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Dynamic metal coordination controls chemoselectivity in a radical halogenase - Nature Chemical Biology Radical FeII/α-ketoglutarate-dependent halogenases are powerful biocatalysts for C–H functionalization. Here, the authors reveal the mechanistic basis for chemoselectivity in a lysine halogenase.

Congratulations to former student Eli and the team on their new paper in Nature Chemical Biology! Here they show that the difference in radical rebound of FeII/aKG halogenases is uniquely controlled by the switching of the metal ligand bond axes! Take a look: www.nature.com/articles/s41...

5 months ago 8 3 0 2

#secmet #natprod tRNA deacylases as resistance markers to identify nonproteinogenic amino acid-producing biosynthetic gene clusters!

1 year ago 2 0 0 0
Video

There are now 24 step-by-step guides, explaining how to create these ⬇️ data visualizations with R/ggplot2 - I hope this is a useful resource. Find them all here: joachimgoedhart.github.io/DataViz-prot...

1 year ago 551 193 17 14

You get a really interesting phenotype if you mix the protein shake and tequila 🤔

1 year ago 0 0 0 0
A collection of 9 color palettes inspired by plants / anime.

A collection of 9 color palettes inspired by plants / anime.

A photo of bird of paradise, the hex code of the color palette inspired by it, and the color palette itself in normal and deuteranopia vision.

A photo of bird of paradise, the hex code of the color palette inspired by it, and the color palette itself in normal and deuteranopia vision.

Color palette "liam", inspired by love in a mist flower, in normal and deuteranopia vision.

Color palette "liam", inspired by love in a mist flower, in normal and deuteranopia vision.

Color palette "bir", inspired by blue iris flower, in normal and deuteranopia vision.

Color palette "bir", inspired by blue iris flower, in normal and deuteranopia vision.

3 new color palettes added to my GitHub repository of plant/anime inspired palette collections: bird of paradise (bop), love in a mist (liam), and blue iris (bir). Hex codes, how to use, and the respective inspirations are available at GitHub page: github.com/cxli233/Colo... #DataVisualization

1 year ago 23 2 0 0
Shake-flasks, used for growing bacteria, are lined up in a row. The colors of the bacterial cultures are light brown, dark brown, and yellow.

Shake-flasks, used for growing bacteria, are lined up in a row. The colors of the bacterial cultures are light brown, dark brown, and yellow.

The same actinobacteria, different growth media! More than the colors, what shocked me was the smell. The far right flask smelled like pineapples 🍍 while the others were all earthy, particularly the third from the left. #secmet

1 year ago 7 0 1 0
Agave americana in bloom. Porto Covo, Portugal

Three tall succulent-style plants that grow close to the ground suddenly erupted into giant towers of brush-like flowers arranged around a central stalk.  It looks like a spindly pine tree, if you squint at it.

Agave americana in bloom. Porto Covo, Portugal Three tall succulent-style plants that grow close to the ground suddenly erupted into giant towers of brush-like flowers arranged around a central stalk. It looks like a spindly pine tree, if you squint at it.

The Maguey cactus (Agave americana) is also known as the "Century Plant" because it blossoms only once during its 10 - 30 year life, then dies... but what a blossom: up to 10 m/32 ft high

There's lots to talk about, but my favorite fact: it's in the same family as asparagus.

(📷: Alvesgaspar)

1 year ago 244 41 11 2
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CoE: received
Visa application: submitted
Pants: at the tailor
It's a good day

1 year ago 0 0 0 0

I'm getting antsy. I've been out of the lab for months and I can't apply for my visa yet 😭 would love to start the next chapter of my career and get out of limbo... also I'm running out of money 😀

1 year ago 1 0 0 0