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Posts by Jon Lim, FRCP PhD

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Fantastic 2 days in San Diego ๐ŸŒด
for the inaugural C8 Early Career Investigators Symposium.

Happy to represent #TeamManchester + connect with an inspiring group ๐ŸŒ.

A reminder that weโ€™re not navigating academia alone - great to hear re: lessons learned & tips for future ๐Ÿค.

@mcrcnews.bsky.social

2 days ago 4 2 0 0
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#ESMOTAT26: Drug development in oncology is increasingly moving towards integrated strategies that consider tumour cells, their microenvironment and anatomical context.
Read the Opinion by Jon Lim, FRCP PhD in the #ESMODailyReporter ๐Ÿ“Œ https://ow.ly/fFUx50YJxOP

5 days ago 2 2 0 0
A collage of images show imaging technologies, stained cells and a mouse in a specially designed research habitat

A collage of images show imaging technologies, stained cells and a mouse in a specially designed research habitat

๐Ÿšจ Open for applications - Director of Scientific Core Facilities & Services!

Shape the strategic future of our core facilities and work with leading experts on cutting-edge cancer discovery and translational research ๐Ÿง‘โ€๐Ÿ”ฌ๐Ÿ”ฌ๐Ÿงช

๐Ÿ’ท ~ยฃ100,000 โฐ 17.5.2026
Apply ๐Ÿ‘‰ www.cruk.manchester.ac.uk/career/mi-26...

1 week ago 4 4 0 0
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Tumour infiltrating lymphocyte (TIL) therapy is here to stay...but toxicity may be the real bottleneck.

Most of it is not the TILs - itโ€™s everything around them. We unpack this in our latest review.

Available #OpenAccess - ๐˜‘ ๐˜๐˜ฎ๐˜ฎ๐˜ถ๐˜ฏ๐˜ฐ๐˜›๐˜ฉ๐˜ฆ๐˜ณ ๐˜Š๐˜ข๐˜ฏ๐˜ค๐˜ฆ๐˜ณ @sitcancer.bsky.social๐Ÿ‘‡
๐Ÿ”— jitc.bmj.com/content/14/4...

1 week ago 4 2 0 0
CRUK MI Director Samra Turaljic superimposed over an image of renal cell carcinoma cells stained with a fluorescenet dye.

CRUK MI Director Samra Turaljic superimposed over an image of renal cell carcinoma cells stained with a fluorescenet dye.

We're thrilled to see our Director, Samra Turajliฤ‡ be awarded the Kidney Cancer Association Pieter De Mulder award for contributions towards the treatment of kidney cancer ๐ŸŽ‰

Samra's research group is investigating how and why kidney cancer evolves to increase the success of treatment strategies ๐Ÿงช

2 weeks ago 10 1 1 0
Research Project Manager | Job advert | Trac

๐Ÿš€ Weโ€™re hiring: ๐—ฅ๐—ฒ๐˜€๐—ฒ๐—ฎ๐—ฟ๐—ฐ๐—ต ๐—ฃ๐—ฟ๐—ผ๐—ท๐—ฒ๐—ฐ๐˜ ๐— ๐—ฎ๐—ป๐—ฎ๐—ด๐—ฒ๐—ฟ ๐—ถ๐—ป ๐—œ๐—บ๐—บ๐˜‚๐—ป๐—ผ-๐—ข๐—ป๐—ฐ๐—ผ๐—น๐—ผ๐—ด๐˜†

An exciting ๐Ÿ†• role which sits at the heart of a highly collaborative & ambitious ecosystem spanning the Manchester Immuno-Oncology Network (MION) + the Advanced Immunotherapy and Cell Therapy (AICT) programme.

๐Ÿ“ฉ Deadline 9th April 2026.

3 weeks ago 2 1 0 0
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Cross-presentation of dead cell-associated antigens shapes the neoantigenic landscape of tumor immunity - Nature Immunology Here the authors show DNGR-1 expressed by cDC1s promotes CD8โบ T cell priming to cytoskeletal neoantigens from dying tumor cells, thereby shaping cancer immune visibility and tumor evolution through im...

Next, master of dendritic cells Caetano has an update on dead cell recognition in the context of tumor immunity:

We knew DC use exposed actin to gobble up dead cells. Here they show if you tether a model tumor antigen to actin, you get better anti-tumor immunity. Neat!!!

doi.org/10.1038/s415...

2 months ago 2 1 1 0
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Advances in cell therapy for solid tumours: European perspective and future directions Cell therapy has revolutionised the landscape of cancer treatment, with therapies such as Chimeric Antigen Receptor T cells (CAR-T cells), showing remarkable efficacy in haematological malignancies, a...

