Exclusive: Key US infectious-diseases centre to drop pandemic preparation Staff members have been instructed to scrub this topic and ‘biodefense’ from the agency’s website.

Scoop: The NIH infectious-diseases institute (NIAID) will soon scrub “pandemic preparedness” and “biodefense” from its web pages, according to e-mails I obtained.

The directive is the start of a broader shake-up at NIAID, which has long been attacked by Republicans.

Kinderwunsch: 70 Prozent IVF scheitern – diese Labor‑Entdeckung könnte alles ändern | NANO Forschung macht sichtbar, was in den ersten Tagen nach der Befruchtung passiert – der Zeitraum, in dem sich so viele Embryonen nicht einnisten.

Zum aktuellen Ausbruch des Nipah-Virus ordnet das Wissenschaftsmagazin nano die Lage ein und gibt Einblicke in die Forschung im Hochsicherheitslabor von Alexandra Kupke an der Philipps-Universität Marburg. (CR)

Beitrag ab Minute 16:40:
www.3sat.de/wissen/nano/...

Hessen: Sparzwang durch Hochschulpakt: Hier setzen die Unis den Rotstift an Die ersten hessischen Unis haben nach dem Hochschulpakt konkrete Sparpläne beschlossen. Es zeigt sich: Die Mittelkürzungen des Landes sorgen für gravierende Einschnitte, die nach Angaben der Unis letz...

10% weniger für die hessischen Unis. Bei 14 Universitäten heisst das, dass Hessen fast eine Uni einsparen will...

"Nun stehen teure Labore leer, in denen für Deutschlands Zukunft geforscht werden könnte"

www.tagesschau.de/inland/regio...

Tedros Adhanom Ghebreyesus on X: "#Ethiopia has confirmed the outbreak that has infected at least 9 people in the south of the country is of #Marburg virus disease. I commend Ethiopia’s @FMoHealth for its rapid and transparent response to the outbreak, and the work of the Ethiopia Public Health Institute and" / X #Ethiopia has confirmed the outbreak that has infected at least 9 people in the south of the country is of #Marburg virus disease. I commend Ethiopia’s @FMoHealth for its rapid and transparent response to the outbreak, and the work of the Ethiopia Public Health Institute and

The outbreak in Ethiopia is #Marburg virus, the first such outbreak for this country. 9 cases so far, including some health workers. x.com/drtedros/sta...

Ebola Cases Rise as Authorities Race to Contain Congo Outbreak, Health Agency Says Cases have more than doubled in a week

Ebola cases have more than doubled in a week in the Democratic Republic of Congo. Suspected cases increased from 28-68 in recent days, the Africa Centers for Disease Control & Prevention said during an online briefing. Ebola virus has also spread from 2-4 districts. The death toll stands at 16👇

Democratic Republic of the Congo declares Ebola virus disease outbreak in Kasai Province Kinshasa – Health authorities in the Democratic Republic of the Congo have declared an outbreak of Ebola virus disease in Kasai Province where 28 suspected cases and 15 deaths, including four health w...

"The country has a stockpile of treatments, as well as 2000 doses of the Ervebo Ebola vaccine, effective to protect against this type of Ebola, already prepositioned in Kinshasa that will be quickly moved to Kasai to vaccinate contacts and frontline health workers."

www.afro.who.int/countries/de...

We‘re looking for a (Full time) PostDoc at the Institute for Virology at Marburg University to help us with our project about the development of Ebola Virus antivirals. Please apply especially of you are interested in or experienced with BSL4 work: stellenangebote.uni-marburg.de/jobposting/6...

Wie werden aus wissenschaftlichen Erkenntnissen neue Therapien? Was genau passiert, wenn Forschungsergebnisse zu Innovationen in Prävention & Diagnostik werden?

📺 Tauchen Sie ein in die Welt der Infektionsforschung – hier geht's zum Film in voller Länge: t1p.de/DZIF-Film

#GemeinsamgegenInfektionen

📢 #𝗦𝘁𝗲𝗹𝗹𝗲𝗳𝗿𝗲𝗶 Das Deutsche Zentrum für Infektionsforschung sucht eine:n wissenschaftliche:n Projektmanager:in für ein spannendes, EU-gefördertes Projekt zur Pandemiebereitschaft in Europa mit dem Fokus auf Impfstoffe.

