A proteostasis clock underlies the timing of bacterial dormancy and antibiotic tolerance www.biorxiv.org/content/10.6... #jcampubs
Posts by Chuankai Cheng
(bacterial) chromosome segregationists take note 👇
membrane-anchoring of the 𝘰𝘳𝘪𝘊 region to ensure proper daughter chromosome segregation after replication initiation – proposed decades ago but never substantiated... 👉now shown for 𝘚. 𝘢𝘶𝘳𝘦𝘶𝘴 by mariana pinho's lab
10 years of massive Asgard undertaking, masterly summarized!
😱😱😱😱😰I am so sorry about this!
Diversity, ecology, cell biology and evolution of the Asgard archaea www.nature.com/articles/s41... #jcampubs
Great to see this amazing resource finally published !
MicrobeAtlas - 2.4 million SSU rRNA gene sequence datasets systematically analysed against an extensive full length reference database enabling tracking of OTUs at global scales!
www.cell.com/cell/fulltex...
Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate www.nature.com/articles/s41... #jcampubs
We are thrilled to announce the newest study from our lab (and great collaborators) is out now in @nature.com
We show that #coral #microbes are untapped "biosynthetic reservoirs", full of unique
natural products.
doi.org/10.1038/s415...
By combining the ecological and evolutionary analyses, we present a Heimdallarchaeia-centric model for the origin of eukaryotes, based on our expanded genomic catalogue. #eukaryogenesis
9/12
Objective method to estimate the duration of the DNA replication cycle without perturbation in Escherichia coli www.biorxiv.org/content/10.6... #jcampubs
Today, I would like to honor the memory of Roger Y. Tsien, born on February 1, 1952. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday
www.nature.com/articles/nme...
Thank you so much Paul! Your pivotal work 10 years(!) ago has been truly inspiring! I am now a huge advocate for projects like “what could we learn about the microbes by trying to cultivate them well”🙌.
Most importantly! Thanks a lot team! @greenwoodbritt.bsky.social , Pratixa, @hasrari.bsky.social , Carmen, Kate and Rui👏
The 2020 lockdown has steered me towards thinking a lot about the flow cytometry, as this was the only lab equipment that I mastered by then. It is a special experience that on the day my paper launches, I am at UTMSI helping @suleles.bsky.social set up the new flow cytometry (and meet cute Maya!).
I learned more about the potential of flow cytometry. It is not just for counting the cells, it could infer the number of chromosomes of each cell (ploidy level) by the fluorescence signals! This is how later we focused a lot on the ploidy level distributions across different conditions.
In late 2019, I got some solid training from @aquaticmicrolab.bsky.social @vclanclos.bsky.social and Jordan about bacterial liquid culture set up and using the flow cytometry to enumerate cells. Then 2020 was here🥹, the lockdown forced me to think about how to leverage the technique I learned.
Coming from a computational background with and aspiring to do experiments, it was the trust and support from @jcamthrash.bsky.social that brought me into this nice project.
This paper originated from a simple idea: Since we want to study SAR11 growth physiology, let’s look at how one SAR11 bacterium becomes two SAR11 bacteria, inspired by the quote from François Jacob, “The dream of a bacterium: to produce two bacteria”.
It has been such a long journey! It feels somehow surreal that in 2020 I barely knew about bacterial cultivation and flow cytometry🥹.
Funded postdoc + PhD opportunities in marine microbial ecology! Please share with folks that might be interested.
Start date is flexible (fall 2025 to summer 2026)
More about the lab + applying (Postdoc rolling, PhD apps due Oct/Jan):
sites.google.com/uncc.edu/mic...
Bacterial symbionts enjoy their seasonal produce! Our new work shows how chemosynthetic symbionts adjust their energy sources during seasonal upwelling in the Tropical Eastern Pacific, highlighting the resilience of animal-microbe partnerships to environmental change journals.asm.org/doi/10.1128/...
Hey Tyler! Thank you so much for such a supportive comment! Yea I will be doing a lot of extractions over the summer to get gene expression data💪.
Carini Lab at ASM
Adriana’s talk
Caitlin’s talk
So proud of our student’s presentations at #ASMicrobe. Great to meet a bunch of new folks and talk shop with friends.
See you all again soon!
@astrobio-agb.bsky.social @oceancait.bsky.social
Hope to see all new and old faces🥳
Hey all - check this post if you’re at #ASMicrobe this weekend.
Let’s have a meet up tomorrow for a photo op of microbiologists on @bsky.app who are at #ASMicrobe!
Be there at 3 PM at the main entrance giant ASM sign!
In person meetups are super fun - please be there!
And plz repost!
👋
My talk at #ASMicrobe ! Looking forward to this!
Our latest, and a tour de force by postdoc Brittany Bennett!
Polyhydroxybutyrate production in freshwater SAR11 (LD12) www.biorxiv.org/content/10.1...
Another genome resource from our collection- a very common freshwater bacterial group that has very few published genomes:
Draft genome sequence of the BAL58 Betaproteobacteria representative strain LSUCC0117 journals.asm.org/doi/10.1128/... #jcampubs