Pfizer Lyme vaccine shows more than 70% efficacy but misses key statistical goal There hasn't been an approved Lyme disease vaccine for more than 20 years, after GSK pulled its shot because of a lack of demand.

www.nbcnews.com/health/healt...

New huge (>800,000 people) study in Nature using genomic sequencing data finds association of EBV w/various diseases, including rheumatoid arthritis, MS, IBD, hypothyroidism, and T2D. Detectable EBV viral DNA is associated with 54 HLA alleles and 27 other genomic loci www.nature.com/articles/s41...

Donate to Keep LC Campaign Founder Housed and Medically Stable, organized by Melissa Mazur Friends, Long COVID Campaign Founder Meighan Stone needs our help! … Melissa Mazur needs your support for Keep LC Campaign Founder Housed and Medically Stable

Long COVID advocate Meighan Stone needs our help, please share and donate if you can. Thanks to @phillyphile215.bsky.social for organizing. www.gofundme.com/f/keep-long-...

The sleep aid medication Ambien unfortunately reduced the frequency of norepinephrine pulses and therefore resulted in reduced clearance of waste in the brain

Diagram showing coordinated oscillation of norepinephrine, blood vessel constriction, and intracranial CSF and blood volume during NREM sleep

During deep sleep, norepinephrine oscillation every ~50 sec cause blood vessels to constrict and push CSF through the brain. The frequency of norepinephrine oscillation predicts glymphatic clearance better than duration of REM sleep, deep sleep, or total sleep

Director of NIH neurological disorders institute is ousted, adding to leadership churn Walter Koroshetz, director of the National Institute of Neurological Disorders and Stroke, will soon be leaving his role, STAT has learned. His departure

A @statnews.com exclusive from me: Walter Koroshetz, director of NIH's neurological disorders institute, has been ousted. Yet another example of NIH leadership churn. His departure means that 13 of the agency's 27 divisions will have interim leaders.
www.statnews.com/2025/12/27/n...

40 percent of MRI signals misinterpreted Interpretation of numerous MRI data may be incorrect: blood flow is not a reliable indicator of brain activity.

"40 percent of MRI signals do not correspond to actual brain activity"; "Since tens of thousands of fMRI studies worldwide are based on this assumption, our results could lead to opposite interpretations in many of them.”
www.tum.de/en/news-and-...

Seven Feel-Good Science Stories to Restore Your Faith in 2025 Immense progress in gene editing, drug discovery and conservation are just some of the reasons to be cheerful about 2025

Immense progress in gene editing, drug discovery and conservation are just some of the reasons to be cheerful about 2025

40K views · 2.2K reactions | Talking Again in 2025 I started eating again in 2024. After 11 years not eating a crumb of food or even drinking a drop of water. I got all fluids and nutrition from tu... Talking Again in 2025 I started eating again in 2024. After 11 years not eating a crumb of food or even drinking a drop of water. I got all fluids and nutrition from tubes inserted into my body....

So amazing to see Whitney Dafoe able to speak again www.facebook.com/reel/6513673...

yangtan.mit.edu/new-study-su...

If you’re not already familiar w/ @boltsmag.org, it does terrific journalism at the local level across the U.S. The quality is wonderful and the stories are critical—putting Bolts in your timeline will make you so much more informed. Highly recommend.

And rn following can help fund their work!

The lingering shadow of epidemics: post-acute sequelae across history The SARS-CoV-2 pandemic has drawn global attention to post-acute infection syndromes (PAIS), with millions affected by post-acute sequelae of COVID-19 (PASC, or Long COVID). While Long COVID is newly ...

New review from Akiko Iwasaki outlining the history of chronic illness in the wake of epidemics www.cell.com/trends/immun...

AirFanta air purifiers Official website of AirFanta air purifiers.

