Ex-BCG leader & David Sinclair’s COO on why evolution created aging & how to cure it -Michael Ringel YouTube video by Free Radicals

Check out the Free Radicals podcast by Daniel Shur and Eric Dai. They ask hard questions: youtu.be/pCwPH8iN1F0

And we know that the components (nucelotides) of a molecule now demonstrated to be self-replicating (RNA) form abiotically... increasing the odds (but of course not guaranteeing) that alien life may have some similarities in overall biochemistry.

All of these are probabilistic, and there could be life that doesn't fit any of this: silicon-based that evolved on surfaces or in clouds. But a) it would be even more rare, and b) we'd be even less clear about knowing it when we see it

I think there's a pretty strong inference to say likely carbon-based: it is the abundant element that can have complex chemistry. And a pretty strong inference to say liquid medium (biochemistry very hard in gas and solid). There are alternatives like methane, but they're not very good at dissolving

What font will you use?

Fish form follows function. Thick body/tail=efficient thrust- like a launching rocket- good for filtering a wide area (top left). Small fins at all angles=moving in any direction- like a docking spacecraft- good for searching in nooks (bottom right). Webb, Amer Zool 1984.

Your baseball team is from a midsized city that punches well above its weight in all kinds of innovation and progress. Your arch-rival is from the nation's largest, most powerful city and always has an extremely well-funded team. Nearly 100 years ago, you traded your best player (Babe Ruth)

Bridging Ethics, Science, and Practical Longevity YouTube video by Longevity.Technology

Is #geroscience and #longevity for everyone, or just for a few? Podcast on the ethics of it all, with @agingdoc.bsky.social and Carolyn Ringel: www.youtube.com/watch?v=Tedu...

Beautiful animal!

Life Biosciences Announces FDA Clearance of IND Application for ER-100 in Optic Neuropathies IND clearance marks the first ever cellular rejuvenation therapy using partial epigenetic reprogramming to reach human clinical trials BOSTON, January 28, 2026 – Life Biosciences, Inc., (“Life Bio”) a...

@lifebiosciences.bsky.social, founded by @davidsinclairphd.bsky.social & Tristan Edwards, helmed by CEO Jerry McLaughlin, has received @fda.gov IND clearance for cellular rejuvenation using partial epigenetic reprogramming in optic neuropathies. I'm so proud: www.lifebiosciences.com/life-bioscie...

Possibly how they constructed them?

Longevity biotech now targets root causes rather than single diseases. This is a paradigm shift in medicine

Ocean Warming Breaks Record for Ninth Straight Year - Inside Climate News Every second of last year, the Earth’s oceans absorbed the equivalent in energy to 12 Hiroshima-sized atomic bombs.  Global ocean heat content (OHC) increased for the ninth consecutive year in 2025, a...

Ocean Warming Breaks Record for Ninth Straight Year insideclimatenews.org/news/0901202...

Including some species, like many bacteria, hydra, planaria, and the "immortal" jellyfish that do not age at all.

Why do we age? A detailed look at the data shows only one theory that matches observation: onlinelibrary.wiley.com/doi/epdf/10....

Was at #Longevity #Biotech Association meeting. A rising tide lifts all boats, and it is so great to be able to work with colleagues at other companies on this. Thank you to James Peyer, Jim Mellon, @nirbarzilaimd.bsky.social , and especially @risastarr.bsky.social for pulling this together.

Interested in #longevity #biopharma? In Nat Aging, Lim, Zhang of @b-c-g.bsky.social and I quantify increasing activity in therapeutics using #aging biology. Soon, @lifebiosciences.bsky.social will be the first in clinical trials on a cellular rejuvenation therapy: www.nature.com/articles/s43...

I spoke at #transvisionmadrid today courtesy of Jose Luis Cordeiro. If you aren't signed up, there's still time to catch the remainder of the program, in person or online.

The inimitable @peterdiamandis.bsky.social is a tornado of thought and action. His track record is unmatched, as is his passion for longevity biotech. At @lifebiosciences.bsky.social we’re excited to contribute with our upcoming first-in-human cellular regeneration trials, planned for Q1 2026.

The Longevity Paradox: Why We Don’t Plan for Healthy Aging Before It’s Too Late A new era of personalized care can add trillions in economic value by keeping people active, productive, and independent longer.

Congrats to my ex-BCG colleagues for publishing "The Longevity Paradox". Great insights on how much people care about their health and longevity, but are often at a loss as to how to proceed... with tips on what to do about it! www.bcg.com/publications...

Martian Baby

Bit of an homage to this style of music, an interspecies love song called "Martian Baby": open.spotify.com/track/2mcRuK...

I think Rafa would have preferred Senescence Los Angeles Meeting.

Pantsuit

It's not the end: open.spotify.com/track/1H4AN0...

#totocat is at it again. #cat #toto #funnycat #catvideo #catmemes @totototoilet.bsky.social @weirdlilguys.bsky.social

PanelPicker | SXSW Conference & Festivals PanelPicker® is the official SXSW user-generated session proposal platform. Enter ideas and vote to help shape Conference programming for SXSW and SXSW EDU.

@davidsinclairphd.bsky.social and I would like to share with you at #SWSX the science, ethics, and economics of #longevity science and cellular #rejuvenation. But we need your help: vote *this week* for our session at participate.sxsw.com/flow/sxsw/sx... if you want to hear more about this!

When your #cat gets bored and discovers the #toto bidet... hours of fun. #funnycat #catvideo #catmemes @totototoilet.bsky.social @weirdlilguys.bsky.social

Single for August by our after-work band, Abacus Rings, is out: Further Up and Further In. Available all platforms and at this link: ditto.fm/further-up-a...

That's a healthy menu, although I notice the "cake" gets a special color...

Great speakers!

New single out by our after-work band Abacus Rings: "Something". Carolyn Ringel's favorite, maybe because she thinks it is about her. Available on all platforms, and here: ditto.fm/something-ab...