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Posts by Rebecca Clark

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🗞️ In two new publications, members of @tb-lshtm.bsky.social explore the gaps that people living with #TB can fall into at the beginning or end of the care pathway, including post-TB #PublicHealth

Read more 🔽
www.lshtm.ac.uk/research/cen...

2 weeks ago 4 4 0 0

A year after my last day with @lshtm-tbmod.bsky.social my work on modelling the impact of increasing men's access to care and reducing excess risk of TB has gone live @commsmed.nature.com

www.nature.com/articles/s43...

3 weeks ago 4 6 0 0
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Acceptability of a proposed new tuberculosis vaccine among people deprived of liberty in Brazil Tuberculosis (TB) persists as a global threat, with unequal burden across populations. New TB vaccines are in development, and people deprived of libe…

Happy to see that our work in TB vaccine acceptability in Brazilian prions is on!

6 male and 2 female prison units at 6 Brazilian cities, >900 individual interviews, with 95.2% of acceptance to a new proposed TB vaccine. However...

#TBsky #IDsky
www.sciencedirect.com/science/arti...

1 month ago 12 3 1 0

Our analysis of #TB exposure and transmission patterns is now in @pnas.org. @petedodd24.bsky.social and I found a majority of TB transmission globally is attributable to contact with adult men, while contributions to transmission by age are more variable across regions.
www.pnas.org/doi/10.1073/...

1 month ago 10 8 0 0
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🗞️ Recent study with @lshtm-tbmod.bsky.social modelled the potential impact of funding cuts to TB #PublicHealth initiatives from international donors

Already implemented USAID cuts could cost $7.5 billion (USD) for healthcare systems & people living with TB

Read 🔽
www.lshtm.ac.uk/research/cen...

1 month ago 11 11 0 1
Post-doctoral Research Fellow in Vaccine Impact Modeling, Global Health, School of Public Health - Boston, MA, United States - Boston University Find a career with Boston University

🚨JOB OPPORTUNITY! Apply to come work with me on vaccine impact modeling (specifically #HPV and #RSV) @busph.bsky.social! jobs.silkroad.com/BU/External/...

4 months ago 1 1 0 0
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The potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries: A modeling study In a modelling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of Tuberculosis in low- and middle-income ...

With Nick Menzies and @lshtm-tbmod.bsky.social, our new modeling study estimated how reductions in donor funding could affect the economic burden of #TB on patients, especially among the poorest households journals.plos.org/plosmedicine...

1 month ago 5 5 0 1
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World TB Day Symposium 2026: TB in a changing world
Join us in‑person / online for annual UCL‑TB/LSHTM WTBD Symposium on Tues 24 March 2026
• Beyond the lungs
• Global trends / health systems
• The potential for AI
…& more
www.ucl.ac.uk/tb/events/wo...
@tb-lshtm.bsky.social

1 month ago 3 2 0 0
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The potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries: A modeling study In a modelling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of Tuberculosis in low- and middle-income ...

New @plosmedicine.org

"eliminating all external funding for tuberculosis could lead to nearly 80 billion US dollars in additional household costs and more than 40 million extra households facing catastrophic costs"

journals.plos.org/plosmedicine...

1 month ago 19 6 0 1

Shout out to co-authors below:

@hiratanv.bsky.social
Tom Sumner
@kchorton.bsky.social
@top-j.bsky.social
Roel Bakker
Kirankumar Rade
Vidya Mave
Mark Hatherill
Gavin Churchyard
@reinhouben.bsky.social
@richardwhite321.bsky.social

1 month ago 2 0 0 0
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Many thanks to all co-authors and others in the TB vaccine world for useful discussions on scenarios, implications, and potential ideas for future work (coming soon!)

@cmmid-lshtm.bsky.social
@lshtm-vaccines.bsky.social
@tb-lshtm.bsky.social
@lshtm-tbmod.bsky.social

1 month ago 2 0 1 0
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Estimating the population impact of new tuberculosis vaccines depending on efficacy against infectious asymptomatic tuberculosis: A modelling study Hira Tanvir and colleagues estimate the potential impact of new tuberculosis vaccines under three scenarios of efficacy and conclude that to achieve the greatest impact, vaccines must prevent asymptom...