Cell therapy for solid tumours is advancing rapidly, but translation into patient benefit will depend on continued collaboration ๐ŸŒ.

๐Ÿ’ก Delighted to see this work come to fruition - thanks to all co-authors, for this thoughtful & collaborative effort.

@haanenjohn.bsky.social

#OpenAccess ๐Ÿ‘‡

1 month ago 3 1 0 1
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New Research: TRNA Modification Triggers Anti-tumour Immunity | Cancer Research UK Manchester Institute New research has uncovered an unexpected way to stimulate the immune system against cancer: by subtly disrupting how tumour cells manufacture their proteins.

Exciting new research from our Group Leader @sylvaindelaunay.bsky.social and Pierre Close at @universitedeliege.bsky.social shows how modifying a tRNA can alter the immune profile of #melanoma - exposing it to the #ImmuneSystem

Read the full story here:

www.cruk.manchester.ac.uk/news/new-res...

1 month ago 6 3 0 0
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We have three exciting opportunities for you to join us for a fully-funded 4-year #PhD project here in #Manchester starting in October 2026

Find full details of all the projects on our website: www.cruk.manchester.ac.uk/phd-student-...

Applications close 3rd April 2026

1 month ago 5 5 0 0
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Tumour-infiltrating lymphocyte therapy in melanoma: ready for prime time? - British Journal of Cancer British Journal of Cancer - Tumour-infiltrating lymphocyte therapy in melanoma: ready for prime time?

Just in time for our national TIL Therapy Summit in Manchester! We are pleased to share our perspective on the future of tumour-infiltrating lymphocyte (TIL) therapy.

Available open access via @springernature.com:
www.nature.com/articles/s41...

1 month ago 1 0 0 0

Fantastic inaugural national TIL Therapy Summit in Manchester with a stellar faculty โญ.

Great to welcome colleagues from across the UK & Europe for a day full of insightful discussions on the current landscape + future of TIL therapy.

@mcrcnews.bsky.social

1 month ago 3 3 1 0
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Do you have an impactful research idea?
One that could improve care or advance science?

Apply for the ESMO Leadership & Career Development Award, offering protected research time, leadership & communication training by 3 May 26 .

๐Ÿ”—https://ow.ly/Gicm50YqcbZ

#Oncology #ESMOYOC

1 month ago 4 5 1 0

The Crick Postdoctoral Clinical Fellowship has been one of the most pivotal steps in my development as a clinical academic.

The environment, mentorship, infrastructure, and scientific ambition at @crick.ac.uk are truly unparalleled.

Strongly recommended! Deadline: 30th April ๐Ÿ‘‡

1 month ago 0 0 0 0
Emerging Leaders | Emerging Leaders - British Journal of Cancer BJCโ€™s Emerging Leaders collection recognises stand-out early-to-mid career researchers, clinicians, and educators within the field of oncology.

Grateful to ๐˜‰๐˜ณ ๐˜‘ ๐˜Š๐˜ข๐˜ฏ๐˜ค๐˜ฆ๐˜ณ for the kind feature in their ๐—˜๐—บ๐—ฒ๐—ฟ๐—ด๐—ถ๐—ป๐—ด ๐—Ÿ๐—ฒ๐—ฎ๐—ฑ๐—ฒ๐—ฟ๐˜€ collection. Thank you to the editors for the nomination ๐Ÿ™.

Like many things, this really reflects teamwork & collaboration with many generous colleagues. Our perspective on TIL therapy in melanoma is now out #OpenAccess ๐Ÿ‘‡

1 month ago 4 1 1 0
Man in a dark blue patterned shirt leaning on a window ledge inside a bright, modern corridor with large windows.

Man in a dark blue patterned shirt leaning on a window ledge inside a bright, modern corridor with large windows.

Professor Ludwig Dubois joins the MCRC & @manchester.ac.uk @fbmh-uom.bsky.social
as Chair in Experimental & Translational Radiobiology.

Heโ€™ll spearhead research into proton beam therapy & FLASH treatments to improve patient outcomes.

Read more: https://ow.ly/1k5g50YkUEn

1 month ago 2 1 0 0
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Tumour-infiltrating lymphocyte therapy in melanoma: ready for prime time? - British Journal of Cancer British Journal of Cancer - Tumour-infiltrating lymphocyte therapy in melanoma: ready for prime time?

Our new perspective just out in ๐˜‰๐˜ณ๐˜ช ๐˜‘ ๐˜Š๐˜ข๐˜ฏ๐˜ค๐˜ฆ๐˜ณ on TIL therapy in melanoma.

