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Posts by Steve Persaud, MD, PhD

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Streptavidin-drug conjugates streamline optimization of antibody-based hematopoietic stem cell transplant conditioning Key PointsCD45-ADCs with various payloads were compared using a modular SAv-drug conjugate platform, which enabled rapid, efficient ADC screening.The PBD d

This article, recently published in Blood ICT, was accepted through our second look rapid response program. Check it out and consider giving your own research a second chance: ashpublications.org/bloodict/art...

2 months ago 2 1 0 0

Glad to have had the opportunity to contribute to this commentary describing this important work from Seung Kim’s lab

3 months ago 1 0 0 0
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Streptavidin-drug conjugates streamline optimization of antibody-based hematopoietic stem cell transplant conditioning Hematopoietic stem cell transplantation (HSCT) conditioning using antibody-drug conjugates (ADCs) is a promising approach to preparing patients for tr…

Proud to post the final version of the Persaud Squad's first manuscript-we made a panel of SAv-drug conjugates enabling in-house, cost-effective ADC production from any biotinylated mAb. We compared CD45-ADCs with different payloads as HSCT conditioning agents.

www.sciencedirect.com/science/arti...

5 months ago 2 0 0 0
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After all the damage that tornado caused, seeing this pop of color growing along my walkway is an especially welcome sight

10 months ago 1 0 0 0
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Well that sucks.

Living mostly unscathed by St Louis weather for almost 19 years, I guess I was due (and by the looks of it, pretty damn lucky it wasn’t worse). Hoping everyone else in the area is doing alright.

11 months ago 1 0 0 0

Tennis player gets caught ripping on her opponent, laments being known hereafter on social media as "Harriet Fart"

1 year ago 0 0 0 0
Mike Visits Nacho's Family Auto Shop | Cobbler | Better Call Saul
Mike Visits Nacho's Family Auto Shop | Cobbler | Better Call Saul YouTube video by Breaking Bad & Better Call Saul

Preparing a colleague for trying to explain anything single-cell/omics to me:
www.youtube.com/watch?v=Mm5a...

1 year ago 0 0 0 0
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DKMS Awards Night in Florence Celebrating Scientific Excellence

Honored to receive a John Hansen Research Grant from @dkms-de.bsky.social to support my research program in minimally toxic stem cell transplant conditioning @washumedicine.bsky.social .

professional.dkms.org/news-events/...

1 year ago 2 0 0 0
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Paas got a little weird with their Easter dye kits this year

1 year ago 1 0 0 0

“My talk may go a few minutes over time.”
bsky.app/profile/cnn....

1 year ago 0 0 0 0
Measles outbreak spreads as experts warn of lasting immune effects
Measles outbreak spreads as experts warn of lasting immune effects YouTube video by CBS Mornings

On being asked if Vitamin A or cod liver oil helps with measles, Dr. Celine Gounder’s face at 3:50 is all of us:
m.youtube.com/watch?v=PSwP...

1 year ago 1 0 0 0
Steve Ballmer Runs Around Like A Maniac On Stage (Motivational Presentation)
Steve Ballmer Runs Around Like A Maniac On Stage (Motivational Presentation) YouTube video by Tom Corson-Knowles

Barack Obama gets standing ovation at Clippers game while seated next to Steve Ballmer, who’s probably thinking the entire time “you call that a welcome?”
m.youtube.com/watch?v=_WW2...

1 year ago 0 0 0 0
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Damn straight, Southwest inflight app. As it should be.

1 year ago 1 0 0 0
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Ugh…a truly brutal homecoming awaits our return from Honolulu.

1 year ago 0 0 0 0
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Playing conference hooky. Worth it. #Tandem25 #DontTellJohn

1 year ago 2 0 0 0
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ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation ArfGAP2 is a dual regulator of STING signaling and proton efflux in specific cell types, with STING proton channel activity regulating Golgi transit and secretion of cytokines. Autoinflammatory diseas...

A well-deserved shout out to my old friend Subhajit and his coauthors in the Miner lab @pennrheum.bsky.social on their new paper in @cp-cell.bsky.social . You love to see it!

www.cell.com/cell/abstrac...

1 year ago 2 0 0 0
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All aboard the impulse buy express. My pre-conference supply run looks an awful lot like I'm studying for a midterm #Tandem25

1 year ago 3 0 0 0
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Quart-size bag to get through TSA: check. #Tandem25

1 year ago 0 0 0 0

With all this uncertainty on the federal funding scene, it’s especially sweet starting the day with news of a 3 year foundation grant win. More on the new award very soon!

1 year ago 1 0 1 0
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Good News - email phishers don't seem to be trying anymore

1 year ago 0 0 0 0
American Society of Hematology Announces 2025 Scholar Award Recipients - Hematology.org American Society of Hematology Announces 2025 Scholar Award Recipients

A well-deserved congratulations all around to the 2025 @ash.hematology.org Scholar Award recipients. Particularly proud to see WashU bring home 3 this year! www.hematology.org/newsroom/pre...

1 year ago 1 0 0 0

A weird and unfortunate coincidence that two of my favorite CD numbers (45 and 47) are also, as of today, the numbers of my least favorite president. What’s next, a return to politics by former senator Christopher “Kit” Bond (“c kit”)?

1 year ago 1 0 1 0
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Lift as You Climb: An Interview With Michael R. DeBaun, MD, MPH | ASH Clinical News | American Society of Hematology

Great read shared with me by my labmate Dilan. Sound advice for all of us who want to promote “a rising tide that lifts all boats” in academia through mentorship. The 10 rules of the laboratory definitely needs to be a fridge magnet ashpublications.org/ashclinicaln...

1 year ago 2 2 0 0
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My neighborhood theater gets it. Lethal Weapon: Christmas movie.

1 year ago 1 0 0 0
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An interesting keychain we got as a free gift with a purchase - any ideas as to what this red thing is (wrong answers welcome)?

1 year ago 2 0 0 0
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#ASH24 ... it begins. There's gotta be an AI or other algorithm that sees "pathologist" in my member metadata and excludes me from the drug ad flood

1 year ago 3 0 0 0
Congratulations to our Honorific and Funded Award Winners Meet the recipients of our honorific and funded ASGCT awards.

Proud to receive a fellowship from @asgct.bsky.social to embark on a brand new project to develop a novel cellular approach to conditioning for hematopoietic stem cell transplants without chemotherapy or irradiation! www.asgct.org/publications...

1 year ago 7 1 0 0
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Off to #ASH24 soon, and once again finding creative ways to blow through leftover pasta sauce before taking off for 5 days

1 year ago 4 0 0 0
Paper: Anti-CD117 Plus Anti-Sirpα or Fc-Silenced Anti-CD47 Enables Hematopoietic Stem Cell Depletion and Syngeneic Engraftment without Development of Severe Anemia

An #ASHHaiku about some new preclinical work in the DiPersio lab, coming soon to an ASH near you:

Anti-kit and SIRP
Transplant sans chemo or rads
Stop by to learn more

ash.confex.com/ash/2024/web...

#ASH24 #bmtsm

1 year ago 3 0 1 0
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Ducks Changing Their Minds
Ducks Changing Their Minds YouTube video by Sobel Promotions

No lunch at non-mandatory med student noon seminar

(I held off the lame science memes as long as I could...)

www.youtube.com/watch?v=ygSX...

1 year ago 2 0 0 0