Measles is a deadly disease. The invention of vaccines to prevent it was a hard-fought triumph of science and goodness. When people choose not to vaccinate their own children, not only are they being foolish and negligent, but they put others at risk.
Just look what we humans can do.
Indeed, Jonathan -- Happy Patriots Day!
Brings back memories of 5 am lineup for parade, watching parents of friends duke it out at the battlegreen reenactment, then pancakes and sausage at the Methodist church across the way. Back then the bike path was train tracks!
Just out - my latest @wsj.com review - a new book offering comprehensive consideration of somatic mutation -> www.wsj.com/tech/biotech... @euanashley.bsky.social @scottgottliebmd.bsky.social @matthewherper.bsky.social
Classic!!!! Remy & Orsillo were my favs.
Most of US doesn't observe Patriot's Day, but it's an amazing tradition here in MA- and a great day for sports, including of course the Boston Marathon (ideal crisp weather for running today) as well as @redsox.com with traditional late morning start; so awesome! @carolynbertozzi.bskyverified.social
Also perhaps of interest (and discussed in interview): @mustafasuleymanai.bsky.social Coming Wave; I also reviewed this in @wsj.com -> www.wsj.com/arts-culture...
This book likely of particular interest to readers who enjoyed @cademetz.bsky.social wonderful account of the history of deep learning, Genius Makers, as I discussed a few years ago in @wsj.com wsj.com/tech/ai/big-... @melaniemitchell.bsky.social @erictopol.bsky.social @nachristakis.bsky.social
This is a fantastically interesting ep of Ground Truth as @erictopol.bsky.social interviews Sebastian Mallaby abt Mallaby's new book The Infinity Machine-intellectual history of AI focused on @demishassabis.bsky.social and Deep Mind. podcasts.apple.com/us/podcast/s... cc @melaniemitchell.bsky.social
Central Park. Never a dull moment.
I’ve discussed topic a few years ago-> www.aei.org/articles/pre...
A fair-skinned red-head person who has discovered he has a predisposition for melanoma only after unleashing AI agents on his genome.
Couldn't listen to their distillation of issues and not think about second half of this classic skit -> youtube.com/watch?v=B9NO... @sarahlongwell25.bsky.social @jvl.bsky.social
My usual w/e routine of exercise+ @thebulwark.com @sarahlongwell25.bsky.social Focus Grp pcast-> amazing ep this wk on Trump v. Pope from POV of Catholic Trump voters (at least that grp was easily the most interesting). Featuing perfect discussant, @jvl.bsky.social podcasts.apple.com/us/podcast/t...
Delightful and well conducted new RCT finds that consumption of coffee was associated with somewhat more daily premature ventricular contractions (154 and 102); more walking (10,646 versus 9,665 daily steps); and less sleep (397 versus 432 minutes of nightly).
www.nejm.org/doi/full/10....
If you've ever had a loved w/pancreatic cancer, you know it's a huge deal for a drug to give people more time. For my latest @opinion.bloomberg.com, wrote about the stunning early results for $RVMD's daraxonrasib, which start to write a new chapter for this cruel disease. (gift link):
Wow - Faraday meets Jacob & Monod!
Moreover, the question of whether to pursue wt loss w GLP-1 or not a key part of Novo strategy discussions based all all the accounts I've seen incl Acquired, "Off the Scales" (my WSJ rev-> wsj.com/arts-culture...), also @erictopol.bsky.social Ground Truth interview w @danieljdrucker.bsky.social
.
Many egs of impt drug effects discovered by "happy accident"-but not everything! GLP-1/wt loss, despite what an otherwise good science writer says in NYT op-ed, NOT an eg. known from earliest days. I discussed in 2024 -> timmermanreport.com/2024/05/the-... @dereklowe.bsky.social @thgoetz.bsky.social
Patients "know what it feels like to be cared for." This.
Lovely final ep of @lisarosenbaum.bsky.social's perceptive @nejm.org NOS pcast series on primary care: podcasts.apple.com/us/podcast/w... Ep has it all for me: agency, SDT, call of stories, limitations of metrics, value of connection & longitudinal relationships; cx of medicine; warmth; love.
🤞
Gorgeous
2/2 This is aligned w need/opportunity for “agency engine” (ideally grounded in discrete accomplishment like exercise can be) I recently described: timmermanreport.com/2026/04/the-...
1/2 Encouraged to see this perspective (articulated as an ambition-and I’d argue a very worthy one) from WHOOP’s AI coach in response to question…
@euanashley.bsky.social @nachristakis.bsky.social
Also #1 in weather
Central Park’s cherry blossoms one chilly spring evening.
Floral print skies. Central Park.
Hall of fame FT correction
Saucer magnolias bloom pink on a blue sky evening in Central Park.
Central Park. Saucer Magnolia Season.