➡️ Weitere Informationen und Bewerbung: www.dzif.de/de/job/wisse...

We are excited to introduce you to the #combineMARV project! 🦠

🔬 This #EUfunded project sets out to advance our understanding of virus cell entry, using the #MarburgVirus as a model – a critical cornerstone of #PandemicPreparedness.

Stay tuned for updates & visit our website 🔗 combine-marv.eu

Forscher starten große Untersuchung: Können Viren uns auch nützlich sein? Nicht nur Bakterien, auch zahllose Viren leben im menschlichen Körper. Wo genau sie vorkommen und was sie dort tun, das wollen Wissenschaftler jetzt ganz genau wissen.

Können #Viren nicht nur schaden, sondern auch nützen? Eine neue Studie kartiert die Billionen Viren, die unseren Körper besiedeln & eine große Rolle für unsere #Gesundheit spielen. So schützen einige mglw. sogar vor Hautkrebs. @tagesspiegel.de berichtet darüber. www.tagesspiegel.de/gesundheit/f...

A happy healthcare worker is showing a thumbs up sign.

A joyful person is holding up a poster.

Great news: #Tanzania 🇹🇿 has officially declared the end of the #Marburg virus disease outbreak.

Today, the Ministry of Health declared the end of the outbreak after 42 days with no new cases. This is a victory for public health in the country!

bit.ly/3XMKScU

Structural basis for Ebola virus nucleocapsid assembly and function regulated by VP24 - Nature Communications Here, the authors use cryo-electron microscopy to structurally characterise the Ebola virus nucleocapsid within virus-like particles, uncovering how specific interactions regulate viral genome synthes...

Structural basis for Ebola virus nucleocapsid assembly and function regulated by VP24

www.nature.com/articles/s41...

Second cluster reported in Uganda's Ebola Sudan outbreak

Second cluster reported in Uganda's Ebola Sudan outbreak www.cidrap.umn.edu/ebola/second...

Crimean-Congo hemorrhagic fever virus is transmitted by specific ticks. Present only south of 50’ latitude so far, global warming could make it move north. Within the German center for infection research (DZIF), @crnlsrhd.bsky.social at Marburg University develops vaccines against this virus.

Neues Hochsicherheitslabor: Mehr Forschung zur Vorbereitung auf Risiko-Viren - Pandemie Netzwerk Hessen An der Virologie der Universität Marburg entsteht ein neues Hochsicherheitslabor, ein BSL-4-Labor, um sich besser auf Pandemien vorzubereiten

In Deutschlands Hochsicherheitslaboren wird an hochpathogenen Viren wie dem Ebola Virus geforscht. In Marburg entsteht aktuell ein neuer Laborbau. Einen aktuellen Einblick in das Projekt geben @markuseickmann.bsky.social und @crnlsrhd.bsky.social:

pandemienetzwerk-hessen.de/neues-hochsi... (CR)

Thank you @gesvirologie.bsky.social for giving me the opportunity to present our data on the preclinical efficacy of an MVA-based vaccine approach against Marburg virus.
Proud to be part of this great collaboration with the Volz lab, TiHo Hannover.
#gfv2025 #dzif

Our DGI / DZIF Joint Meeting 2025 starts now 🚀

We are delighted to welcome everyone at the DGI-DZIF Joint Meeting in Munich! We look forward to insightful talks, poster sessions and engaging discussions.

Enjoy the conference #DGI_DZIF_AnnualMeeting

Ebola cases in Uganda rise to 9, while 265 others are being monitored under quarantine Health authorities in Uganda say Ebola cases in the country have risen to nine while 265 other people are being monitored under quarantine.

Ebola in Uganda
The number of confirmed cases rises to 9. 265 people are being monitored or under quarantine. So far the death toll remains at 1.
Vaccination efforts continue amidst significant vaccine hesitancy.
apnews.com/article/ugan...

