Abstract deadline approaching quickly (Nov 7, 2025) for the international #cancerneuroscience #symposium happening in Feb 2026!! Check out registration (SO CHEAP for 3 days!), abstract, and award details here:
mdanderson.cloud-cme.com/course/cours...
Come join us in pathology at @mdanderson.bsky.social ! A great opportunity with a fun and dynamic group! 🔬 #pathsky
October 1st, the start of one of my favorite months! One of my friends in IT made me this 3D printed brain 🧠 the spooky candies were a nice touch 🎃 #pathsky
Have also seen it stain pilomatrix-like carcinoma and some gliomas (one with a BRAF mutation).
Image of the Week!
Submitted by: Gabrielle Yeaney, M.D.
Directory Profile: www.pathologyoutlines.com/directory/ga...
Subspecialty: Neuropathology
Diagnosis: Normal pineal gland
#Pathology #PathologyOutlines #NeuroPath #PathSky
Dural-based mass with dural tail
Negative for SSTR2, no evidence of STAT6 fusion, and strong CD56 staining
GLI1 amplification present
🧠 take home point: GLI1-altered mesenchymal tumors can occur in the CNS and radiologically mimic meningioma!
academic.oup.com/jnen/advance...
#pathsky
MD Anderson research findings suggest that targeting interactions between some cells around the blood vessels could help make glioblastoma more vulnerable to treatment.
Read more: http://spr.ly/633204H8Uj #OncSky #EndCancer
📣TOMORROW, Friday, April 18, 12 noon CST!📣
Join the Brain Tumor Center of the Cancer Neuroscience Program seminar series! 🧠
We’re talking liquid biopsies in CNS tumors with @MDAnderson.bdky.social pathologist Dr. Leomar Ballester.
Login details: Email tpmarin@mdanderson.org
A photo of Dr Mi wearing a white coat on the big screen
Dr Mi shaking hands with the award giver
Two pathologists taking a photo in front of a plant
List of awardees and a flower
Superstar surgical pathology fellow Dr. William Mi was recognized with the Award for Clinical Excellence in Professionalism today! Congratulations to him for the well-deserved honor 🔬 #pathsky #medsky @mdanderson.bsky.social
MD Anderson and Texas Children’s Hospital announce a transformational collaboration dedicated solely to pediatric cancer care. This new first-of-its-kind joint venture, which will launch in early 2026, has a single mission: to end childhood cancer. #EndCancer
Yes they are!
In honor of upcoming Valentine’s Day here is a classic example of rosette-forming glioneuronal tumor. These grade 1 tumors typically show a hotspot mutation in FGFR1 along with PIK3R1 or PIK3CA alterations and are usually found in the fourth ventricle 🌹 ♥️ 🥀 🧠 🔬 #pathsky #neuropath #medsky
TFE3
#PathSky 43F with a solitary lung mass. Relatively circumscribed, nests and interesting micropapillae of lightly eosinophilic epithelioid cells. Negative for everything except TFE3. Dx?
This is a clear cell stromal tumor of the lung. They have YAP1::TFE3 fusions, which are also present in YAP1::TFE3-fused hemangioendotheliomas and some pulmonary PEComas. Abbas Agaimy described these. pubmed.ncbi.nlm.nih.gov/33899786/
Palpably unfair act is definitely entering the lexicon #eagles
Grateful to work with such a fantastic group to learn new things and help our patients the best we can! #pathsky #medsky
Smear preparation showing a fibrillary spindle cell neoplasm
Close up of the prior smear showing fibrillary to feathery cytoplasm and ovoid nuclei
H&E stained permanent section showing a whorled to spindled bland appearing tumor
Nuclear staining for TTF1
Just like Texas rarely sees snow ❄️, every once in a while you will find a primary tumor of the posterior pituitary so keep it in mind during frozen section analysis! Here is a classic example of pituicytoma showing diffuse nuclear positivity for TTF1 #pathsky #neuropath #medsky 🔬 🧠
MUC4.
#PathSky 32M with extra-axial, dural-based, frontoparietal mass. Clearly malignant epithelioid cells arranged in cords and nests in a sclerotic background. Looks a lot like a sclerosing epithelioid fibrosarcoma, and it is strongly MUC4-positive. So, we’re done, right?
Nice!
😂 thanks! The upside to living in Texas is you get a beautiful mild winter after a brutally hot summer
Although this comment prompted me to go down a rabbit (er lizard?) hole and I found this paper about an endolymphatic sac neoplasm in a gecko
meridian.allenpress.com/jhms/article...
The pathology case is human, the equine pictured is just for fun
H&E stained section of a papillary neoplasm with bland cells arising within the ear
Higher power view of a papillary neoplasm stained with H&E
A bay horse jumping an oxer in a grass field with a blue sky overhead
Jumping into 2025 with an endolymphatic sac tumor, a VHL-associated neoplasm arising in the posterior petrous bone of the ear #pathsky #eqbsky #neuropath #entpath
A bay horse and a person wearing a Buc-ee shirt with a blue sky in the background
An enormous steer
Aired our grievances yesterday for Festivus and now enjoying the magic of Christmas Eve 🎄🎁🦄 #eqbsky
A cytology preparation showing pink amorphous blobs
Same specimen after polarization highlighting the refractory nature of the material
Asteroid hyalosis is an aging-associated condition of the eye where calcium and phospholipids build up giving the eye a grossly “glittery star-like” appearance (hence the name). Here is a vitreous cytology specimen before and after polarization showing the material 💫 👁️ #pathsky #medsky
Ours just turned 3 but went through a phase claiming a giant was in her room and so we have taken to “shooing the giant” so maybe you can shoo monsters too 😂 kids are so creative and weird but alas the solutions are usually equally creative and weird
We need more back up coconuts in this world 😂 🥥
Smear preparation of a meningioma with chordoid features
Permanent section of a chordoid meningioma showing focal whorl formation
Smear preparation of a chordoma
Permanent section of a chordoid highlighting the cords of tumor cells in a myxoid background
Some tumor look-a-likes on this Friday:
Chordoid meningioma and chordoma can share similar features of cords of cells in a myxoid background. Chordoma shows diffuse nuclear Brachyury expression whereas chordoid meningioma is positive for SSTR2 helping to differentiate the two 🧠 #pathsky #neuropath
A grey and white bunny staring at the camera
A mischievous bunny chewing on a book
More bunny gnawing on a book
A bunny enjoying the holiday ambiance
Alternatively, if you are looking for something else consider mailchi.mp/houserabbits...
This is where we adopted our adorable bunny Teepah!