Epigenetic reactivation of the tumor suppressor ZBTB7A by KDM4 inhibition in human acute myeloid leukemia CRISPR screens identify ZBTB7A as a tumor suppressor gene, and therapeutic targeting of KDM4 restores its expression to promote AML differentiation.

Its been a great week for our lab! 🎉 I am excited to share our lab’s second publication!
www.science.org/eprint/W9M5J...

I’m not but my summer undergraduate student Louisa Hagen is :) stop by her poster if you have time! She’s also interested in grad school!

Thank you @jacksonlab.bsky.social for highlighting our recent work!

This work would not be possible with the awesome teamwork from the Wang lab members, and support from @jacksonlab.bsky.social and @leukemiaresearch.bsky.social!

We would also like to thank the amazing Editors at Blood Cancer Discovery @tanyabondar.bsky.social and Abigail Cleveland!

Thrilled to share our lab’s first paper, just out in Blood Cancer Discovery @theaacr.bsky.social!
We uncovered an isoform-specific RUNX1C–BTG2 axis that drives chemoresistance in AML.
aacrjournals.org/bloodcancerd...

Congratulations to our very own, Sadik Karma for being selected by @ash.hematology.org to receive the ASH Graduate Hematology Award (AGHA)! #ASHAwards

Thanks Mike!

Our lab is deeply grateful to @ash.hematology.org for this prestigious Scholar Award and to be in such great company among other outstanding researchers!

Yup exactly!

Not necessary a trick but lenti-X 293T have been boosting our virus titer! Happy to send them to you!