FYI - personal laminar flow & regular air filtration devices from @adamwong.bsky.social are on sale right now! I just wore my Air Fanta Wear for the first time at the hospital to supplement my N99 mask, and it was invaluable when I needed to drink water or (sadly) toss my cookies air-fanta.com

Though this has given us the gift of the term “medical fryrmblal” 💀

The role of co-infection in the pathogenesis of acute SARS-CoV-2 infection and development of post-acute sequelae: A perspective Unraveling mechanisms underlying post-acute SARS-CoV-2 sequelae (long COVID) and finding therapeutic solutions require a full understanding of the causative role of SARS-CoV-2 persistence and/or infec...

Nice review from Tim Henrich et al laying out a framework for thinking about how the complex landscape of prior, concurrent, and subsequent microbial infection (viral, microbial, fungal) may interact w Covid infection and whether that might play a role in Long Covid elifesciences.org/articles/106...

The journal doesn’t actually bear the moniker Nature, which is reserved for more prestigious journals. It’s just Scientific Reports, and it’s a journal I never bothered to read when I was a researcher 😅

Scientific Reports is a crap journal. Impact factor isn’t everything (some good specialist journals score low bc the field is small, reviews journals score high bc of high citation rate, etc) but Scientific Reports’ IF is only 3.9 — compare to Nature Medicine=50, Nature=48.5, Science=45.8, Cell=42.5

Why acute infections can lead to neurodegeneration Researchers are uncovering the mysteries of why early-in-life acute infections can lead to neurodegenerative diseases in later years.

Infection Connections: How past microbial incursions can lead to neurodegenerative diseases
stanmed.stanford.edu/infections-l...

@polybiorf.bsky.social is holding their Fall Research symposium tomorrow (Fri Nov 14). Register here to attend virtually —https://polybio.org/fall-2025-symposium/

With the RECOVER-NEURO clinical trial study results published today, looking forward to these RECOVER pathology studies planned for publication in 2026-2027

Interventions for Cognitive Symptoms in Long COVID This randomized clinical trial investigates if evidence-based rehabilitation strategies improve cognitive symptoms in persons with long COVID.

Unsurprisingly, none of the “brain training interventions” tested in the RECOVER-NEURO Long Covid trial showed efficacy

jamanetwork.com/journals/jam...

AirFanta Personal Wearable Laminar Air Purifier The AirFanta Wear is a personal wearable air purifier. Worn around the neck, it delivers a stream of HEPA-filtered air directly to your breathing zone, creating a personal bubble of clean air. Third-p...

Hey everyone, I'm excited to share that AirFanta Wear is now live on air-fanta.com/products/air...
You'll find a thorough product breakdown and a detailed video I made explaining a lot of things about it. (1/3)

7 basic science discoveries that changed the world Ozempic, MRI machines and flat screen televisions all emerged out of fundamental research decades earlier — the very types of study being slashed by the US government.

A nice article in Nature on how seemingly esoteric, basic science research has had an enormous impact on our lives… highlighting the importance of funding basic research whose practical applications are not yet readily apparent! www.nature.com/articles/d41...

This is cool 🙂

Massachusetts Rebuffs RFK Jr. With Northeast Vaccine Accord
www.msn.com/en-us/health...

Eight states, including Mass., met this week in a step toward public health independence from the federal government - The Boston Globe Northeast states are seeking closer collaboration amid Trump's public health policies.

www.bostonglobe.com/2025/08/22/m...

Depends on what flavor

Oh yes, the traditional delivery method of the potato chip bag, that goes all the way back to the Qing dynasty. Not to mention the OPEN top flap of the red envelope so she could see the cash, that’s totally normal

Well who among us hasn’t tried buying a friend with a hundred something dollars in an open red envelope in a potato chip bag? Come on!

What if everyone had masked up? Analysis of app data has an answer Modelling study based on almost 250,000 positive COVID-19 tests in the United Kingdom shows that universal masking could have cut transmission markedly.

UK: What if everyone had masked up? Analysis of app data has the answer:
"Respirators would have dropped the rate of COVID transmission by an estimated factor of 9, compared with 0.6 for surgical masks. A factor of 9 is enough to put SARS-COV-2 into exponential decay!
www.nature.com/articles/d41...