Our recent modelling study found that the estimated impact of new TB vaccines depends on the efficacy to prevent infectious asymptomatic TB. Read more in our paper out now in @plosmedicine.org!

journals.plos.org/plosmedicine...

1 month ago 15 13 1 0
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The potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries: A modeling study In a modelling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of Tuberculosis in low- and middle-income ...

In this modeling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries 🧪 #MedSky #TB
plos.io/4ryyBFX

1 month ago 15 15 0 2
The effects of war on digital adherence technology engagement for TB treatment in Ukraine SUMMARYBACKGROUNDThe Russian invasion of Ukraine in February 2022 has disrupted TB care. We examine the effects of the war on people with drug-susceptible TB (PWTB) and health care worker (HCW) engagement with a digital adherence technology (DAT).METHODSWe conducted a cluster-randomised trial of a DAT intervention in Ukraine. In the intervention arm, PWTB received a pillbox with a daily treatment reminder. Pillbox openings were captured real-time onto a platform, accessed by HCWs who could add manual doses where relevant. We compared DAT engagement in pre-, early-, and later-war periods.RESULTSFrom June 2021 to 2022, 816 PWTB (32% women, median age 44 years) were enrolled. DAT engagement varied across regions and time period, with a decline in engagement post-February 2022. PWTB DAT engagement was 78%–84% of treatment-days. There was a three- to four-fold increase in unknown dose or delays in manual reporting of adherence (>7 days) post-February 2022 versus pre-war in Mykolaivska and Donetska oblasts and a two-fold increase in Odeska, Lvivska, and Zakarpatska oblasts.CONCLUSIONThe war significantly disrupted DAT engagement, particularly in regions heavily affected by the conflict. Reduced engagement was likely due to migration and communication challenges. There is a critical need for resilient TB care in conflict settings.

We know conflict & crises have severe repercussions for TB; health system disruptions, displacement, food insecurity... In our latest paper we examine the effects of war in Ukraine on engagement with a digital adherence tech by people w TB & health care workers journals.theunion.org/content/ijtl...

2 months ago 10 8 1 0
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Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study Alvaro Schwalb and colleagues conducted a mathematical modelling study to estimate the global burden of viable Mycobacterium tuberculosis--that which can cause disease and be transmitted--to help guid...

1/📢 In our new publication, we estimate that in 2022, 134 million people worldwide had a recent Mycobacterium tuberculosis (Mtb) infection and were at high risk of progressing to TB disease. Read the full paper in PLOS Medicine (tinyurl.com/mtbinfection). #TBSky

2 months ago 37 25 2 2
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Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study Alvaro Schwalb and colleagues conducted a mathematical modelling study to estimate the global burden of viable Mycobacterium tuberculosis--that which can cause disease and be transmitted--to help guid...

In this mathematical modeling study, Alvaro Schwalb and colleagues estimate the global burden of viable Mycobacterium tuberculosis—that which can cause disease and be transmitted—to help guide disease prevention efforts 🧪 #tuberculosis #MedSky
plos.io/4aqzIQV

2 months ago 11 6 0 2
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Insights on the implementation strategies for a potential new tuberculosis vaccine in South Africa Several tuberculosis (TB) vaccines intended for adults and adolescents are in late-stage clinical trials, but there is limited research into how a new TB vaccine would be introduced. South Africa is a...

Our new paper on strategies for implementing a potential new #TB #vaccine in South Africa is now published in @plosglobalpublichealth.org!

doi.org/10.1371/jour...

2 months ago 7 10 1 0
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Our Editor’s Choice commentary in @cidjournal.bsky.social finds that reported TB symptoms are an inadequate classifier of disease state, as they are heavily influenced by context and substantial interviewer variability, and may have alternative causes.

Read more here👇🏻

doi.org/10.1093/cid/...

4 months ago 4 3 0 0
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Still time to register! 👇

Join the #WGNV ECR Network - Virtual Coffee Corner on 4 December 2025 to network, share experiences, and talk about #TBvaccine activities of interest.

