Blog post on "The AI Rewrite Dilemma": lh3.github.io/2026/04/17/t...

Some Swedish hockey players demonstrate various winter Olympic sports. 😁

(sound on)

#Olympics

In remembrance of Peer Bork  | EMBL EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.

very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...

I want to spell this out in case the implications aren't clear:

This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.

The file allowed this. Cut that - cut off all tools the public & others were using.

Can an AI tool help us better understand the origins of cancer?

Researchers from EMBL's Korbel Group have developed a new AI method – MAGIC – which, through a game of molecular laser tag, is shedding light on how chromosomal abnormalities form in cells.

www.embl.org/news/science...

Team Leader – Genomics Core Facility and Method Development Are you ready to lead a cutting-edge Genomics Core facility while developing state of the art genomics methods? Join us at EMBL! We are seeking talented scientists to develop and lead a cutting-edge G...

Open Team Leader position @embl.org to head & reshape our Genomics Core facility. Interested in providing & developing state-of-the art omics tech to a wide community? A very vibrant, dynamic place to work with fantastic colleagues. Closing Sept 30th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

We’re looking for curious, innovative science leaders at EMBL Heidelberg! 🔬🧬🦠

Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.

Take a look at these four open positions 👇

Group Leader - Genome Biology Unit Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...

To all post-docs: The Genome Biology dept ‪@embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Very nice summary of our latest paper by @samarendra-pani.bsky.social Thanks for all your hard work and outstanding contributions to this project!

Complex genetic variation in nearly complete human genomes - Nature Using sequencing and haplotype-resolved assembly of 65 diverse human genomes, complex regions including the major histocompatibility complex and centromeres are analysed.

Two papers in today's issue of @nature.com ‬: 1) we assemble 65 genomes to near completion, including centromeres and the MHC. tinyurl.com/3huhax6w. 2) we sequence 1,019 genomes from the 1kGP with long reads, revealing SVs down to low allele frequencies tinyurl.com/wbx3we9x.

EMBL researchers and their collaborators have provided exciting new insights into human genetic variation by building upon the 1000 Genomes Project dataset.

The two studies constitute what may be the most complete overview of the human genome to date.

www.embl.org/news/science...

GitHub - gpertea/gffread: GFF/GTF utility providing format conversions, region filtering, FASTA sequence extraction and more GFF/GTF utility providing format conversions, region filtering, FASTA sequence extraction and more - gpertea/gffread

Maybe gffread github.com/gpertea/gffr... or the good old kentUtils ?

Sorry guys, I can't come out to play, I have to read the new paper by Gene Meyers, Richard Durbin and Chenxi Zhou!

Now published! Note that since Vikram's original post (quoted here), he's made it easy to dynamically update a set of multi-MUMs (e.g. when more genomes are added to a pangenome) and to find multi-MUMs for huge collections like HPRCv2 genomebiology.biomedcentral.com/articles/10....

The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples

SPECIAL ISSUE Part 2! This month @genomeresearch.bsky.social publishes a diverse collection of articles offering novel biological and clinical insights gained using long-read DNA and RNA sequencing technologies and other long molecule approaches.
tinyurl.com/Genome-Res-3...

Course at EMBL-EBI Cancer genomics and transcriptomics 12 - 16 May 2025 Virtual

If you’re a #cancer researcher looking to use high throughput sequencing and single-cell technologies, then this course is for you! Make sure you've applied by 9 Feb:
www.ebi.ac.uk/training/eve...

Some financial assistance is available. See the course page for more info.

#OncSky #GeneSky 🧪🖥️🧬

On #WorldCancerDay, we feature how EMBL’s research & services are aiding the fight against cancer.

From prediction methods to studying cancer mechanisms – every discovery advances our collective knowledge about this global health challenge.

👇 Learn more:
www.embl.org/news/tag/can...

🧪 #cansky

EMBL International PhD Programme Summer Recruitment Applications open. Applications close 10 March 2025.

Recruitment for the EMBL International PhD Programme is officially open! 🔊

At EMBL, we train young scientists to become skilled and creative future leaders in academia, industry & other sectors. Start your career in the life sciences with us!

www.embl.org/about/info/e...

🧪 #AcademicSky #careers

Fakten sind das Rückgrat unserer Demokratie - Online-Petition Liebe Mitbürgerinnen und Mitbürger, als Wissenschaftlerinnen und Wissenschaftler arbeiten wir täglich daran, die Grundlagen für fundierte Entscheidungen und Innovationen zu schaffen – basierend auf üb...

"Fakten sind das Rückgrat unserer Demokratie."

Hier ein Aufruf, der gerne geteilt werden darf:

www.openpetition.de/petition/onl...

Around genomics, I am looking forward to large scale long read datasets - both Oxford Nanopore and PacBio (COI: I am long established consultant to Oxford Nanopore) where we can get "full" genome representation both for germline and somatic cases. This will transform repeat+structural variant calls

I also deactivated mine.

12 moments of philanthropy: #12 New frontiers in childhood cancer research | EMBL The Athenaeum Dietrich Götze Stiftung fuels impactful EMBL research that aims to better understand treatment-resistant childhood leukaemia.

Athenaeum Dietrich Götze Stiftung has generously supported EMBL’s childhood leukaemia research. 🧪

Scientists hope that cell markers they discovered help to understand disease relapse better and lead to more effective treatment. #EMBL50 #MolBiol #Leukemia

www.embl.org/news/connect...

Before Christmas I did threads on the application areas of genomics in rare disease (bsky.app/profile/ewan...) and in common disease (bsky.app/profile/ewan...) - now I am going to focus on Cancer genomics

Sometimes you just have to persevere through negative reviews. Reviewers, please be kind :) #methodsmatter bit.ly/gs2-scholar

Programme at a Glance Pre-conference courses Thursday, May 22, 2025 & Friday, May 23, 2025 - TBA Conference programme Saturday, May 24, 2025 08:30 - 10:00 Educational Sessions E01 E01 Single cell genomics and diseases W...

The preliminary #eshg25 program is online. Stellar line-up of invited speakers - full breadth of our amazing field. Grateful to a wonderful SPC @eshg that made this possible. See you all in Milan next year!

2025.eshg.org/programme-at...