mTME and CRD Approaches for ta-IPAA in UC Have Equivalent Safety Profiles Modified total mesorectal excision and close rectal dissection demonstrate comparable short-term safety profiles in UC with transanal IPAA.

Modified total mesorectal excision and close rectal dissection yield similar short-term complication rates, indicating that both techniques are safe for transanal #IPAA.
www.gastroenterologyadvisor.com/news/mtme-and-crd-approa...

The ELF Test May Be Most Accurate NIT in MASLD With Cardiometabolic Comorbidities Hypertension in men and an increasing number of cardiometabolic criteria were associated with higher risk for advanced fibrosis and at-risk MASH.

Higher cardiometabolic burden is linked to fibrosis risk in #MASLD; the ELF test outperforms other noninvasive tools in detecting advanced #liverfibrosis.
www.gastroenterologyadvisor.com/news/the-elf-test-may-be...

Virtual Multidisciplinary GI Care Improves Outcomes, Reduces Costs Virtual multidisciplinary GI care significantly improves patient engagement, symptom control, quality of life, while reducing health care use and costs.

Multidisciplinary GI care is associated with better clinical outcomes and high patient engagement. #gastroenterology
www.gastroenterologyadvisor.com/news/virtual-multidiscip...

Olezarsen May Reduce Risk for Acute Pancreatitis in Severe Hypertriglyceridemia Olezarsen significantly lowers triglycerides and pancreatitis risk in severe hypertriglyceridemia, with a favorable short-term safety profile.

Olezarsen reduces triglyceride levels and is linked to a substantial reduction in acute #pancreatitis risk, making it a promising treatment option.
www.gastroenterologyadvisor.com/news/olezarsen-may-reduc...

No Surveillance Needed After Curative ESD in Low-Risk T1 Colorectal Cancer Endoscopic submucosal dissection alone results in excellent outcomes among individuals with low-risk T1 CRC.

Endoscopic submucosal dissection is sufficient for low-risk T1 #ColoRectalCancer. Additional operations in high-risk cases reduce recurrence but don't improve survival.
www.gastroenterologyadvisor.com/news/no-surveillance-nee...

Antibiotic Use for GI Infection May Increase IBS Risk Antibiotic use, especially during GI infections, increases IBS risk, supporting cautious prescribing despite study heterogeneity.

Antibiotic use is linked to a higher risk of developing #IrritableBowelSyndrome, most notably after gastrointestinal infections.
www.gastroenterologyadvisor.com/news/antibiotic-use-for-...

IFA Positivity Linked to Anemia Risk in Autoimmune Gastritis Anemia is present in approximately 40% of individuals with autoimmune gastritis and is significantly linked to anti-intrinsic factor antibody positivity.

Anti-intrinsic factor antibody positivity is an independent risk factor for anemia in autoimmune #gastritis.
www.gastroenterologyadvisor.com/news/ifa-positivity-link...

Postoperative CD Reprogression Unrelated to Preoperative Phenotype Postoperative reprogression to stricturing or penetrating complications is not linked to preoperative disease phenotype in CD ileocecal resection.

Preoperative disease phenotype does not predict postoperative reprogression in #CrohnDisease.
www.gastroenterologyadvisor.com/news/postoperative-cd-re...

Darvadstrocel Not Linked to Remission at 24 Weeks for Complex Perianal Fistulas in CD Darvadstrocel does not significantly improve remission rates among individuals with Crohn disease with perianal fistulas.

Compared with placebo, #darvadstrocel is not superior in efficacy for inducing remission in complex perianal fistulas in #CD.

Read More: https://bit.ly/41J9ghd

Cardiometabolic Risk Increases Morbidity, Not Mortality, in ALD Cardiometabolic risk factors do not increase 5-year mortality in ALD but are linked to higher risk for liver complications, cardiovascular events, and infections.

Cardiometabolic risk factors in alcohol-associated #liverdisease identify a higher-risk phenotype characterized by substantially increased morbidity, despite no significant difference in overall mortality.
www.gastroenterologyadvisor.com/news/cardiometabolic-ris...

