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Posts by Shane Gonen

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Assistant Professor in Structural Biology and Biochemistry, Department of Molecular Biology & Biochemistry University of California, Irvine is hiring. Apply now!

Our home department of Molecular Biology & Biochemistry at UC Irvine is looking to hire a new tenure-track assistant professor in the broad area of structural biology. Come be our colleague! recruit.ap.uci.edu/JPF09887

Please apply and/or share this post.

6 months ago 21 20 0 1

Herculean effort by the Wiles lab @UCIBioSci Congrats to the entire team and the first author postdoc Liz for this amazing cover art! Proud of #Nicholaslab members Naveena and Julio for the small role we played in this groundbreaking work

11 months ago 16 3 0 1

We’re thrilled to be featured on the May cover of Nature Microbiology... And our Research Briefing is out now—check it out, it’s 🔥! www.nature.com/articles/s41...

11 months ago 41 14 0 1
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"Phollow" the link to our May issue to read about...

💥lysing bacterial pathogens
⛽microbial alkane oxidation
🌱importance of seed-borne bacteria
🙅‍♀️protective antibodies for norovirus
🚰E. coli in urban drinking water

...and more!👇
www.nature.com/nmicrobiol/v...

11 months ago 25 5 1 3

Beautiful new work from our colleagues down the hall 🔬🥂

1 year ago 0 0 0 0

😳 good to hear you are ok!

1 year ago 0 0 0 0
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1 year ago 1 0 1 0

Thanks Steve :)

1 year ago 0 0 0 0
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Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I - Nature Communications Animal toxins can modulate action potentials and are important leads for therapeutics. Here, the authors use cryo-EM to show the interaction of the tarantula venom peptide Protoxin-I with a human volt...

Our #CryoEM study on the binding of a Tarantula toxin to a full-length human voltage-gated sodium channel has been published. Very proud of the awesome people in my lab 🥳🥂

www.nature.com/articles/s41...

1 year ago 45 7 1 1
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buckle up out there

1 year ago 1 0 0 0
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Molecular basis of proton sensing by G protein-coupled receptors Three proton-sensing G protein-coupled receptors (GPCRs)—GPR4, GPR65, and GPR68—respond to extracellular pH to regulate diverse physiology. How proton…

Groundbreaking work by @matthewkhoward.bsky.social and Nicholas Hoppe (not on bsky?) from the @willowcoyote.bsky.social @amanglik.bsky.social labs.

Mapping function to structure with deep mutational scanning to resolve the mechanisms of pH sensing GPCRs

www.sciencedirect.com/science/arti...

1 year ago 24 11 3 3

Ok, trying to bring my community back together... I created a starter pack for lipids and membrane protein aficionados!

Feel free to share, add and distribute, so we can come together again! 😍

go.bsky.app/AEeXh86

1 year ago 124 65 71 7
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I see 2 dolphins and a croc
image from not #cryoem

1 year ago 0 0 1 0

Happy Birthday Dequina!

1 year ago 1 0 1 0

Hello there :)

1 year ago 1 0 0 0

Hello :)

1 year ago 1 0 0 0

Hello there :)

1 year ago 0 0 0 0
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Maybe a heat shock protein. Like 1E94. Plenty of options though

1 year ago 1 0 1 0
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#cryoem grids don't have to be 3mm do they?

1 year ago 8 0 2 0

Here is a starter pack for CryoEM/ET enthousiasts
To be completed
go.bsky.app/JmQksC

1 year ago 110 76 72 6

Hello there :)

1 year ago 1 0 1 0