📅 Date: Thur 4 Dec 2025
🕑 Time: 9:00 am EDT / 3:00pm CET | 4:00pm SAST | 7:30 pm IST
🔗 tinyurl.com/kj7kuuft

4 months ago 0 0 0 0
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Another successful "Intro to TB Modelling" course in Copenhagen at #WLHC2025. Over 70 joined to learn about TB modelling!

Followed by the now-traditional TB Modelling and Analysis Consortium social, which was also very well-attended and a lot of fun.

4 months ago 12 7 1 1
2026-27 Project (Sumner & Clark & Grint) - MRC London Intercollegiate Doctoral Training Partnership Studentships Mathematical modelling and clinical trial simulation of TB prevention SUPERVISORY TEAM Supervisor Dr Tom Sumner...

#5 Mathematical modelling and clinical trial simulation of TB prevention
mrc-lid.lshtm.ac.uk/2026-27-proj...
with Tom Sumner, @raclark18.bsky.social & @danieljgrint.bsky.social

5 months ago 1 3 0 0
2026-27 Project (Clark & White) - MRC London Intercollegiate Doctoral Training Partnership Studentships How should countries deliver new TB vaccines when risk factors are considered? SUPERVISORY TEAM Supervisor...

#3 How should countries deliver new TB vaccines when risk factors are considered?
mrc-lid.lshtm.ac.uk/2026-27-proj...
with @raclark18.bsky.social & @richardwhite321.bsky.social

5 months ago 1 3 1 0

Come join us for a PhD in the TB Modelling Group!

5 months ago 1 1 0 0
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Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative Undernutrition is a key driver of the global tuberculosis epidemic, increasing the risk of people developing tuberculosis disease and of poor outcomes in those who do.1 Each year, WHO publishes estima...

New comment:

Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative

www.thelancet.com/journals/lan...

5 months ago 8 10 0 0
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What’s a #UnionConf without the TB modelling course? Packed room again for a long day of intro to modelling.
@lshtm-tbmod.bsky.social @tb-mac.bsky.social #WCLH2025 #TBSky

5 months ago 17 5 1 1
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Perhaps the most important collaboration at #UnionConf2025?

WHO STOP TB’s Hello Kitty met the LSHTM TB Modelling Group’s bunny mascot “Bugs” today 🐰

Shout out to @stoptb.bsky.social and @lshtm-tbmod.bsky.social for making TB epidemiology both rigorous and accessible. #EndTB #WCLH2025

5 months ago 9 2 0 1
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Climate change and tuberculosis: an analytical framework Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in w...

Our framework that informed the @who.int TB & climate change policy brief out now in @lancetrespirmed.bsky.social, exploring the intersections and implications of climate change for the TB epidemic. Key message? TB should be considered a climate-sensitive disease
www.thelancet.com/journals/lan...

5 months ago 22 18 1 0
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Announcement Awardees | TBVI Awards 2026 - TuBerculosis Vaccine Initiative Announcement Awardees | TBVI Awards 2026

✨ I’m so honoured to have been awarded one of this year’s TBVI Awards! ✨

I’m truly grateful for this recognition and excited for the opportunity to showcase my research at the TBVI Annual Meeting in January 2026.

#TBVI #tuberculosis #vaccines

tbvi.eu/announcement...

5 months ago 9 1 0 0
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Body mass index and tuberculosis risk: an updated systematic literature review and dose–response meta-analysis AbstractBackground. The relationship between nutritional status and tuberculosis is critically important but poorly understood. We extended a 2009 review c

We think our recent review provides a better estimate of the RR leading to a much higher PAF, demonstrating the importance of addressing undernutrition to prevent TB.
academic.oup.com/ije/article/...

5 months ago 3 2 1 0
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Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative Undernutrition is a key driver of the global tuberculosis epidemic, increasing the risk of people developing tuberculosis disease and of poor outcomes in those who do.1 Each year, WHO publishes estima...

“Wow, I saw in the last GTB report undernutrition is much less important for TB than we previously thought” I hear you say…
Well, no. We think this is an underestimate, & as much as 28% of TB could be attributable to undernutrition – see our latest comment here: www.thelancet.com/journals/lan...

5 months ago 8 10 1 1