Advertisement · 728 × 90

Posts by Laura Gutiérrez-Miranda

Post image

Dr. Jane made an indelible mark on our understanding of chimpanzees and other species, and also of humankind and the environments we all share.

She inspired curiosity, hope, and compassion in countless people, and paved the way for many others.

#ThankYouJane #RememberingJane

Photo: Marko Zlousic

6 months ago 348 139 19 32
Post image

Bassi et al. @karinayaniv.bsky.social @weizmanninstitute.bsky.social use #zebrafish to help identify new treatments for a severe lymphatic malformation. rupress.org/jem/article/...

#CardiovascularBiology #HumanDiseaseGenetics

8 months ago 1 1 0 1

My Bioinformatics Bootcamp turned blog! Enjoy this collection of free #zebrafish resources, now posted on @the-node.bsky.social. While not comprehensive, it gives an assortment of cools tools available to researchers. Feedback would be appreciated! thenode.biologists.com/bioinformati...

11 months ago 23 7 3 3

And just like that we get another #zebrafish surprise !
@pina85.bsky.social work introduces the Inferior Vena Cava vascular remodelling in zebrafish 🦓🐟
Congratulations to all the team for this beautiful story 👏🏻🍾

11 months ago 3 0 1 0
Post image

And that is a wrap! Great success of the first European #Lymphatic Symposium
Next one: Budapest 2027

11 months ago 5 1 0 0
Preview
The axillary lymphoid organ is an external, experimentally accessible immune organ in the zebrafish This work describes a previously uncharacterized external, experimentally accessible secondary lymphoid organ in the zebrafish located above the pectoral f

Axillary lymphoid organ in #zebrafish
🤩
rupress.org/jem/article/...

1 year ago 2 0 0 0

Do not miss it! ⬇️
@ivanbassi.bsky.social will present his latest project 🐟 #zebrafish

1 year ago 3 2 0 0
Post image

🤩 Excited to share our protocol for computationally averaging confocal images of zebrafish lymphatic vessels to identify phenotypes! 🐟🔬 Check it out in Star Protocols 👉 star-protocols.cell.com/protocols/4030

#Zebrafish #Microscopy #StarProtocols

1 year ago 10 2 0 1

Not sure exactly what is going on but I have also received this message today at times where traffic should be rather low 😅
So just to be on the safe side here...Does anybody know if there is a mirror page or alternatives in case one of these days NCBI page is gone? 💨

1 year ago 1 1 1 0
Preview
Generation of functional oocytes from male mice in vitro - Nature Mouse induced pluripotent stem cells derived from differentiated fibroblasts could be converted from male (XY) to female (XX), resulting in cells that could form oocytes and give rise to offspring aft...

Generation of functional oocytes from male mice🤯
www.nature.com/articles/s41...

1 year ago 1 0 0 0
Advertisement

Useful new tool, for those finterested!

1 year ago 6 1 0 0

Same here! We can only wait and cross fingers for Rita Fior's lab and all the team at Champalimaud 🤞🏻

1 year ago 2 0 0 0
Preview
Fish implanted with tumor cells could help oncologists quickly personalize cancer treatments The first clinical trial of zebrafish embryos acting as cancer “avatars” will start soon

The first oncology clinical trial using #zebrafish avatars will start this month in Portugal. It is definitely not an easy task. But if it works, it will be a great predictive tool 💪🏻 Good luck!
www.science.org/content/arti...

1 year ago 9 1 1 1
Repurposing of a gill gene regulatory program for outer ear evolution - Nature Nature - Repurposing of a gill gene regulatory program for outer ear evolution

www.nature.com/articles/s41...

1 year ago 0 0 0 0
Preview
Direct specification of lymphatic endothelium from mesenchymal progenitors - Nature Cardiovascular Research Lupu, Grainger, Kirschnick et al. show that, contrary to prevailing belief, the initial specification of mammalian lymphatic endothelial cells primarily occurs from previously unidentified mesenchymal...

www.nature.com/articles/s44...

1 year ago 3 0 0 0
Preview
Deep-Tissue Spatial Omics: Imaging Whole-Embryo Transcriptomics and Subcellular Structures at High Spatial Resolution The inherent limitations of fluorescence microscopy, notably the restricted number of color channels, have long constrained comprehensive spatial analysis in biological specimens. Here, we introduce c...

The only #resolution I want for the new year 😅
www.biorxiv.org/content/10.1...
#microscopy

1 year ago 1 0 0 0
Preview
Comparing cooperative geometric puzzle solving in ants versus humans | PNAS Biological ensembles use collective intelligence to tackle challenges together, but suboptimal coordination can undermine the effectiveness of grou...

I remember doing the ant maze as a lab activity few years ago...and with no communication among the members allowed...it was not so easy 😅
www.pnas.org/doi/10.1073/...

1 year ago 1 0 0 0
Figure showing that IBEX can be used to simultaneously label all major retinal types in zebrafish embryos, including confocal images and schematics indicating the labelled cell types. The confocal images show zebrafish retinas labelled with DAPI and 11 different markers: Ribeye-A (dark blue), carbonic anhydrase (CA1, purple), glutamine synthetase (GS, red), PKC-β (green), Zrf-1 (cyan), HuC/D (orange), GFP transgene (yellow), calbindin (CalB, magenta), peripherin-2 (PRPH2, light blue), GNAT2 (orange) and RLBP1 (pink).

