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Posts by Christine Sedore

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Out in print in Geroscience by @rosealsaadi.bsky.social: Pro‑longevity compounds extend Caenorhabditis elegans male lifespan and reproductive healthspan. Most interventions that help hermaphrodites also improve male lifespan, not necessarily reproductive heathspan. link.springer.com/epdf/10.1007...

2 months ago 10 7 0 0
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Make males live more than 400% longer and prevent sexual disfunction late in life?! We're down with it. Our latest preprint: Disruption of the insulin signaling pathway in C. elegans dramatically increases male longevity and enhances reproductive health late in life. www.biorxiv.org/content/10.1...

5 months ago 40 15 3 4
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#worm25 making sure we get our steps in

9 months ago 9 0 0 0
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NIA Caenorhabditis Intervention Testing Program: identification of robust and reproducible pharmacological interventions that promote longevity across experimentally accessible, genetically diverse po... A core facet of the National Institute on Aging’s mission is to identify pharmacological interventions that can promote human healthy aging and long life. As part of the comprehensive effort toward th...

Big overview of more than a decade of hard work: NIA Caenorhabditis Intervention Testing Program: identification of robust and reproducible pharmacological interventions that promote longevity across experimentally accessible, genetically diverse populations
link.springer.com/article/10.1...

1 year ago 9 4 0 0
Graph showing that the broccoli derivative sulforaphane makes the transcriptome of treated individuals look "younger" than untreated controls.

Graph showing that the broccoli derivative sulforaphane makes the transcriptome of treated individuals look "younger" than untreated controls.

New preprint. This is a fun one. Eat your broccoli, but not too much! The broccoli derivative sulforaphane extends lifespan by slowing the transcriptional aging clock www.biorxiv.org/content/10.1...

11 months ago 12 2 0 2
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Go worms! #worm25

9 months ago 85 21 0 4