Histidine and tyrosine residues are targets for SIRT6 ADP-ribosylation activity Abstract. SIRT6, a highly conserved member of the sirtuin family, plays a critical role in diverse cellular processes, including gene regulation, DNA damag

Happy to share our latest article on SirT6 😊

In this paper, we demonstrate that SirT6 can efficiently ADP-ribosylate proteins on both histidine and tyrosine residues.

Check it out here:
royalsocietypublishing.org/rsob/article...