NOIDs causative agents: week 6 (week ending 9 February 2025)

MERS-Fall in England entdeckt, Labor bestätigt.

www.gov.uk/government/p...

A Lancet Editorial: “American chaos: standing up for health and medicine”

“...to care is an act not of weakness, but of strength.”

The Lancet response: bit.ly/4jRb5Av

How good is the flu 💉 so far?
👇🏼Pretty darn good: overall, vaccine effectiveness is ~53-54% (higher in older adults). This means that the risk for acute respiratory illness is ⬇️ by HALF:

www.eurosurveillance.org/content/10.2...

📢 𝗝𝗼𝗶𝗻 𝗨𝘀 𝗮𝘁 𝘁𝗵𝗲 𝗗𝗭𝗜𝗙 & 𝗗𝗚𝗜 𝗝𝗼𝗶𝗻𝘁 𝗔𝗻𝗻𝘂𝗮𝗹 𝗠𝗲𝗲𝘁𝗶𝗻𝗴
We are excited to invite you to our Annual Meeting—explore the latest advancements in infection research!

📅 13-15 February 2025
📍 Holiday Inn Munich City Centre
🎤 Press Conference: February 13, 9:30 a.m.
🔗 More details: www.dzif.de/en/focus-inf...

#Ebola in Uganda: Confirmed cases up to 7, all contacts of the first confirmed case, the male nurse who died on 1/29. That is the only death so far. Other cases are family members or health workers who treated the nurse. Nearly 300 contacts have been identified & are being monitored. (source: #WHO)

Safety and immunogenicity of a bivalent Ebola virus and Sudan virus ChAdOx1 vectored vaccine in adults in the UK: an open-label, non-randomised, first-in-human, phase 1 clinical trial Our results suggest that the ChAdOx1 biEBOV vaccine was safe and well tolerated. Safety and tolerability data are consistent with other vaccines using the same vaccine backbone. A single 5 × 101⁰ vp d...

Safety and immunogenicity of a bivalent Ebola virus and Sudan virus ChAdOx1 vectored vaccine in adults in the UK: an open-label, non-randomised, first-in-human, phase 1 clinical trial www.thelancet.com/journals/lan...

Uganda Ebola Sudan outbreak total rises to 2, with more cases suspected

Uganda Ebola Sudan outbreak total rises to 2, with more cases suspected www.cidrap.umn.edu/ebola/uganda...

Marburg virus outbreak in Tanzania: MSF responds MSF is reinforcing case management capacities and implementing infection prevention and control measures in partnership with health authorities.

Marburg outbreaks need rapid detection, isolation, contact tracing, and infection control. With MSF, WHO, and the Tanzanian MoH involved, 2 deaths, 8 probable deaths, 64 suspected cases, and 281 contacts are being monitored to contain the spread.
🙏

www.doctorswithoutborders.org/latest/marbu...

Groundbreaking Ebola vaccination trial launches today in Uganda

In a global first, Uganda’s Ministry of Health, the World Health Organization (WHO) and other partners today launched a first-ever vaccine trial for Ebola from the Sudan species of the virus, and at an unprecedented speed for a randomized vaccine trial in an emergency.🧵

Near Real-Time Genomic Characterization of the 2025 Sudan Ebolavirus Outbreak in Uganda’s Index Case: Insights into Evolutionary Origins Introduction Case History: On January 30, 2025, the Ministry of Health declared an outbreak of Sudan Ebola Virus (SUDV) Disease in Kampala, Uganda, following the death of a healthcare worker at Mula...

First genome sequence from the Ugandan Ebolavirus outbreak with analysis: virological.org/t/990 and first filovirus genome submitted to Pathoplexus database: pathoplexus.org/seq/PP_0011C.... Great (and rapid) work from the National Health Laboratory, UVRI and partners.

Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane - Nature Communications Here, combining X-ray crystallography, cryo-electron tomography and animal studies, the authors show that the monoclonal antibody against Ebola virus glycoprotein (GP1,2) 3A6 exerts protection via bin...

Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane

www.nature.com/articles/s41...