Genetically modified pig liver keeps man alive until human organ transplant First time the procedure has been performed on a living person.

🤓Read all about it: www.nature.com/articles/d41...

👏We are pleased to report the man is doing well.

🇭🇺Hungary just voted out its authoritarian prime minister of 16 years, and did it with an 80% voter turnout powered by Gen Z.

🫢Missed this story?

🎙️TPN exec. director Emma Varvaloucas breaks it down.

play.megaphone.fm/6m_tpqauqo-o...

Federal Agency Unveils Three Potential Osteoarthritis Treatments

😮Three teams have regrown bone and cartilage, even entire knees, in mice, rats, and rabbits.

🦵Large animal trials, followed by human ones, are next.

👏The eventual goal is a cure for osteoarthritis.

www.nytimes.com/2026/04/06/h...

Greenhouse gas emissions in Japan fell to record low in fiscal 2024 In fiscal 2024, emissions in Japan were down 28.7% from fiscal 2013 and the amount of carbon dioxide released slipped below 1 billion tons for the first time since then.

What happened?
🏭CO2 emissions from industries declined 2.5%
🏠Households fell 0.7%
⛴️The transport sector saw emissions drop 1.6% thanks to improved fuel efficiency in freight shipments.

🤔What's next?

🎯The government aims to reach carbon neutrality by 2050.

www.japantimes.co.jp/environment/...

🇯🇵📉The Daily Dose via @japantimes.co.jp 🇯🇵📉

According to the Environment Ministry, Japan's greenhouse emissions are at a record low, having fallen by 1.9% in FY 2024.

There’s a type of breast tissue that can hide cancer. Here’s what to know about it. An interview on dense breast tissue. Plus: What’s a “formulary”? + What rights do you have to your medical records?

🤓To read more about it check out Doing Well's excellent article. doingwellnews.substack.com/p/dense-brea...

🥭It's time to talk about the density of, to quote the modern philosophers the Black Eyed Peas, "lady lumps."

Do we need a NEW America? | with Anne-Marie Slaughter What do we do when our systems stop working? Anne-Marie Slaughter, the CEO of New America, former Director of Policy Planning at the U.S. State Department under Secretary Hillary Clinton, and one of t...

"I still fundamentally believe that the human spirit is best served by a form of self-government that is fair and equal and representative, and I have not seen anything in the past or the present to convince me otherwise," says the CEO of @newamerica.org, @slaughteram.bsky.social.

🤠3 Things That Went Right This Week🤠
🇹🇭 Thailand has formally criminalized sexual harassment, including online
🐙More than 10% of the world’s oceans are now protected, a milestone
📉 Rents are falling across the US. (Yes, you read that right.)
👇Need more? Read on!
theprogressnetwork.org/hungary-elec...

Global democracy is in better shape than you think EIU’s annual index suggests an end to the democracy recession

👏Which improved the most last year?

🇨🇦Canada rose five places to ninth after its highest election turnout in over 30 years.

www.economist.com/interactive/...

🤔Is there more good news?

⬆️Yes, the global index rose by 0.02 points—one of the biggest increases since 2012.

🧐What country is the most democratic?
🇳🇴Norway

😨What country is the least?
🇦🇫Afghanistan

🗳️🌏The Daily Dose via The Economist 🗳️🌏

According to the EIU's Democracy Index 2025, two-thirds of the world's countries either held steady or improved their democracies last year.

🤔What do we do when our systems stop working?

🎙️TPN founder Zachary Karabell joins @slaughteram.bsky.social, the CEO of @newamerica.org , to reckon with a country in the middle of a massive realignment.

🎧Listen to the full episode of What Could Go Right? play.megaphone.fm/f1gmpnxyryun...

⤴️ Does 'Project Hail Mary' help Project Up Wing? After two decades of cinematic doom, audiences are ready for heroes who do the math. More of this please, Hollywood

"Independence Day, Armageddon, Deep Impact—the odds were against us, but the basic path to victory was consistent: humanity, given sufficient coordination and ingenuity, could win. That confidence mirrored the decade."

fasterplease.substack.com/p/does-proje...

"The blockbusters of the 1990s treated existential threats as invitations for heroism," writes TPN member @jamespethokoukis.bsky.social.

10% of the ocean now protected. We have four years to triple it - Oceanographic Over 10% of the global ocean is now officially protected. But with coverage needing to triple by 2030, the hard work is only just beginning.

🤔How much of the ocean is that?
🤏About 10%

🎯What's the new goal?

🧐Under the Kunming-Montreal Global Biodiversity Framework, governments collectively committed to protecting 30% of the Earth’s land and seas by 2030.

😬So they have to triple that amount in the next four years.

🌊🦑The Daily Dose via @oceanographicmag.bsky.social 🦑🌊

Over the past two years, five million square kilometers of ocean have been protected.

That's an area larger than the EU.

🚀The Artemis II crew has just gone deeper into space than any other humans, but do you remember how hard it was to get there in the first place?

Tyler Cowen: Progress, Classical Liberalism, and the New Right

"There’s no serious comparison. And I don’t just mean life expectancy, just actual life crime rates, what you could afford to buy, how much you could travel. Again, it’s not close."

humanprogress.org/tyler-cowen-...

"In the 1970s, I lived in. It was fun, but it was much worse than today," says TPN member Tyler Cowen to Marian Tupy for @humanprogress.bsky.social.

Vingroup launches first bullet train project linking Vietnamese cities Max 350 kph trains to connect Hanoi to factory and travel hotspots in one-quarter the time

🇻🇳Vietnam is getting its first bullet train!

⛏️Vingroup broke ground this week on a high-speed railway project that aims to connect passengers from Hanoi to Bac Ninh, Hai Phong, and Quang Ninh by the end of 2028.

asia.nikkei.com/business/tra...

Teen birth rates hit another historical low in 2025, CDC says The teen birth rate continues its decades-long downward trend. Researchers say many factors are at play, including less sexual activity and more access to contraception and abortion.

🧐How come?

🧮Many factors including:
👉Lower rates of teen pregnancy overall
👉Higher use of contraception
👉Lower rates of sexual activity

www.npr.org/2026/04/09/n...

📉🇺🇸The Daily Dose via @npr.org 📉🇺🇸

According to a report published by the National Center for Health Statistics, teenage births dropped in the US by 7% between 2024 and 2025, bringing them to a record low.

Arthur Brooks: Don’t Waste Your Suffering The modern fixation on a suffering-free life has left us fragile, anxious, and unfulfilled.

"Every life has a lot of suffering, it’s true. You can live your years just getting through it, in which case you will still suffer but you won’t learn and grow," writes TPN member Arthur Brooks.

Fentanyl Vaccine Begins Trial in New Effort to Prevent Overdose Biotech startup ARMR Sciences Inc. said it has begun a human trial of its anti-fentanyl vaccine in an early study that could one day lead to a inoculation offering months-long protection from the dead...

💉The first trial for an anti-fentanyl vaccine has begun, in an attempt to stimulate the production of antibodies against the controlled substance that would prevent it from shutting down the breathing process.

The global suicide rate has fallen since the 1990s, but the death toll is still high Even after years of working with global health data, one statistic that I’m always struck by is the number of people who die by suicide every year. In 2023, it was estimated to be around three-quarter...

Read all about it:
ourworldindata.org/data-insight...

🌏📉The Daily Dose via @ourworldindata.org 📉🌏

The global suicide rate has fallen 40% since the 1990s.

Read all about it: edition.cnn.com/2026/04/05/u...

Colorado is the first state to ban arrests based on the results of a common drug test that is quick, but notoriously unreliable.