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Posts by Patrick Kerstein

Inhibitory neurons are among the most transcriptomically diverse class of neurons in the CNS, with some brain regions having 60+ distinct cell types. Do humans share the same repertoire as rodents? Birds? Fish? 1/13

1 month ago 67 26 3 4
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The 2026 Visual System Development GRC and GRS are fast approaching. Jeremy Kay, Kristen Kwan, Robert Johnston, and I have built an exciting program that we hope you will enjoy. Looking forward to seeing everyone at the meeting this summer in beautiful Maine. Register and RT!

1 month ago 25 15 0 2

Here’s the deal with the FY26 NIH funding bill:

One line in the 1000+ pg bill = significantly less science.

The increase to ~40% of grants moving to MYF is estimated to result in a 35% decrease in the NUMBER of NIH grants funded annually—moving the paylines from 10% to around 4%.

THIS IS BAD.

2 months ago 134 89 6 4

Absolute debasement of academic standards
*student submits opinion in psych class
*gets bad grade
*instructor says she can make whatever arguments she wants but must draw on empirical sources
*student & Turning Point says her religious freedom & first amendment rights violated
*professor suspended

4 months ago 2491 726 76 48

Our Biochemistry department at Purdue has an open tenure-track position as part of a cluster hire in advanced chemistry including drug discovery and biosynthetic pathways: careers.purdue.edu/job/Assistan...

5 months ago 3 1 0 0
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"Humans aren’t very efficient movers—until you put us on a bicycle, when we become some of the most energy-efficient land travelers in the animal kingdom."
www.scientificamerican.com/article/a-hu...

6 months ago 509 146 19 21

Dear funding agencies,

I know we all want to discover the wonder drug that will cure the horrible diseases, but to do that, we need to invest in basic, unsexy, foundational research on how the systems work. Funding can’t all be drug development.

Sincerely,
Looking for basic research grants.

6 months ago 2300 388 43 13
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Genetic tuning of retinal ganglion cell subtype identity to drive visual behavior Nature Communications - This study reveals that graded expression of the transcription factor BRN3B fine-tunes the identity and function of melanopsin-expressing ipRGC subtypes in the retina....

Our paper is out today! In @tiffmschmidt.bsky.social lab, we identified a single transcription factor, BRN3B, that shapes multiple, key features that define diverse ipRGC subtypes🧬👁️🐭

6 months ago 31 7 7 1
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Basic Science Is The Foundation Of Future Cures Injecting partisan politics into American basic science would be terrible for the US: for the economy, and for development of future treatments for diseases like schizophrenia and Alzheimer's.

That view is exceptionally naive.

As @narosenblum.bsky.social and I wrote last fall, “basic scientific research [is] a long-term investment, one that only governments have the time horizon to make, and it brings enormous payoffs.”

It can’t just be moonshots and looking for unicorn behemoths.

7 months ago 257 60 6 3
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Tenure-Track Positions in Functional Genomics/Genetics and Systems Biology - Office of the Dean of the Faculty - Reed College

Come be my colleague! We are hiring for two tenure-track positions. www.reed.edu/dean_of_facu...

7 months ago 25 26 0 1

Thanks!

8 months ago 1 0 0 0

Paper submitted! Preprint to come.

8 months ago 4 0 1 0
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Purdue student detained by ICE and taken to troubled Louisiana holding facility Yeonsoo Go, 20, was detained after her immigration hearing in Manhattan and taken away by ICE agents.

Go, a college student, has a dependent visa (her mother, an Episcopal minister, is here on a religious worker visa), which doesn't expire until Dec. But when she tried to renew it early, ICE nabbed her and sent her halfway across the US to a detention center.
www.wthr.com/article/news...

8 months ago 3215 1617 89 170
Assistant Professor Job Title Assistant Professor Department Biology Department Worker Type Regular Pay Type Salary Salary will be commensurate with the level of the position, education, and experience. Benefit Eligible ...

Miami is hiring a neurobiologist! I am excited to welcome a new colleague to our Neuroscience community! Please share!

miamioh.wd5.myworkdayjobs.com/en-US/miamio...