Prepregnancy HBV Vaccination Linked to High Infant Antibody Response Children of mothers vaccinated against HBV prior to pregnancy achieve significantly higher antibody responses after routine infant vaccination.

Maternal #HepatitisB vaccination does not change overall infant seroprotection rates but is linked with a stronger, higher-titer antibody response.
www.gastroenterologyadvisor.com/news/prepregnancy-hbv-va...

In TNF-Exposed UC, Upadacitinib May Be a Corticosteroid-Sparing Treatment Strategy Upadacitinib vs ustekinumab reduced steroid use in TNF-exposed UC, with similar safety and clinical outcomes at 1 year.

Among patients with #UlcerativeColitis who used anti-TNF agents, upadacitinib was linked to lower corticosteroid use and better steroid-free outcomes than ustekinumab.
www.gastroenterologyadvisor.com/news/upadacitinib-a-cort...

Wearable Technology for IBD Management: Early Insights Into Disease Activity Wearable technology for IBD management includes the ability to detect flares early and support continuous, data-driven disease monitoring.

Wearable devices are emerging as a tool for continuous physiologic monitoring in #IBD, with potential to improve early detection and disease management.

Read More: https://bit.ly/4bQCbpG

PPI Users Have More Nonvariceal Upper GI Bleeding, but Superior Outcomes Proton pump inhibitor users vs nonusers have a higher incidence of nonvariceal upper gastrointestinal bleeding but more favorable outcomes.

Although #NVUGIB occurs more frequently among individuals receiving treatment with PPIs, these patients have less severe disease and more favorable outcomes.
www.gastroenterologyadvisor.com/news/ppi-users-have-more...

What Is Postinfectious IBS? An Overview of the Gut-Brain Interaction Disorder Postinfectious IBS is a condition that occurs after a GI illness. Our overview covers symptoms, treatment, and more.

What is #PostinfectiousIBS? Our easy-to-read fact sheet for patients provides an overview of postinfectious IBS symptoms, diagnosis, treatment, and more. #IBSAwarenessMonth

Read and download the full article: www.gastroenterologyadvisor.com/factsheets/postinfectiou...

Pediatric Autoimmune Liver Disease Associated With Lower Quality of Life Children with autoimmune liver disease have a reduced quality of life, especially emotionally and in school.

Pediatric #AutoImmuneLiverDisease is linked to a decreased quality of life and is driven more by symptoms and treatment factors than disease duration.
www.gastroenterologyadvisor.com/news/pediatric-autoimmun...

Preoperative and Postoperative TNFi Use in CD Associated With Improved Outcomes Perioperative TNF inhibitor use is associated with improved outcomes among patients with CD undergoing bowel resection.

Perioperative TNFi therapy is safe and efficacious for #CrohnDisease, reducing staged surgery and postoperative endoscopic recurrence without increasing complication risk.
www.gastroenterologyadvisor.com/news/preoperative-and-po...

Fundamental Motor Skill Proficiency Linked to Lower Obesity Risk in Children There is a significant inverse association between children’s fundamental motor skills and weight status, with children of normal weight consistently performing better than those with obesity.

There is a significant inverse association between children’s fundamental motor skills and weight status, with children of normal weight consistently performing better than those with #obesity.

Read More: https://bit.ly/4tpviBx

Model Improves Diagnosis and Treatment of In-Hospital HCV Cases A CDC-coordinated care model improved HCV testing, treatment rates, and time to therapy, supporting scalable strategies for HCV elimination.

A coordinated, hospital-based follow-up model significantly improves #hepatitisC diagnosis, treatment uptake, and time to care, offering a scalable pathway to elimination.
www.gastroenterologyadvisor.com/news/model-improves-diag...

CBT Underutilized in DGBI Despite High Patient Receptiveness Most adults with DGBI perceive CBT as beneficial. However, significant barriers, such as limited access, cost, and low referral rates persist.

