Comic of the beetle from the cover of Massive Attack's "Mezzanine" meeting the crab from the cover of The Prodigy's "Fat of the Land".

Hi this joke is for me

Reminder: PhD position in my lab is open for two more weeks.
How do germ cells use their own private transcription factors? Come help us find out.
Fully funded. Deadline May 1.
Flyer attached — please boost! 🙏

Curiosity, cell clearance, and improv: A chat with Julia Batki In this interview, Julia Batki, FMI’s newest group leader, reflects on the early curiosity that drew her to science, why FMI is the right home for her lab, how studying cell clearance could help us un...

In this interview, @juliabatki.bsky.social, FMI’s newest group leader, reflects on the early curiosity that drew her to science, why FMI is the right home for her lab, how studying cell clearance could help us understand disease, and her love of improv.
www.fmi.ch/news-events/...

Exciting job offer: PhD Program Manager. Lead recruitment, support PhD candidates, and shape doctoral training at a top international life sciences campus. https://ow.ly/3YkN50YAuGM
Institute of Molecular Biotechnology, Max Perutz Labs Vienna, IMP, Gregor Mendel Institute of Molecular Plant Biology

How diverse is bacterial immunity ?

We report in @science.org how language models allowed us to predict 2.4M antiphage proteins spanning >23K novel potential systems.
👏 @emordret.bsky.social, @alexhv.bsky.social & al doi.org/10.1126/scie...

Explore them here defensefinder.mdmlab.fr/wiki/refseq_...

Every PI

Undaria pinnatifida gametophyte

Our work on chromatin evolution in brown algae is now published in @natecoevo.nature.com! We show that developmentally complex brown algae evolved without epigenetic silencing pathways long thought universal, underscoring why non-model lineages are important to study. www.nature.com/articles/s41...

Germ cells have their own versions of core transcription factors and fertility depends on them.
We're hiring a PhD student to figure out how! 📢
Fly genetics + proteomics + genomics. Fully funded.
Aarhus University 🇩🇰
Deadline May 1 👇

Please share with anyone who might be interested!

There is nowhere else in the world (that I am aware of) where phenology has been recorded as regularly as in Kyoto, Japan. Records here of peak cherry blossom bloom go back to the year 812. Those blooms have been getting earlier in recent years due to climate change and urban heat island effects.

Proper organelle regulation during mitosis is a must, but how do membrane-less condensates like PML bodies behave during cell division? In work led by Eric Aird, we found the balance of speckled proteins SP110 & SP100 to be the key. doi.org/10.1038/s415...

Hello, world! We are starting a worker cooperative to build, maintain, teach, and support open source scientific imaging software.

image.coop/blog/posts/2...

What an opportunity! Don’t miss it!!

Congratulations! Exciting times ahead 🧠🪱

I'm thrilled to announce that I'll be starting my lab as a SNSF starting grant professor at the Center for Integrative Genomics in Lausanne! I'm looking for PhD students who are fascinated about the neuronal basis of behaviour across species @fbm-unil.bsky.social

We’re excited to share our latest preprint on Fractal: our approach towards FAIR bioimage analysis at scale with OME-Zarr-native workflows.

Fractal defines interoperable tasks on OME-Zarr and provides a platform for TB-scale image analysis.

(1 / 10🧵)

www.biorxiv.org/content/10.6...

A consortium of group leaders from IMP, IMBA (Vienna BioCenter) and ISTA has been awarded an FWF Emerging Fields grant to study how germ cells safeguard and pass on genetic information across generations.

MycoMobilome: a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom Abstract. Transposable elements (TEs) are found in nearly all eukaryotic genomes. Despite significant advances in the sequencing of genomes, TE resources r

Need to annotate transposons in fungal genomes? 🧬
Good news #MycoMobilome is now live! Check it out here: doi.org/10.1093/narg...
Access the sequences through our Zenodo community (you can also contribute seqs with credit), and synchronisation with @dfam.bsky.social!

w/ @danielcroll.bsky.social

With Eugene Koonin, we propose a concept of “the selfish ribosome”, under which evolution of life is viewed as a ribosomal takeover, where the ribosome evolved to consume most of the cell’s resources, while other cellular componentry ensures the propagation of the ribosome. arxiv.org/abs/2602.23268

Our Lab is searching a postdoc for an exciting ERC-funded project that will start this summer. Apply if you’re passionate about multi-omics, cutting-edge computational approaches, and exploring biological questions across the animal 🪼 🪱 🐞 🦎 🦋 🕷️ tree of life www.biozentrum.unibas.ch/open-positio...

LINE-L1, HIV, Ty3 retrotransposons in insects.
several of these genomes are > 40% adenosine!

What is the molecular origin & evolutionary pressure resulting in A-rich genomes of retrotransposons & some retroviruses?

it must be so hardwired that hosts exploit this bias for genome defense

any ideas?

The political effects of X’s feed algorithm - Nature Among users initially on a chronological feed, 7 weeks of exposure to X’s algorithmic feed in 2023 shifted political attitudes and account-following behaviour in a more conservative direction compared...

Brainwashing, 2026 edition. This paper shows how X's algorithmic feed shifts people's views rightwards. It's a sophisticated, highly effective form of reorientation. And it is utterly chilling.
If you're still on that platform, unhook yourself now.
www.nature.com/articles/s41...

The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2 Weiss et al. structurally and functionally characterize the interplay between the human BAF chromatin remodeler and nucleosome-bound pioneer transcription factors, uncovering a highly dynamic remodeling process in which nucleosome-bound transcription factors bias the direction of BAF remodeling to regulate genome access.

The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2

The spring call for the ELBE Postdoctoral Fellows Program is open now: www.csbdresden.de/join-us/as-a.... Join the @csbdresden.bsky.social for a fully funded fellowship. @mpi-cbg.de @mpipks.bsky.social

Started this project years ago, but now everything is deposited on @addgene.bsky.social and a short @protocolsio.bsky.social is online. Try it out to make your own (cheap) homemade nuclease/Benzonase!

dx.doi.org/10.17504/protocols.io.261ged7xov47/v2

Thank you @jcoker10.bsky.social and Michael Lim!

How does the piRNA pathway solve the self vs. non-self problem? 🧬

Since piRNAs come from single-stranded RNA, how does the cell choose the right ones? For years, "piRNA clusters" were seen as THE privileged source. But are they really special and earmarked for biogenesis? (1/19)

A small polymerase ribozyme that can synthesize itself and its complementary strand The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

Ooooh. Cool new paper on origins of life. A simple 45-nucleotide RNA molecule that can perfectly copy itself.

www.science.org/doi/10.1126/...

🚀 We’re hiring! The Structural Biology Platform is seeking a Project Leader to advance cryo-electron tomography and expand capabilities at the FMI. Join a vibrant research community at the interface of structural biology, cell biology & disease mechanisms. Apply at: www.fmi.ch/education-ca...

Ulrich’s research will help advance our understanding of RNA biology & gene regulation, as well as how these mechanisms might be altered during viral infections & other diseases.
@hohmannulrich.bsky.social comes from the @impvienna.bsky.social / @imbavienna.bsky.social

www.imb.de/about-imb/ne...

Fun fuels collaboration Coordination and collaboration between biological systems is shaped over time by environmental pressures. Collaborations between scientists also evolve and grow in directions that would have been hard to predict from their outset. Sara Miller spoke with Felicia Basilicata and Claudia Keller Valsecchi about their long-term collaboration. The two started working together as postdocs and started their independent groups in Mainz, Germany and are now navigating continued collaboration after relocating to institutions in different cities.

Fun fuels collaboration