MAJOR UPDATE: I found the best free restaurant bread in the United States www.theatlantic.com/magazine/202...

I'm sad that, at least based on the Bluesky search box, this is the most recent RevMed post.

Hello people!! Today's news is a bfd!!

ir.revmed.com/news-release...

Could be Bezos's freshman roommate @hartwiggroup.bsky.social

Günther Maier in Tenerife in February 2007. From his LiC autobiography, Fig. 7.8.

Some of Günther Maier’s highlights from 60 years. From his LiC autobiography.

🌻Rest in peace, Günther Maier. The chemist who made one “impossible molecule” after another died on April 10 at the age of 94. He was a modest man who trained a large number of PhD students. His achievements were recognized with the Adolf von Baeyer Memorial Medal of the GDCh. l-i-c.org/1125

I’m a Nobel Prize-winning immigrant. I can no longer recognize this country. Attacks on science and immigrants are destroying America.

Wow
this says it all
PLEASE READ
newsletter.ofthebrave.org/p/im-a-nobel...

Pretty nice set of structure drawings at NYT here #chemsky

www.nytimes.com/interactive/...

A line grant of the cumulative numbers of awards for NSF from fiscal years 2021-2026. The curve for fiscal year 2026 lies below well the other curves.

NSF update

Still looking very bleak.

4/5

Direct CO2 Reduction to CO with an Fe4S4-Based Coordination Polymer Fe4S4 clusters play essential roles in nature, classically in electron transport but increasingly in newly discovered reactivity or catalysis. These roles have spurred interest in developing synthetic...

Excited to share the groups most recent cluster based work by first-author Linh Le, and collaboratively with @annawuttig.bsky.social and @gagliardilaura.bsky.social groups. Iron-sulfur clusters can serve as direct electrocatalysts for carbon dioxide reduction!

pubs.acs.org/doi/10.1021/...

I Am Here to Watch the Birthright-Citizenship Arguments, but Not in a Threatening Way Can’t a president go watch his justices?

oh no he’s got Mr Marbury www.theatlantic.com/newsletters/...

If you like harnessing carbenes from di-chlorides, you’ll LOVE skeletal editing with tri-chlorides!

Congrats to Bethany, Hojin, Victoria, and our collaborators from Chicago (Ethan & Mark Levin) and California (Anna, Zhang & Dave Olson)!

Open access: authors.elsevier.com/a/1mqdE8jWHE...

Skeletal editing by iron-catalyzed carbene insertion of trichloromethanes Direct interchange between five- and six-membered nitrogen heterocycles by skeletal editing is valuable in drug discovery. Specifically, inserting a c…

Back in 2019 I wrote my first grant, for the ACS PRF, in which I proposed carbon insertion into LSD (truly a pipe dream at the time). After teaming up with @nagiblab.bsky.social and @deolsonlab.bsky.social, the dream is finally a reality!

www.sciencedirect.com/science/arti...

A text image of a small part of the transcript of a conversation between Ari Shapiro and David Simon (Creater of 'The Wire') on a segment on NPR during the wirter's strike of 2023: Shapiro: OK, so you've spent your career creating television without AI, and I could imagine today you thinking, boy, I wish I had that tool to solve those thorny problems... Simon: What? Shapiro: ...Or saying... Simon: You imagine that? Shapiro: ...Boy, if that had existed, it would have screwed me over. Simon: I don't think AI can remotely challenge what writers do at a fundamentally creative level. Shapiro: But if you're trying to transition from scene five to scene six, and you're stuck with that transition, you could imagine plugging that portion of the script into AI and say, give. me 10 ideas for how to transition this. Simon: I'd rather put a gun in my mouth.

And if you think this is just some BS meme image, you can listen to the man himself: www.npr.org/transcripts/...

