ago 57263 16994 1496 846
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NASA just dropped this image of Artemis II astronaut Christina Koch looking back at us. The first woman to ever see our planet in its entirety. I’m not crying you’re crying 🥹🔭🧪 📸: NASA

2 weeks ago 36284 7609 340 339

There's no such thing as the Prisoner's Dilemma if you're not a grass.

2 weeks ago 13 1 1 0

- i dont want a goat

2 weeks ago 1 0 0 0
Spectacular high-resolution image of our home planet viewed through the Orion Crew Module window by the Artemis II astronauts as they continue their journey to the Moon on Flight Day 2, 3 April 2026 (pic: NASA)

Spectacular high-resolution image of our home planet viewed through the Orion Crew Module window by the Artemis II astronauts as they continue their journey to the Moon on Flight Day 2, 3 April 2026 (pic: NASA)

A full disc image of Earth, as seen from the Orion Crew Module. The planet is a pale blue, swirling with white clouds and glowing slightly lighter blue in place from reflected light. At lower left, a large brown landmass is Africa, with Spain and Portugal with twinkling lights where the planet curves. At top right, auroras glow in a thin green glow, just barely separated from the planet's surface. Earth is set against the black of space (pic: NASA/R.Wiseman)

A full disc image of Earth, as seen from the Orion Crew Module. The planet is a pale blue, swirling with white clouds and glowing slightly lighter blue in place from reflected light. At lower left, a large brown landmass is Africa, with Spain and Portugal with twinkling lights where the planet curves. At top right, auroras glow in a thin green glow, just barely separated from the planet's surface. Earth is set against the black of space (pic: NASA/R.Wiseman)

😮 Awesome views from Day 2 of #Artemis II this morning.

@exploration.esa.int @esaearth.esa.int

2 weeks ago 2897 1061 23 172

Remember all those years when they insisted on having a climate sceptic on ‘for balance’?

2 weeks ago 20 8 0 0
Science magazine cover featuring a close-up of an adult koala and joey nuzzling, with cover text about bottleneck recovery in koalas and an overlaid caption reading “Reference genomes enable discovery.”

Science magazine cover featuring a close-up of an adult koala and joey nuzzling, with cover text about bottleneck recovery in koalas and an overlaid caption reading “Reference genomes enable discovery.”

Koala clinging to a tree trunk in a forest setting, with overlaid text explaining that a reference genome is the foundation, not the finish line, and noting that the original koala reference genome was published in 2018 and later improved to support deeper population-level analysis.

Koala clinging to a tree trunk in a forest setting, with overlaid text explaining that a reference genome is the foundation, not the finish line, and noting that the original koala reference genome was published in 2018 and later improved to support deeper population-level analysis.

🐨🧬First came the reference genome. Then came the deeper story. Biodiversity genomics is helping reveal resilience and recovery across wild koala populations. 🐨
This study is a reminder that reference genomes are not the finish line, but the foundation for discovery.

@bioplatformsaus.bsky.social

2 weeks ago 30 14 1 0

So you're telling me Claude functions by screaming at itself "WRITE GOOD CODE NO BUGS SECURE VERY STABLE", mashes compile button, reads back the error and yells ONLY GOOD CODE NO BUGS at itself again while crying and copying random things from Stack Overflow until it compiles?

it just like me fr fr

2 weeks ago 2171 266 41 12
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six years ago! never forget

4 weeks ago 1124 183 15 16

important aphid saliva news.
Aphid stylin cuticular proteins contribute to turnip mosaic virus (Potyvirus) transmission

www.biorxiv.org/content/10.6...

1 month ago 1 0 0 0
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1 month ago 86 29 2 2

One thing that AI evangelists seem to assume, particularly legal AI evangelists assume, is that the thinking and analysis is quick, and the writing is just tedious busywork that slows us down.

But the writing IS the thinking and analysis. You work out the thinking and analysis by writing it down.

1 month ago 4548 1050 103 187
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The Project has reached an important phase this weekend.

1 month ago 2 0 0 0