Finally, as always, my focal point on Thursday at #HRS25 will be the @CardiacEPS session from 11 am to 7 pm, room 33A-C. YIA poster session and amazing lectures, including Moe lecturer Dr. Dan Roden. Boxed lunches and cocktail hour for members. Be there! cardiaceps.org/s/CES-progra... #HRS25 #EPeeps

Last but not least, the symposium will close from 2:15-3:15 pm with "Civil Unrest: Heterocellular Interactions In Cardiac Arrhythmogenesis". Hopefully our chairs Drs. Clancy and Kohl can keep the melee relatively collegial. eppro01.ativ.me/web/index.ph... #HRS25 #EPeeps

Then, sticking in the same room from 11:45 am to 12:45 pm, we have "Neighborly Relations: Intercellular Communication And Electrical Propagation". This will include our "headliner" Dr. Ed Lakatta delivering the Zipes lecture! eppro01.ativ.me/web/index.ph... #HRS25 #EPeeps

Friday at #HRS25 will be dominated for me by the Basic/Translational Science Symposium!! From 10-11 am in Room 6A, we have "Welcome to the Neighborhood: Diversity of Heterocellular Interactions in the Heart" eppro01.ativ.me/web/index.ph... #HRS25 #EPeeps

... this will be followed by an invigorating Panel Discussion led by Dr. Ken Bilchick, presented as a roundtable session from 12:45 to 1:45 pm in the Exhibit Hall. Science on the main stage! eppro01.ativ.me/web/index.ph... #HRS25 #EPeeps

I'm also super excited to attend a pair of sessions on Saturday focusing on the creation of the New HRS Research Network. First, we will have a series of talks from 9:45 to 10:45 am in Room 29A – this one really has a blockbuster cast! eppro01.ativ.me/web/index.ph... #HRS25 #EPeeps

First up, I'll be giving a talk (yay!) in a session on Friday at 10 am in Room 30A-E: "Innovating Cardiac Ablation: Integrative AI Approaches for Personalized Arrhythmia Management". Please come say hi! eppro01.ativ.me/web/index.ph... #HRS25 #EPeeps

Time for a rundown of some of the amazing basic/translational science sessions that will be taking place at @heartrhythmsociety.bsky.social's #HRS25 meeting next week in San Diego! #HRS25 #EPeeps

3/ Explainability is critical in medical AI. Tools like deliver great performance but also empower clinicians to verify and refine results, building trust in AI systems. A big step toward reducing arrhythmia-related adverse events and supporting sustainable ECG data analysis.

2/ Brought to you by Fleury et al. (senior author: Dr. Maison-Blanche). Game-changer for managing long-term ECG recordings!

🔑 Highlights:
• F1 scores: 99% for arrhythmia detection, 95% for AF, 90% for atrial flutter.
• Modular design enables explainability and manual adjustment of AI outputs.

A deep learning modular ECG approach for cardiologist assisted adjudication of atrial fibrillation and atrial flutter episodes Detection of atrial tachyarrhythmias (ATA) on long-term electrocardiogram (ECG) recordings is a prerequisite to reduce ATA-related adverse events. However, the burden of editing massive ECG data is not sustainable. Deep learning (DL) algorithms provide improved performances on resting ECG databases. However, results on long-term Holter recordings are scarce.

1/ 🧠❤️🤖 New in @heartrhythmsociety.bsky.social's #HRO2 journal: a deep learning modular ECG approach for cardiologist-assisted adjudication of AF and atrial flutter. www.heartrhythmopen.com/article/S266... #ExplainableAI #DeepLearning #AFibCare #BiomedicalAI #EPeeps

Providing medical care in health resource–constrained global areas: Syria

3/ Takeaway from Dr. Uma Srivatsa's editorial:
“Prevention is key to addressing AF risk factors & reducing strain on underfunded systems.” www.sciencedirect.com/science/arti... #Cardiology #AFibCare #EPeeps

2/ 🔑 Key points:
• 43% of patients readmitted within 30 days.
• Cardiac issues were the primary driver.

Thirty-day unplanned readmissions following hospitalization for atrial fibrillation in a tertiary Syrian center: A real-world observational cohort study Atrial fibrillation (AF) is the most common arrhythmia worldwide. Data regarding 30-day readmission following index admission for AF in the developing…

1/ 🌍 Insightful new study in @HRS_O2Journal: Dr. Antoun et al. (senior author: Dr. Zakkar), explore 30-day readmissions after AF hospitalization in Syria. A critical step toward understanding AF care in resource-limited settings. www.sciencedirect.com/science/arti...

