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Posts by Mark Hirsch

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Parkinson’s disease and bone health: why I think screening should be mandatory. Gandhi and colleagues describe in a new paper that just dropped in the Journal of Parkinson’s Disease why early bone health assessment should be part of routine Parkinson’s care, and I strongly agree.

1 month ago 5 2 0 0
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Can we bring Parkinson’s physical therapy into the living room? A new telerehabilitation feasibility trial says YES. New paper in the Journal of Parkinson’s Disease how individualized real time physiotherapy delivered via videoconference may improve activity and motor outcomes in early Parkinson’s.

2 months ago 2 1 0 0
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Spirituality and neurological diseases like Parkinson’s and Alzheimer's. Could faith, meaning and purpose shape how folks cope and heal? Spirituality can play a powerful role in neurologic disease care, including PD and AD and how health care providers can better address it as part of whole care.

1 month ago 5 2 0 0
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The people have spoken and the company is listening. We have reached a public health milestone.
"This moment proves that advocacy, data and courage can change the trajectory of disease.”
www.pdplan.org
www.theguardian.com/environment/...

1 month ago 7 3 0 0
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Why is Parkinson disease growing worldwide? The 'bathtub analogy' explains the surge. A bathtub analogy means imagining disease cases like water filling a tub where inflow, outflow and drainage determine how high the water rises.

1 month ago 3 1 0 0
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Adaptive DBS and the future of walking: Proceedings is out from the XIII annual DBS Think Tank. The meeting gathered engineers, neuroscientists, industry partners and health care providers to discuss the evolving landscape of DBS, including adaptive stimulation for walking and more.

1 month ago 4 2 0 0
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The more active you are, the easier it is to manage your Parkinson's symptoms.

But some symptoms - like rigidity, anxiety and risk of falls - can make exercise daunting.

👉 Read our top tips on how to exercise safely with Parkinson's: buff.ly/5BHF8QB

#Parkinsons #Parkinson

9 months ago 2 2 0 0
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🚨 NEW: we're proud to launch our new Parkinson's Passport!

Planning a holiday? ✈️ The Parkinson's Passport gives you a handy record of your important medical info, making travel with #Parkinsons less stressful.

👉 Download in French, English, Italian or German: buff.ly/8IbHN0Z

#Parkinson

11 months ago 20 8 0 0
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A new important lens on demoralization in Parkinson’s disease. Do you have a plan if you encounter demoralization? Spoiler alert: Demoralization affects about 1 in 5 w/ Parkinson's. This is a must-read article. Demoralization is tragically under-recognized. #parkinson @parkinsondotorg.bsky.social

9 months ago 5 1 0 1
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Is it time to tame the brain’s fire? Neuroinflammation is emerging across Parkinson's, Alzheimer's, neurodegeneration and beyond. An important new Science article from Shi and colleagues pulls back the curtain on neuroinflammation. Could be a silent driver of destruction in Parkinson’s and beyond?

10 months ago 7 4 0 0
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We have the guidelines, so why aren’t we referring to PT and other therapies for Parkinson’s? Let me say this clearly: There are strong evidence-based guidance to refer people w/ Parkinson’s to physical therapy early and regularly. Yet, it’s not happening. Why? #parkinson #physicaltherapy

10 months ago 1 1 0 0
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Constipation in Parkinson's is a huge unmet challenge. We must unclog the pipeline. Great article in HealthCentral this week shining light on this topic by Cheyenne Buckingham. She interviewed a few of us in the field and summarized approaches to treatment. #parkinson #constipation

9 months ago 1 1 0 0
Text over an abstract background, text reads: 

Disability technology
How data and digital assistive technologies can support independent, fulfilled lives. 

Read the report online. 

The Royal Society

Text over an abstract background, text reads: Disability technology How data and digital assistive technologies can support independent, fulfilled lives. Read the report online. The Royal Society

Disabled people should be involved from the outset in developing digital tools and services that are fundamental to work, life and play to maximise the transformative benefits they can bring says our new report on #DisabilityTechnology, released today.