Although many patients with #DGBIs believe #CBT can be helpful, it is substantially underutilized due to access barriers and low health care professional referral rates.

Read More: https://bit.ly/4m91WVq

Lidocaine-Based Multimodal Therapy Accelerates Symptom Relief for Hemorrhoids A lidocaine-based multimodal regimen led to faster symptom relief, improved quality of life, and reduced need for analgesics in those with hemorrhoids.

A lidocaine-centered multimodal conservative regimen provides earlier, better symptom relief and reduced health care utilization than standard care for #hemorrhoids.
www.gastroenterologyadvisor.com/news/lidocaine-based-mul...

CBT for IBS: A Frontline Treatment, Not Adjunct Therapy Cognitive behavioral therapy (CBT) for IBS is an effective way to target the brain-gut axis and improve symptoms, but few patients receive it.

We spoke to Jeffrey Lackner, PsyD, a pioneer in research on #cognitivebehavioraltherapy for #irritablebowelsyndrome (#IBS) to discuss barriers in access to treatment and the need for increased awareness. #IBSAwarenessMonth

Read more: www.gastroenterologyadvisor.com/features/cbt-for-ibs/

Nearly 30% of IBD Patients Have Moderate-to-Severe Disability Worldwide Nearly one-third of patients with IBD experience moderate-to-severe disability, with higher risk in active disease and Crohn disease.

Moderate-to-severe disability affects about 30% of patients with #IBD and remains common even during remission.
www.gastroenterologyadvisor.com/news/one-third-ibd-patie...

@FDA approved #Foundayo™ in combination with a reduced-calorie diet and increased physical activity to reduce/maintain excess body weight in adults with obesity or overweight in the presence of at least 1 weight-related comorbid condition.

Read More: https://bit.ly/4scalsM

AI Does Not Increase Gastric Neoplasm Detection Rate in EGD AI-assisted endoscopy improved quality metrics but did not significantly increase gastric neoplasm detection after centralized pathology review.

AI does not significantly improve #gastricneoplasm detection after rigorous pathology review, though it enhanced procedural quality.
www.gastroenterologyadvisor.com/news/ai-does-not-increas...

AGA Clinical Practice Update on Gastric Mucosal Polyps Detection and Treatment The AGA has released guidelines on gastric polyps treatment, emphasizing endoscopic evaluation, appropriate resection, and follow-up.

Practice Update: Gastric Mucosal Polyps

Read More: https://bit.ly/47C9dHE

Hemostatic Powder Comparable to Standard Endoscopic Therapy in Nonmalignant NVUGIB Hemostatic powder reduces bleeding during EGD but demonstrates similar rebleeding rates vs standard therapy.

#Hemostatic powder may reduce immediate bleeding during endoscopy in some nonmalignant upper #GI bleeding cases, but overall outcomes are similar to standard endoscopic therapy.

Read More: https://bit.ly/4sNHdsA

Upper GI Involvement in CD Has Limited Effect on Response and Remission Rates Upper Crohn disease is rare and shows similar treatment response and outcomes to extensive Crohn disease.

#Hypertension, #diabetes, and #obesity were estimated to rise significantly among adult women in the United States by 2050.

Read More: https://bit.ly/3NGInqT

Upper GI Involvement in CD Has Limited Effect on Response and Remission Rates Upper Crohn disease is rare and shows similar treatment response and outcomes to extensive Crohn disease.

Upper gastrointestinal involvement in #CD appears uncommon and generally does not require different immunosuppressive treatment strategies.

Read More: https://bit.ly/47yq51I

Excess Prepregnancy Parental Adiposity Linked to Offspring MASLD Prepregnancy parental obesity significantly increased risk for metabolic dysfunction-associated steatotic liver disease in offspring.

While federal officials pushed for expanded nutrition curricula, some clinicians argued that limited patient encounter times and systemic barriers like food costs were primary obstacles to effective nutritional intervention.

Read More: https://bit.ly/4uCauZ6