Figure showing that IBEX can be used to simultaneously label all major retinal types in zebrafish embryos, including confocal images and schematics indicating the labelled cell types. The confocal images show zebrafish retinas labelled with DAPI and 11 different markers: Ribeye-A (dark blue), carbonic anhydrase (CA1, purple), glutamine synthetase (GS, red), PKC-β (green), Zrf-1 (cyan), HuC/D (orange), GFP transgene (yellow), calbindin (CalB, magenta), peripherin-2 (PRPH2, light blue), GNAT2 (orange) and RLBP1 (pink).

Aanandita Kothurkar, @colinchulab.bsky.social, Ryan MacDonald and colleagues @ucleye.bsky.social apply IBEX to simultaneously identify all the major retinal cell types.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...

1 year ago 57 19 1 4
Advertisement

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock-ins www.biorxiv.org/content/10.1101/2024.12....

1 year ago 6 3 0 1

Help support ZFIN and other MODs by signing this open letter 🙏 🧪

1 year ago 8 4 0 0
Figure 1 (A) Larval expression of vegfc:EGFP (green) and kdrl:DsRed (magenta) lines in a 2 dpf live fish. Scale bar: 200 µm. (B) Confocal images showing vegfc:EGFP (green) and kdrl:DsRed (magenta) expression in the trunk at 2 dpf. A single-channel image of vegfc:EGFP expression is shown in grayscale on the right. Scale bar: 100 µm. (C,D) Whole-mount images (maximum projections of z-stacks) of the ventricular surface showing expression of vegfc:EGFP (green) and flt1:tdTomato (magenta) at 5 wpf (C) or 8-9 wpf (D). Single-channel images of vegfc:EGFP expression are shown in grayscale on the right. The framed regions are enlarged beneath. The arrows indicate EGFP+tdTpmato+ arteries. Scale bars: 100 µm.

Figure 1 (A) Larval expression of vegfc:EGFP (green) and kdrl:DsRed (magenta) lines in a 2 dpf live fish. Scale bar: 200 µm. (B) Confocal images showing vegfc:EGFP (green) and kdrl:DsRed (magenta) expression in the trunk at 2 dpf. A single-channel image of vegfc:EGFP expression is shown in grayscale on the right. Scale bar: 100 µm. (C,D) Whole-mount images (maximum projections of z-stacks) of the ventricular surface showing expression of vegfc:EGFP (green) and flt1:tdTomato (magenta) at 5 wpf (C) or 8-9 wpf (D). Single-channel images of vegfc:EGFP expression are shown in grayscale on the right. The framed regions are enlarged beneath. The arrows indicate EGFP+tdTpmato+ arteries. Scale bars: 100 µm.

Differential vegfc expression dictates lymphatic response during zebrafish heart development and regeneration

Read this Research Article by Sierra Duca, Yu Xia, Michael R. M. Harrison, Jingli Cao and colleagues:
https://buff.ly/49hhwIf

1 year ago 21 7 1 1

Amazing work really, congratulations!!

1 year ago 0 0 0 0

New study on clonal fate during mouse #embryogenesis using in vivo lineage tracing+ deep learning 🤯👏🏻👏🏻

1 year ago 2 0 1 0
Post image

Bone remodeling is traditionally driven by osteoblasts and osteoclasts, but our study reveals a third essential player: "Type R capillaries". 🦴🔬😍

Excited to share my PhD work from Ralf H. Adams lab, now published in @natureportfolio.bsky.social Nature Cell Biology.

www.nature.com/articles/s41...

1 year ago 34 8 1 1

I would like to be added please 🙋🏻‍♀️

1 year ago 1 0 0 0
Advertisement
Preview
Cell state transitions are decoupled from cell division during early embryo development - Nature Cell Biology Kukreja et al. show that blocking cell division in zebrafish does not affect differentiation of major cell types during gastrulation and segmentation, but it does decelerate differentiation of particu...

Cell division is dispensable for cell differentiation during early development although it delays the differentiation rate of some cell types ⏳. www.nature.com/articles/s41...

1 year ago 5 0 0 0
An organotypic atlas of human vascular cells - Nature Medicine A vascular cell atlas integrating single-cell data of 19 organs and tissues from 62 donors identifies angiotypic and organotypic characteristics of endothelial and mural cells.

Vascular Thanksgiving 🙏🏻
www.nature.com/articles/s41...

1 year ago 5 1 0 0

The fat remembers: a scientific explanation to the yo-yo effect 🪀

1 year ago 0 0 0 0
Microscopy Training Grants
Supporting microscopy training for early-career researchers in cell biology 

Apply for a grant of up to £1000

Journal of Cell Science FocalPlane

Microscopy Training Grants Supporting microscopy training for early-career researchers in cell biology Apply for a grant of up to £1000 Journal of Cell Science FocalPlane

Are you an #ECR who would like to attend a #microscopy or #bioimageanalysis training course in the next ~6 months but don't have sufficient funding, check to see if you are eligible for our JCS-FocalPlane Training Grant.

Next deadline: 22 November 2024

www.biologists.com/grants/jcs-f...

1 year ago 42 39 0 3