Are you interested in achieving efficient silencing of transposable elements using CRISPRi? 🧬 🧫
Go ahead and have a look at this STAR protocols where Adami et al. share all the tips & tricks they use in the Jakobsson lab.
@anitaada.bsky.social @raquelgarza.bsky.social @jakobssonlab.bsky.social
Single-cell atlas of striatal cells from early-stage Parkinson's mouse models and Parkinson's patients.
CRN Teams Cragg & Jakobsson's new #preprint maps the cell-type–specific transcriptional landscape of the parkinsonian striatum in mouse models and human Parkinson's stages, revealing widespread gene expression changes and resilient neuron subtypes amid progressive dopamine loss 🧪
🔗 bit.ly/4ju4MmS
Have a look at two of the latest outputs from CRN Team Jakobsson, examples of true team effort and collaboration 🧠 💫
We are grateful to @asapresearch.parkinsonsroadmap.org for making this research possible!
@jakobssonlab.bsky.social @kirkebylab.bsky.social @mollygale.bsky.social #RogerBarkerLab
Agnete Kirkeby’s 2025 Edinburgh Parkinson’s Lecture is available online: youtu.be/EtuRHdPX4rc?...
She delivered a masterclass on stem cell therapies for #Parkinsons. A PwP told me : “I was expecting not to understand much, but I understood everything!” @kirkebylab.bsky.social @parkinsons.org.uk
Always a joy to join #EMBOMobileGenome -A week full of cool nature’s quirks and science along the friendliest crowd 🧬 Happy to have shared our work on ERVs in human brain evolution (talk by @jakobssonlab.bsky.social) and Parkinson’s disease (poster by yours truly) 🧠
#ASAP @jakobssonasap.bsky.social
📣 New preprint from the Jakobsson lab!
We describe a detailed protocol to inhibit the expression of transposable elements in human pluripotent stem cells, developed thanks to @asapresearch.parkinsonsroadmap.org funding.
Special shoutout to @anitaada.bsky.social!
www.biorxiv.org/content/10.1...
@raquelgarza.bsky.social from the Jakobsson Lab presented our recent work on single-cell omics (transcriptomics+ proteomics) within our ASAP project at the SciLifeLab Lund day. This work is being done in collaboration with #BioMS and @scilifelab.se. We are looking forward to the discoveries ahead 🌟
Have a look at the new preprint from Team Cragg! We are very happy of having contributed to this great work as a collaboration within the ASAP-CRN network 🧠🔬
@craggasap.bsky.social @asapresearch.parkinsonsroadmap.org
🚨 Have a look at our new preprint: www.biorxiv.org/content/10.1...
A highly collaborative effort where we show that transposable elements are directly linked to a cell-type and region specific inflammatory state in Parkinson’s Disease.
@asapresearch.parkinsonsroadmap.org
🧬 🧠A new Cell Genomics study by researchers at @lunduniversity.bsky.social (@jakobssonlab.bsky.social & @jakobssonasap.bsky.social) shows the non-coding genome is active in early brain development & may be relevant for understanding brain disease.
Read more: www.stemcellcenter.lu.se/article/why-...
Team Jakobsson gathered in southern Sweden for a few inspiring days discussing PD, transposable elements and future plans. We even squeezed in a hike and enjoyed some beautiful views ☀️🌊 @jakobssonlab.bsky.social @kirkebylab.bsky.social @mollygale.bsky.social @asapresearch.parkinsonsroadmap.org
These past 2 months as a visiting scholar at KU Leuven flew by! It has been so enriching to work side by side with #TeamVoet on @jakobssonasap.bsky.social research into Transposable Elements & Parkinson’s Disease 🧠🧬 Excited for what’s next!
#ParkinsonsDisease #MJFF #ASAP #CRN #TransposableElements
@jakobssonlab.bsky.social @raquelgarza.bsky.social @mollygale.bsky.social
Last week, some of us from Team Jakobsson had a great time in Arizona at the 2025 CRN Collaborative Meeting! Plenty of insightful talks and networking. Shoutout to @kirkebylab.bsky.social for a fantastic talk on PSC-based therapies and models of PD 🌟🧬🏜️ #CRNPhoenix2025 @asapresearch.bsky.social
Popcorn worthy research at #CRNPhoenix2025 with
@jakobssonasap.bsky.social 🍿
#ParkinsonsDisease #PD #TEsky
🧠🔬 Great meeting last Friday in Copenhagen between the Kirkeby and Jakobsson labs — exciting experiments coming up to investigate transposons in PD in vitro models! @asapresearch.bsky.social @kirkebylab.bsky.social @jakobssonlab.bsky.social
🚨 New pre-print from Team Jakobsson! LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development.
This work was led by @anitaada.bsky.social, @raquelgarza.bsky.social and @jakobssonlab.bsky.social from the Jakobsson Lab.
www.biorxiv.org/content/10.1...
🌟🧠🧬 Exciting meetup in Cambridge with the Barker, Jones and Jakobsson labs! Great discussions, fresh ideas, and plenty of plans for the next steps.
@asapresearch.bsky.social @jakobssonlab.bsky.social
We're thrilled to announce that our project has been funded by @asapresearch.bsky.social in partnership with the Michael J. Fox Foundation! 🚀 Excited to continue exploring the role of transposable elements in Parkinson’s disease. Learn more here:
www.lunduniversity.lu.se/article/52-m...
Hi! Thanks for creating this. We'd like to be added 😊
Hi! Thanks for creating this. Could you add to the list? We study TEs in Parkinson's disease.