8 months ago 40 37 0 2

Reminder! Tenure track position in Genetics at Trinity College Dublin! Come join us, we're nice... 😊 Please repost! 🙏

8 months ago 15 21 0 1
Assistant Professor of Neuroscience and Behavior Job no: R-0000002388 Position Title: Assistant Professor of Neuroscience and Behavior Work Type: Faculty Full time In-Person Start Date: 07/01/2026 Job Description: The Department of Neuroscience and ...

Mount Holyoke College in lovely western Massachusetts is hiring a tenure-track neuroscientist. Amazing students and fantastic faculty support - please share!
mtholyoke.wd5.myworkdayjobs.com/en-US/Extern...

8 months ago 79 82 1 6
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Hi all, we got a grant for a cool project that will follow up of our paper published a few months ago (see below). We will explore how light acts as a morphogen to instruct PCP. If you are looking for a postdoc position and interested in this topic, please reach out!

8 months ago 26 15 0 0
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Quality of scientific papers questioned as academics ‘overwhelmed’ by the millions published Widespread mockery of AI-generated rat with giant penis in one paper brings problem to public attention

Quality of scientific papers questioned as academics ‘overwhelmed’ by the millions published
Widespread mockery of AI-generated rat with giant penis in one paper brings problem to public attention
@iansample.bsky.social writes @theguardian.com
www.theguardian.com/science/2025...

9 months ago 41 16 3 2

Got stunning fluorescence microscopy images? 🌈🔬 SDB wants to feature YOUR work for #FluorescenceFriday! We highlight images from SDB members with a short description and the image creators 📸. Fill out the form to be featured: docs.google.com/forms/d/e/1F...

9 months ago 8 3 0 0

I think a lot of people don’t realize how hard it is to get approval to work on animals in the first place. You have to have a clear & well-researched justification for every experiment. You have to fully explain why there is no other way to address the question without animals 1/

9 months ago 22 6 1 0
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“Why Are We Funding This?” Long-standing myths about “silly science” have contributed to the reckless slashing of government-supported research.

My latest for American Scientist Magazine helps give scientists the tools to fight back against politicized charges that our research is silly or pointless- tools that will work whether you’re asked “why are we funding this” from your asshole uncle at Thanksgiving or an asshole US Senator.
🧪🌎

10 months ago 1054 548 34 36

Given the SCOTUS ruling yesterday, it's seems possible....even highly likely....that the NIH IDC ruling will now only apply to the states that filed. If you're in a red state, that means 15% IDCs might be a reality soon.

9 months ago 12 8 6 0
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Former DOGE engineer says federal waste and fraud were 'relatively nonexistent' NPR's Juana Summers talks with Sahil Lavingia, who worked for the Department of Government Efficiency as a software engineer assigned to the Department of Veterans Affairs, about his experience.

“I personally was pretty surprised, actually, at how efficient the government was,” Sahil Lavingia told NPR's Juana Summers.

9 months ago 7350 2849 224 349
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This is worse than many appreciate because it is not merely a delay. Many institutions such as mine are TERMINATING these otherwise active grants if the NoA is delayed by more than a month because they cannot afford to keep the grant supported personnel on payroll

10 months ago 31 25 4 1
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We set out to quantify U.S. academic contributions to medicines. The results stunned even us From 2020 to 2024, universities contributed patents underpinning 50% of FDA-approved drugs. 87% of those academic breakthroughs came from American institutions.

A study finds, US based academic research institutes account for 50% of new medical drugs in the last 4 years. 🧪

www.statnews.com/2025/06/06/u...

#science #savescience #stat

10 months ago 235 113 3 15

Yeah! Congrats!

10 months ago 0 0 0 0
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Distinct functional domains of Dystroglycan regulate inhibitory synapse formation and maintenance in cerebellar Purkinje cells Communications Biology - Genetic manipulation of functional domains on Dystroglycan reveals distinct developmental roles in inhibitory synapse formation and maintenance in cerebellar cortex.

www.nature.com/articles/s42...

10 months ago 24 6 2 0

must be incredibly frustrating and disheartening to have federal funding that was promised to you for important work suddenly and arbitrarily ripped away

10 months ago 35219 8107 612 253
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A Review of the President’s Fiscal Year 2026 Budget Request for the National Institutes of Health | United States Senate Committee on Appropriations United States Senate Committee on Appropriations

Senate hearing on the FY26 NIH budget with Jay Bhattacharya
June 10, 10am ET
www.appropriations.senate.gov/hearings/a-r...

10 months ago 69 47 0 3