Special thanks to collaborators Pranav Bhagirath, Marina Strocchi, Martin Bishop, & Gernot Plank for their contributions to this work! We hope you enjoy the review and look forward to your thoughts. 🙌

To advance the discussion, we propose a framework for more precise and granular descriptions of “Digital Twins” in biomedicine. Clear definitions will help ensure productive and responsible progress in this exciting field.

As we caution in the review, “To ensure this growth proceeds responsibly, we believe caution must be exercised to avoid cavalier use of the digital twin vernacular by biomedical researchers.

Digital Twins in cardiovascular medicine hold incredible promise, but realizing their potential is a long journey. Many foundational elements as articulated by pioneers of this field like Dr. Michael Grieves—like continuous real-virtual data exchange—remain aspirational in computational physiology.

From bits to bedside: entering the age of digital twins in cardiac electrophysiology Abstract. This State of the Future Review describes and discusses the potential transformative power of digital twins in cardiac electrophysiology. In this

Thrilled to share our new “State-of-the-future” review in #ESC Europace: “From bits to bedside: entering the age of digital twins in cardiac electrophysiology” (with apologies to Drs. Zipes, Jalife, & Stevenson!). #EPeeps Link: academic.oup.com/europace/art...

🎉 The HEARTS Act has passed the Senate & heads to President Biden's desk! HRS, a proud Smart Heart Sports Coalition member, led a grassroots effort urging legislators to act. Soon, schools nationwide will have AEDs, CPR training, & emergency plans—lifesaving tools for every kid ❤️smartheartsports.com

Proud to share new work from our Cardiac EP collabs at @uwmedicine.bsky.social! Honoured to be involved in this work to better understand arrhythmia mechanisms in #rToF. Congrats to lead and senior authors Dr. Johnson and Dr. Nazer! #EPeeps @uwbioe.bsky.social authors.elsevier.com/c/1kAn75VtUy...

Quantitative validation is needed, but this is truly interesting stuff! Congrats to the whole team! Read more great science at @heartrhythmsociety.bsky.social's #HRo2 journal!!

Many interesting findings here, but perhaps the most compelling – in patients who experienced a flutter recurrence following CTI ablation, T2-weighted CMR had a distinctly weaker pattern of hyper enhancement based on visual assessment.

The study describes "Local atrial bipolar EGM voltage drops during CMR guided catheter ablation of typical Afl: Associations with delivered radiofrequency energy and peri-procedural imaging"

Local atrial bipolar electrogram voltage drops during cardiac magnetic resonance guided catheter ablation of typical atrial flutter: Associations with delivered radiofrequency energy and peri-procedur... Cardiac magnetic resonance (CMR)-guided catheter ablation of the cavotricuspid isthmus (CTI) has been proven feasible, but determinants of local electrogram (EGM) voltage drops during radiofrequency (...

In the current (November) issue of @heartrhythmsociety.bsky.social's #HRo2 journal, we have a fascinating study by Nies et al. #EPeeps www.heartrhythmopen.com/article/S266...

For any #EPeeps who have made the transition to @bsky.app, please drop a follow for @heartrhythmsociety.bsky.social and help us establish a user base on this new platform!

go.bsky.app/MmucfgJ

Let me know who else should be added!

Figure showing Kaplan-Meier curves of the primary outcome.

#AHA24 attendees, check out these key findings from today's JAMA Cardiology presentations 🫀

Partial cardiac denervation effectively reduced the occurrence of postoperative atrial fibrillation after isolated CABG without additional postoperative complications. ➡️ ja.ma/3Z93Iw2

Amazing session at #AHA24, with many provocative questions about paving the way towards even closer collaborations between bioengineers, basic scientists, and healthcare professionals. Explainable AI and computational physiology are powerful tools for 21st century cardiology -- from bits to bedside!

At #AHA24, Dr. Nanette Wenger reminds us we’re all ‘standing on the shoulders of giants’ in healthcare. As we celebrate 100 years of Scientific Sessions, we honor the pioneers who paved the way and look ahead to a new century of innovation.