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Posts by Nick DeVito

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Nine outstanding journalists were honored with the AACR June L. Biedler Prize for Cancer Journalism during the Opening Ceremony at #AACR26. Learn more about their prize-winning stories: www.aacr.org/about-the-aa...

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It should be approved immediately, and probably should have already been available on compassionate use.

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Revolution Medicines touts ‘unprecedented’ data for pancreatic cancer pill In a trial, metastatic pancreatic cancer patients on the medicine lived twice as long as those on chemotherapy.

In a trial, metastatic pancreatic cancer patients on the medicine lived twice as long as those on chemotherapy. www.statnews.com/2026/04/13/r...

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Yvonne Awards 2026 The Yvonne Awards, symbolizing the strength and longevity of the yew tree, honors exceptional achievements in oncology with its unique Y-shaped sculpture that

5 𝐃𝐀𝐘𝐒 𝐋𝐄𝐅𝐓 ⏲️

Nominations for the 𝐘𝐯𝐨𝐧𝐧𝐞 𝐀𝐰𝐚𝐫𝐝𝐬 2026 officially close on 𝐀𝐩𝐫𝐢𝐥 1, 2026.

More details🔗https://bit.ly/4dfzRtl
Nominate now bit.ly/4uUMBfh

#YvonneAwards2026 #OncoDaily #GlobalOncology #CancerLeadership #Innovation #PatientCare #ASCO2026

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As we self-destruct, China moves ahead.

Fewer grants were awarded this year. A recent survey of #NIH funded scientists revealed that they had to close their labs, reduce work.

Fewer grants = fewer grad students = slow innovation

This is on Jay Bhattacharya et al.
🧪 www.nature.com/articles/d41...

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The DeVito Lab | Gastrointestinal Cancer Immunotherapy Our laboratory and clinical research program is focused on understanding the mechanisms that colorectal cancer and other gastrointestinal cancers use to evade the immune system during metastasis, or s...

My lab at Duke is dedicated to understanding immune evasion during metastasis in colorectal cancer and the development of biomarker-selected immunotherapies. Learn more at our website here!

www.thedevitolab.org

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Had to keep that admit chief complaint nonspecific, we’ll just go w run of the mill neutropenic fever

Yes I often say cardiologists have chest pain, pulmonologists have cough, and we have the internet. I’ve heard some strange stuff but I really dont get the desire/rationale for a rectal espresso.

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A young dad's colon cancer spread to his lungs with no warning. He says a clinical trial led to a miracle. Spencer Laird was diagnosed with colon cancer at 26. At 30, he was told it had returned and spread to his lungs, with one tumor the size of a golf ball.

Our first-line immunotherapy-only trial in Stage IV MSS CRC (BBOpCo) is pushing boundaries, changing lives, and is only the beginning. It is a foot in the door for an IO resistant disease, paving the way for novel biomarkers/combinations.

Read Spencer’s story here: www.cbsnews.com/news/colon-c...

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Yes. Please don’t do a coffee enema. Especially while neutropenic from chemo 😳

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Crush CRC is about to start!!! What a turnout on a beautiful day!

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A tomahawk missile costs the taxpayers the same amount of money as one five-year major NIH research grant. Remember that every time they tell us one of those missed the target, blew up paintings of enemy aircraft or tanks, or was the fifth and unnecessary hit on the same target.

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There is still time to join the 5K next week!

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Its March and that means colorectal cancer awareness month #crc

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He makes a great case against her nomination thanks for sharing, I will share!

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I was surgeon general — Trump’s nominee is not fit for my old job Leadership in the Public Health Service must remain merit-based and above politics.

Including my former colleague Rich Carmona.

thehill.com/opinion/heal...

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We won’t stand for it.

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Faces of Research | Duke Today

My incredible patient, a young mother who has overcome a stage IV, MSS CRC diagnosis is featured on Duke's Faces of Research.

