Protein migration via dissolution of ATP-stabilized condensate in a gradient of AMP We report the condensate-forming tendency of bovine serum albumin (BSA) increases in the presence of adenosine triphosphate (ATP) in macromolecularly crowded media. However, in the presence of adenosi...

pubs.rsc.org/en/content/a...
Our recent article @chemcomm.rsc.org
We showed - ATP results formation of BSA condensate, but AMP does dissolution. Competition betn #hydrotropy of adenosine #kosmotropy of phosphate.. #dialytaxis of condensate result biocatalysis at distal zone. #ActiveBiocollods

Happy to be a part of this collection.
Here is the link of our article: doi.org/10.1039/D5SC...

An information ratchet improves selectivity in molecular recognition… | Nature Nanotechnology YouTube video by SanGiacomoSpazioArte

Here is a video that explains the chemistry behind our recent paper in Nature Nanotechnology

video
www.youtube.com/watch?v=WnZN...

publication
www.nature.com/articles/s41...

news & views (Ouldridge & Mukherjee - thanks !)
www.nature.com/articles/s41...

Here is audio-video summary of @natcomms.nature.com published work. This system demonstrates the importance of the enzymatic conversion for LIDA effect, as injecting the active activator directly (ammonium bicarbonate instead of urea) results in a reaction primarily near the injection center.

A chemoenzymatic reaction-diffusion system with local inhibition and distal activation - Nature Communications Achieving spatiotemporal gating of signals is desirable for mimicking of biological processes, but is challenging to achieve in synthetic systems. Here, the authors report a multicomponent chemoenzyma...

www.nature.com/articles/s41...
Happy to share our latest article published in Nature Communications. #ReactionDiffusion system with Local inhibition Distal Activation..Potential to develop synthetic systems mimicking natural biological pathways with precise spatial and temporal control of signals.🧵

Very nice. Also congratulations for your ERC !!

Congratulations Jake!

Decoding information entropy of fatty acid and phospholipid vesicles via ordering combinatorial output of hydrazones Leveraging information entropy to quantitatively measure the organizational diversity and complexity of different chemical systems is a compelling need for next-generation supramolecular and systems chemistry. It can also be a strategy for digitalizing and enabling the bottom-up development of life-like complex sys

Our latest @chemicalscience.rsc.org Bringing information theory (Shannon entropy) in the realm of suprachem (vesicle-templated combinatorial chemistry) #cheminformatics, quantified information content in fatty acid and phospholipid liposome, relevant to #originoflife
pubs.rsc.org/en/content/a...

Spatial Shifting of Biocondensate Assembly Zone in a Microfluidic Gradient of Dissipative Condition Pursuing non-equilibrium chemistry with (bio)molecules is of utmost importance for the design of life-like dynamic materials that emerge in a constant flux of energy. Herein, we explore spatial local....

Inaugural post at Bluesky with my favourite ChemSystemsChem article. Thanks to the reviewers for critical+constructive review. Here we play with zonal NESS in flow & arresting molecular diffusion in assembly state exploiting dissipative condn. chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1...