9 months ago 23 12 4 2
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The most complex disease in medicine is Parkinson's? YES.
- Multiple organ systems.
- Not a single disease.
- A single biomarker or diagnostic test exists: no
- Disease course is highly variable.
- Complicated regimens.
- Lot's of different symptoms, dopamine awakening, DBS and beyond.

11 months ago 6 2 0 0
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#WorldParkinsonDay!
Collaboration is key. Let's take a moment to reaffirm that we will double our efforts for a cure to #Parkinsons in this moment!

1 year ago 0 0 0 0
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Parkinson's cases will double to 25 million by 2050, BMJ study says - Parkinson's Europe The study looked at the the factors driving changes in Parkinson's cases, suggesting ageing populations will see a 112% rise in prevalence.

parkinsonseurope.org/2025/03/06/p...

1 year ago 0 0 0 0
Citius, Fortius, Altius—Understanding Which Components Dr... The expression “citius, fortius, altius” (Latin for “fast...

Check out the amazing Bas Bloem discussing: Citius, Fortius, Altius—Understanding Which Components Drive Exercise Benefits in Parkinson Disease https://ja.ma/3H4JzMG via @JAMANeuro part of @JAMANetwork @basbloem @DrISubramanian

4 years ago 1 1 0 1
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Today is #InternationalWomensDay ❤️

We're proud to mark the day with @salsbergmathews.bsky.social, who has released new illustrations of the Five Stages of Parkinson's (which typically depict older white men) featuring a diverse range of women.

Find out more: buff.ly/VPYHHFw

#IWD2025 #Parkinsons

1 year ago 20 11 0 2
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Parkinson's, in my opinion, is the most complex disease in clinical medicine. Though it is nice to see these evidence-based reviews, we should keep our eye on the 'ball.' The ball is dynamic, and in Parkinson's will fluctuate over time, and especially with disease progression. Listen to the person.

1 year ago 10 2 0 0

Have an idea for a short film
on patient scientists

1 year ago 0 0 0 0
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📋 If you've taken part in clinical trials, you'll probably have completed questionnaires (or PROMS - Patient-Reported Outcome Measures) about how you perceive your trial experience.

Our Strategic Director Amelia has co-authored a paper about how to improve this process: https://buff.ly/41hdMTG

1 year ago 3 1 0 0
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In case you need this today 💙

1 year ago 1 1 0 0
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The idea that manipulating peripheral nerve afferents as a treatment for tremor is not crazy, however it needed to be tested. For this device, a highly controlled study revealed to us that vibrotactile stimulation failed to improve tremor.

1 year ago 6 2 0 0
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We’re thrilled to hear from Dr. Andreas Horn, this year’s Brain Stimulation Early Career Award winner, at #BrainStimConf today! Congratulations on this well-deserved recognition @andreashorn.org #BrainStim2025 @braistimjournal.bsky.social @braincircuits.bsky.social

1 year ago 21 7 1 0

I've been living in a hot spot for 20 years

1 year ago 1 1 0 0
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Should you get a continuous glucose monitoring device to prevent dementia in diabetes, Parkinson's, Alzheimer's and beyond? There is rising evidence. Historia vero testis temporum – history is the the witness of the ages – and it is thus time for researchers to put this to to the test.

1 year ago 2 1 0 0
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I've been living in a hot spot for 20 years

1 year ago 1 1 0 0
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Parkinson's disease progresses however levodopa does not stop working. There are long-term benefits. Levodopa response over time was documented in this study. Response to levodopa did not weaken after a 4-year follow-up in 63 fluctuators. Axial symptoms worsen. prd-journal.com/article/S135...

2 years ago 3 1 0 0
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Do you know the forgotten drugs that block dopamine receptors and worsen Parkinson's?
Amisulpride (Barhemsys)
Metoclopramide (Reglan, Gimoti)
Droperidol (Inapsine)
Chlorpromazine (Thorazine)
Prochlorperazine (Compazine, Compro).
pubs.acs.org/doi/10.1021/...

2 years ago 4 3 1 0