It's a massive pre-IPO marketing event.

I Wrote Research Funding Announcements for NIH for 22 Years. This Year They’ve Published 14 How NIH went from 756 funding announcements to 14 in two years — and what it means for every disease that depends on federal research

open.substack.com/pub/elizabet...
Another thoughtful article from Elizabeth Ginexi on the dramatic reduction in the Notice of Funding Opportunities (NOFO) published by the NIH in 2025 and 2026.

AnkyrinG stands guard,
Master of nodes, silent king—
Cells bend to its will.

Fluorescence Friday - DNA-PAINT imaging of axon initial segment TRIM46 ('cyan') and bIV spectrin ('red') by the incomparable Allison Melton in my laboratory. Just spectacular!

I'll be there soon for a bowl....

Ahhh.. this explains why you never called me.

Rule #12 from the Velominati: // The correct number of bikes to own is n+1.While the minimum number of bikes one should own is three, the correct number is n+1, where n is the number of bikes currently owned.

congratulations Michel! Most deserved!

In the desert of tools to manipulate oligodendrocytes in the brain, we built an OASIS. 🌿 Pun intended. I’m still in awe every time I spot an amazing-looking cell. The beauty of OL and myelin never fails me!
Hope this tool helps more people see it too.

Node of Ranvier

Looks great Paul. I tried tying flies a few years back and had a few reasonable attempts -yours look much better than mine. I'm backpacking the high uintas at the end of August and will fish mostly with mosquitoes.

how were the new wheels?

Congratulations to Dr Gabe Escobedo on his successful thesis defense! An amazing performance! On to even bigger and better things with Eli Lilly.

I review R01 then R21. I ignore whether I am reviewer 1, 2, or 3 and try to imagine I'm reviewer 1 for all of them.

you are the man!

Nice Ride!!!

Another successful NewBee Neuroscience Program in the books! Great time hosting high schoolers from The Village School! Feed your curiosity and live inspired! @bcmhouston.bsky.social

Happy Birthday my friend! You don't look a day over 25. Good luck with the talk and sorry I'm not there to help you celebrate.

Thanks. An unmitigated disaster.

Would you please share where you learned this? Personal communication?thanks.

Great job! Be thankful for spectrin cytoskeletons that let your axons bend each time you pedaled!

Now I have to worry about data AND font triggering you???

The Rasband lab freezer today....

but how do you REALLY feel about this Paul?

What happened to the pursuit of truth? rupress.org/jgp/article/... - Eve Marder, on point...

FIB-SEM dataset visualized with Microscopy Nodes, data from Mocaer et al 2023

Microscopy Nodes is now up on bioRxiv! 🚀

This is a Blender extension that seamlessly integrates and visualizes 3D microscopy data (TIF & @zarr.dev).

High-quality volume rendering for anyone, in both EM and fluorescence, regardless of computational expertise! 🔬

www.biorxiv.org/content/10.1...

yes - just started last week. You should visit with him. He is amazing and knows your work well.

You Can Know Things A blog about science in a world of untrue facts.

Many of you already know about my battle with an autoimmune disease that started shortly after I got COVID in 2022. Here's a summary from a science/health blog aimed at battling disinformation. 🧪😷🧠

Separate from my story, there is a lot of other useful health content!

www.youcanknowthings.com

Oligodendrocyte Myelin Glycoprotein Does Not Influence Node of Ranvier Structure or Assembly Oligodendrocyte myelin glycoprotein (OMgp) is expressed by both neurons and oligodendrocytes in the CNS. It has been implicated in growth cone collapse and neurite outgrowth inhibition by signaling th...

www.jneurosci.org/content/30/4...

And before that there was this one...https://www.jneurosci.org/content/30/43/14476