She has only been treated on clinical trials, exhibiting a complete response to immunotherapy in the second line setting.

today.duke.edu/2026/02/face...

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Another life lost too young to colorectal cancer, RIP James Van Der Beek. The time for better prevention, screening, and treatment is now. #CureCRC

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“I am shocked and appalled,” one NCI scientist said. “We are moving funds away from so much promising research in order to do a preclinical study based on nonscientific ideas. It’s absurd.”

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2026 CRUSH Colorectal Cancer 5k Welcome to My Personal Page

The CRUSH CRC 5K is just over a month away!

join our team here:

www.supportdukehealth.org/site/TR/Colo...

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l-Fucose: a dietary sugar with multifaceted potential in the biology and therapy of cancer - Nature Reviews Cancer The conjugation of glycoproteins and glycolipids with the dietary sugar L-fucose is known as fucosylation. In this Progress article, Bitaraf et al. describe the latest work showing how fucosylation is deregulated in cancer, influencing tumour progression and therapeutic responses, and how it might be leveraged to treat cancer.

🚨 #REVIEW #PROGRESS 🚨

Fucosylation—the attachment of the dietary sugar L‑fucose to glycoproteins & glycolipids—is frequently altered in cancer. Bitaraf et al. outline its role in tumour progression and therapeutic response.

📖 👇

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A Call to Consider Patients' Medication List When Prescribing Cancer Immunotherapy Dozens of drugs can alter the immune system and affect activity of immune checkpoint inhibitors

Thanks to @medpagetoday.com for interviewing me about our recent @jco-asco.bsky.social commentary on how medications can influence immunotherapy!

www.medpagetoday.com/hematologyon...

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Over-the-Counter Medications May Alter Cancer Immunotherapy Outcomes DURHAM, N.C. – Immunotherapy is offering new hope for cancers that once had grim prognoses by harnessing the body’s own immune system to fight the disease, often sparing patients from the harsh side e...

I appreciate the write up from @dukemedschool.bsky.social on our recent @jco-asco.bsky.social commentary regarding how common medications can interact with immunotherapy!

corporate.dukehealth.org/news/over-co...

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“Of all the forms of inequality, injustice in health is the most shocking and inhumane because it often results in physical death" - Dr. MLK Jr.

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My mom ran the HIV prevention program for Hillsborough county (before it was shut down by Jeb Bush) which was one of my first volunteering experiences, inspiring me to pursue medicine. I witnessed so much pain, and many people are still suffering - the depth of this cruelty cannot be overstated.

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New @naturemedicine.bsky.social
The power of our mind to shape immune response, as seen in a randomized trial of trained neurofeedback for increased reward activity. More positive expectation-> more antibody response nature.com/articles/s41...
nature.com/articles/s41...

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PD-L2 Landscape and Correlation With Outcome: An Immunomic Analysis | JCO Oncology Advances PURPOSEPD-L1 and PD-L2 are inhibitory ligands that interact with PD-1 receptors, enabling immune escape. Although PD-L1 has been extensively studied, much less is known about PD-L2. PD-L2 expression c...

Anti-PD-1 > Anti-PD-L1, due to the existence of PD-L2. It may explain why PD-L1 is such a meh biomarker in many tumors, too.

ascopubs.org/doi/pdf/10.1...

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Addressing Common Medications That Influence Immunotherapy Response in Solid Tumors

Here is our publication in @jco-asco.bsky.social! We describe how common medications impact immunotherapy, how this affects practice and patients today, and outline ways to leverage this knowledge toward improved patient as well as our understanding of tumor immunology.

ascopubs.org/doi/10.1200/...

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For the first time, the five-year survival rate for all cancers has reached 70 percent, according to a new report, a trend that reflects the effectiveness of early prevention and detection strategies, and advancements in treatment and care, experts say. https://wapo.st/45T6Zm3

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***improved patient outcomes (need an edit feature!)

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