Resizing

Microsoft Word
a joke
I have

about
an image

Potassium tert-Butoxide: Solubility, Solution Structure, and Reactivity Fundamental properties including solubility and structure–reactivity correlations of potassium tert-butoxide (KOtBu) are described in this manuscript. A combination of donor solvent titration, diffusion NMR, and DFT studies established that KOtBu exists in one of three solution structures: (1) unsolvated cubic tetramer in non-Lewis basic solvents, (2) disolvated cubic tetramer in Lewis basic solvents, and (3) solvated monomer in protic solvents. These studies dispel the notion that strong aprotic donor solvents lead to deaggregation of KOtBu cubic tetramer. In DMSO, a concentration-dependent equilibrium mixture of bis-DMSO-solvated cubic tetramer, dimsylpotassium, and tert-butanol is formed. Donor solvent association with potassium was contextualized in terms of periodic trends within the alkali metal series. The previously reported 1:1 complex of KOtBu and tert-butanol was found to be highly insoluble and affords poor availability of KOtBu when employed in a model dehydrohalogenation reaction. Reactivity can be recovered by the inclusion of strongly Lewis basic donor solvents that disproportionately stabilize the transition state.

So you think you know KOtBu…
Well my colleagues in #PfizerChemistry process chem have done some amazing work to find out a lot more about a very useful base #ChemSky

Cross- and branched-selective hydroalkenylation by metal hydride selection Controlled placement of branch points along carbon chains is a core capability in the synthesis of materials, agrochemicals, and pharmaceuticals. Metal hydride hydrogen atom transfer (MHAT) to alkenes...

In @science.org for chemsky this week, @shenvi.bsky.social group report that lutidinium and manganese are the Goldilocks reagents to help nickel and cobalt cross-couple two different olefins

www.science.org/doi/10.1126/...

Nitrogen, Ammonia, and the Strait of Hormuz

For those who may have missed it over the weekend: chemistry, fertilizer, and the Iran War.

Michael Ziebel and Song Lin Join Stanford Chemistry | Chemistry The Department of Chemistry is pleased to announce the forthcoming addition of two esteemed chemists to our faculty this fall.

📢 Join us in welcoming @mikeziebel.bsky.social & @songlin1.bsky.social as they join our dept. and esteemed faculty in chemistry this fall. Their contributions will further advance our mission of academic excellence and research innovation!

chemistry.stanford.edu/news/michael...

#WelcometoStanford

I just renewed my membership in @aaup.org Their advocacy nationwide and the strong support of @ncaaup.bsky.social and @unc-ch-aaup.bsky.social on our campus has been a breath of fresh air in these challenging times

Now accepted @jacs.acspublications.org 🥳

pubs.acs.org/doi/full/10....

www.organic-chemistry.org/abstracts/li...
α-Chlorodiazirines as thermal precursors to the corresponding chlorocarbenes for a synthesis of 3-(hetero)arylpyridines and quinolines

We are pleased to share that Assistant Professor Anna Wuttig has been named a 2026 Sloan Research Fellow! 🏆

This honor from the Sloan Foundation recognizes early-career scientists with the potential to revolutionize their fields.

#UChicago #Chemistry #SloanFellow #Electrochemistry #WomenInSTEM

Heart-wrenching.

@merz.bsky.social I read the latest "AI is coming" manifesto by Shumer and was genuinely confused to read a prediction that was a ~year old that did not happen - and it is surprising to me that these folks don't recognize how damaging it is to their credibility

This is obvious bait but ok, let's hear it

At least one of those is... Definitely not a nitrile

Pro-LLM academics bemoaning how long it takes to write and review papers are telling on themselves. Those tasks are supposed to take a long time because that's how you can be thoughtful, thorough, and rigorous.

Filtering yourself is how you only communicate things you think are worth reading.

Publishers are already seeing unprecedented quantities of AI slop and unethical AI use by authors and reviewers, and it's terrifying that tools like this will open the floodgates further. Gen AI is a plague and I wish it a swift death.