Delta-9-tetrahydrocannabinol and Cannabidiol for Pain: Preclinical and Clinical Models Cannabinoids are increasingly being used to manage pain resulting from a variety of conditions. Both preclinical animal models and human studies have played a crucial role in advancing our knowledge o...

Well our chapter now seems even more relevant. We provide a major review of the empirical data regarding the use of cannabinoids THC and CBD for pain.

link.springer.com/chapter/10.1...

Effects of sex and pre-exposure on Δ9-tetrahydrocannabinol (THC) vapor self-administration in rats - Psychopharmacology Rationale Animal models of cannabinoid self-administration are critical for advancing our understanding of the neurobiology of cannabis use and for developing medications for Cannabis Use Disorder. Us...

New THC vapor self-administration paper with @cassiemoorephd.bsky.social
Published in @PsychopharmEBPS
As part of a special issue honoring my former mentor Klaus Miczek.
Free access using this link:

link.springer.com/article/10.1...

Thank YOU Maggie. It really was!

This was such a great experience. Working with this dream team was the best.

In case you missed it. The terpene alpha-pinene found in cannabis and other natural sources interacts with THC altering its effects. For more on our research follow the John’s Hopkins Cannabis Science Laboratory.

Cannabidiol interactions with Δ-9-tetrahydrocannabinol on antinociception after carrageenan-induced inflammatory pain in male and female rats Cannabis products used for pain typically contain Δ-9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) in varied amounts, but data on the effects o…

New early view paper from our lab led by postdoctoral fellow Bryan Jenkins
@cassiemoorephd.bsky.social‬

Cannabidiol interactions with THC are not what you may expect

www.sciencedirect.com/science/arti...

Great to see the powers that be concerned about adolescent vaping of nicotine and cannabis but how many grants have been funded on these topics in the past several years? #cpdd2025

The proofs for our paper "Prenatal cannabinoid exposure and the developing brain: evidence of lasting consequences in preclinical rodent models" did not include the column with the list of authors cited. The corrected table is here:
authors.elsevier.com/a/1lG0YY3M3l...

Heading to #CPDD25 tomorrow morning and planning my schedule. I always seem to miss something-If you have a talk or poster, please comment so I can add to my list!!

Our new review "Prenatal cannabinoid exposure and the developing brain: evidence of lasting consequences in preclinical rodent models" led by Bryan Jenkins with Lauren Jantzie (not on Bluesky) and @cassiemoorephd.bsky.social FREE access via this link:
authors.elsevier.com/a/1l7fpY3M3l...

I like the title above you and then also noticed you sitting next to the late Emily Jutkiewicz

Great work @drkellydunn.bsky.social and Cecilia Bergeria!

A within-subject, double-blind, placebo-controlled... : PAIN ratory trial was to examine whether cannabidiol (CBD) increases opioid analgesic effects and whether there are corresponding increases in other opioid mediated effects. Healthy participants (N = 31) a...

A new publication showing CBD augmented the analgesic effects of hydromorphone for acute pain, but NOT for chronic pain outcomes in the laboratory.

A within-subject, double-blind, placebo-controlled... : PAIN journals.lww.com/pain/abstrac...

NIH In Your State - United For Medical Research Select a state on the map to see the impact of NIH funding across America.

this website shows you how many jobs NIH funding creates for your state along with the overall economic activity generated
www.unitedformedicalresearch.org/nih-in-your-...

And that 1% unfunded application - ouch

I always seem to miss the #WBCR meeting you go to and vice versa. Looks like a beautiful ski day.

Bioart, courtesy of the NIH. All images are in the public domain and available for download as high-quality SVGs.
bioart.niaid.nih.gov

Thrilled to see this paper published. These data provide strong evidence that physical dependence and withdrawal management is different in the era of illicit #fentanyl versus heroin. We need new strategies to help our patient. Read more about this here: https://buff.ly/4eZ8YqT

Great yo see this data published Kelly. So important to provide empirical evidence that fentanyl dependence is more complex.

try saying lumos and then nox

its just a matter of time before someone does one of these with voice actor humor. “Hello my name Inigo Montoya, prepare to …”

Klaus was a megamentor. So many great students came out of his lab.
The late Jim Winslow (also in the photos) went on to work at NIMH with Tom Insel and contributed so much to our understanding of oxytocin. He was amazing.

Klaus A. Miczek (1945–2024) Nature Neuroscience - Klaus A. Miczek (1945–2024)

Sharing the obituary of my PhD mentor Klaus Miczek by me and his other mentees, @meghaney.bsky.social, JenniferTidey and Jef Vivian. This was was just published in nature neuroscience nam02.safelinks.protection.outlook.com?url=https%3A...

A photo of Brad Marchand yelling above a picture of Moo Deng the baby hippo with her mouth wide open.

Hockey players as Moo Deng, a series.

😡

Minnesota's EagleCam is back — with new birds A new bald eagle nest cam has begun livestreaming from Minnesota. Viewers can watch live as the wild raptor pair builds their nest and raise their young.

A new bald eagle nest cam has begun livestreaming from Minnesota. Viewers can watch live as the wild raptor pair builds their nest and raise their young.

timeless

I think back to many discussions with Emily and others about receptor theory and changes with chronic use and chronic pain. Great to see this!

THIS 👇🏼

More bird need content. here is one of my photos of one of night herons that lives near me. We have about 8-9 nests of these endangered birds living in trees near the water.

A non-science post here. Confession -I am also a bird nerd and these are beautiful