Injury-induced electrochemical coupling triggers organ growth Organ repair and growth rely on coupling tissue-wide membrane depolarization with intracellular proliferative signaling.

New paper alert!🤩Super proud that our story led by superstar postdocs @liujinghui.bsky.social and @nerlielisa.bsky.social is finally out! We found how electrical signals are key for promoting organ regenerative growth!!! A thread 🧵https://www.science.org/doi/10.1126/sciadv.aec0687

Thank youu!! 🥰

Congrats!! 😊

Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration Nature Communications - Adult zebrafish are capable of heart regeneration, but how the collagenous injury site is replaced remains unclear. Here they provide an in-depth analysis of cardiomyocyte...

Very excited to see the first Beisaw lab publication out in its final form 🥳🥳 rdcu.be/ei1I7 if you’re interested in zebrafish heart regeneration and how cardiomyocytes replace the fibrotic injured tissue (spoiler alert: macrophages play an important role), then read it here 👇

Sosyalizm ve sosyal demokraksi aynı şeyler değil. Sosyal demokrasinin amacı kapitalist sistemde daha adil bir toplum yaratmak. Sosyalizmim amacı kapitalizm yıkıldıktan sonra sınıfsız ve eşitlikçi bir toplum. Bunun için de demokrasi ayak bağıdır. Genellikle tek parti devleti her şeyi tekeline alır.

Stoked to present our latest, superbly led by Chris et al & @torres-sanchez.bsky.social We tackled a fundamental problem – how tissues are patterned during development – found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n www.biorxiv.org/content/10.1...

Check out the latest preprint from our lab, led by Aytac Kadir Mutlu, on the role of topographically organized dorsal raphe (DRN) activity in regulating forebrain function and adaptive behaviors! 🧵👇
www.biorxiv.org/content/10.1...

Motile cilia modulate neuronal and astroglial activity in the zebrafish larval brain The brain uses a specialized system to transport cerebrospinal fluid (CSF), consisting of interconnected ventricles lined by motile ciliated ependymal…

Have you ever wondered what role motile #cilia and cerebrospinal fluid (#CSF) play in brain development and physiology? If yes, please check out our latest article now published in Cell Reports and spearheaded by the newly minted Dr D'Gama www.sciencedirect.com/science/arti...

Spatiotemporal control of translation in live zebrafish embryos via photoprotected mRNAs - Communications Chemistry Translation of mRNA into protein is a fundamental process and tightly controlled during development, however, experimentally controlling the mRNA translation remains challenging. Here, the authors dem...

Translation of mRNA can be triggered with spatiotemporal control in zebrafish 🐟 embryos by light ⚡ & FlashCaps 🧪⚗😊 Kudos to all authors and collaborators 🙏👍
www.nature.com/articles/s42...

A Star Protocols graphical abstract of the steps for the preparation, clearing and visualization of adult zebrafish spinal cords, together with alternative uses for these samples (e.g. cryosectioning and immunohistochemistry of reverted sectioned samples).

The first work of my PhD is OUT 🎆
star-protocols.cell.com/protocols/38...

In this work, we share with the community our protocol for preparation, clearing and visualization of adult 🦓🐟 spinal cords structures that has been tested, refined and used quite frequently in our lab.