More coverage of research on mini pill and asthma attacks in today's Times (£): www.thetimes.com/uk/healthcar... @chloebloom.bsky.social @imperialcollegeldn.bsky.social @imperialnhli.bsky.social @asthmaandlung.org.uk
Full paper by @chloebloom.bsky.social & colleagues is free to read in ERJ Open Research publications.ersnet.org/content/erjo...
Congratulations Nick!
Association of Dose of Inhaled Corticosteroids and Frequency of Adverse Events
Inhaled steroids prevent death in asthma. But higher doses can cause side effects, including cardiovascular disease
@chloebloom.bsky.social
@imperialnhli.bsky.social
#medsky
🔓Open Access
🔗 tinyurl.com/38fv8r2z
Diabetes treatments may reduce asthma attacks by up to 70% - Metformin reduced attacks by a third and GLP1 drugs (e.g. Ozempic) added a further 40% reduction 🫁
“It helped all asthma patients, regardless of how bad their diabetes was" - Dr @chloebloom.bsky.social
www.imperial.ac.uk/news/259036/...
Recent paper (Nature)-why are males more vulnerable to severe infections (ex acute #COVID), while females suffer more from autoimmunity (SLE, MS etc and also #LongCovid)? X/Y or hormones? We study adaptation of immune systems in gender-affirming testosterone treatment: nature.com/articles/s41...
Antidiabetic Medication and #Asthma Attacks: Clinical Practice Research Datalink (CPRD) cohort: #metformin was associated with a lower rate of #asthma attacks, with further reductions with the use of #GLP-1RA. jamanetwork.com/journals/jam...
Author interview: edhub.ama-assn.org/jn-learning/...
Thanks for your interest! I think the former as effect was independent of glycaemic control.
Please add me too Nick 👍
We found in 2 studies (cohort & self-controlled case series) that metformin (cheap, available, oral) associated with c.30% lower asthma attacks. Adding GLP-1 had 40% further effect. This was NOT from better glycaemic control/weight loss. Seen in T2 low & high asthma.
jamanetwork.com/journals/jam...