As TIL move closer to real-world use, the ๐˜ฉ๐˜ฐ๐˜ธ matters as much as the ๐˜ธ๐˜ฉ๐˜ฆ๐˜ต๐˜ฉ๐˜ฆ๐˜ณ. We reflect on the near future & the practical challenges of moving from trials to routine care.

Keen to hear thoughts/experiences from others๐Ÿ‘‡

2 months ago 2 1 0 0

Come and join us at the ESMO Preceptorship on CUP! @worldcupalliance.bsky.social spread the word!

2 months ago 7 2 0 0
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๐ŸŽ“ New PhD Opportunity

An exciting PhD opportunity at the Cancer Research UK Manchester Centre, supporting the next generation of leaders in cancer research.

๐Ÿ“… Deadline: Friday 3 April
๐Ÿ”— For further information & to apply: ow.ly/ZWYs50Y7vHR

@uom-dcs.bsky.social
@manchester.ac.uk

2 months ago 2 1 0 0
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๐Ÿ‘‰...cutting-edge science, clinical insights & discussions re: real-world implementation of TIL therapy.

Featuring keynote speakers:
Inge Marie Svane ๐Ÿ‡ฉ๐Ÿ‡ฐ & Sebastian Klobuch ๐Ÿ‡ณ๐Ÿ‡ฑ.

@sklobuch.bsky.social
@debrajosephs.bsky.social
@turajliclab.bsky.social
@beckilee.bsky.social

2 months ago 3 3 0 0
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Unlocking TIL Therapy: A New Era for Melanoma Care in the UK TIL (Tumour-Infiltrating Lymphocyte) therapy is a transformative, cell-based immunotherapy approach now entering clinical practice for melanoma. This national summit brings together UK and internation...

๐Ÿ“ฃ Final agenda confirmed - only 5 weeks to go!

Join us on ๐Ÿญ๐Ÿญ ๐— ๐—ฎ๐—ฟ๐—ฐ๐—ต ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฒ in Manchester ๐Ÿ for our inaugural TIL Summit: Unlocking TIL Therapy โ€“ A New Era for Melanoma Care in the UK.

Kindly sponsored by The Christie Charity.

Space limited - so don't miss out! For further information & to register:

2 months ago 5 4 1 0
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The beginning of an international partnership between The Christie and the National Cancer Institute of Ukraine The Christie Institute for Cancer Education has welcomed international colleagues from the National Cancer Institute of Ukraine (UNCI) as part of a new education partnership focused on bilateral shari...

One of the projects Iโ€™m most proud of since returning to Manchester.

In awe of the resilience of our Ukrainian colleagues delivering cancer care under extraordinary circumstances, and grateful for the generosity of #TeamManchester colleagues in sharing best practice.

๐Ÿ‡ฌ๐Ÿ‡ง ๐Ÿค ๐Ÿ‡บ๐Ÿ‡ฆ

Find out more ๐Ÿ‘‡

2 months ago 2 1 0 0
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New Journal for ImmunoTherapy of Cancer review: Steroid-sparing strategies for managing immune-related adverse events jitc.bmj.com/content/14/1...

2 months ago 2 1 0 0
lab to life

lab to life

Exciting conference alert!

sites.manchester.ac.uk/from-lab-to-...

Fantastic speakers includingย Chris Marine, Christian Blank

Melanoma evolution
Local microenvironment of melanoma
Melanoma-host interactions
Precision immunotherapy
Emerging therapeutics
Clinical trials and real-world data

2 months ago 5 5 0 0

๐Ÿ”— For further details (deadline 3 June 2026):
www.esmo.org/meeting-cale...

2 months ago 1 0 0 1
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๐Ÿ†• New on the ESMO events calendar for 2026!

Mark your calendar for the ๐—˜๐—ฆ๐— ๐—ข ๐—ฃ๐—ฟ๐—ฒ๐—ฐ๐—ฒ๐—ฝ๐˜๐—ผ๐—ฟ๐˜€๐—ต๐—ถ๐—ฝ ๐—ผ๐—ป ๐—ง๐˜‚๐—บ๐—ผ๐˜‚๐—ฟ-๐—”๐—ด๐—ป๐—ผ๐˜€๐˜๐—ถ๐—ฐ ๐—–๐—ฎ๐—ป๐—ฐ๐—ฒ๐—ฟ๐˜€ ๐—ฎ๐—ป๐—ฑ ๐—–๐—ฎ๐—ป๐—ฐ๐—ฒ๐—ฟ ๐—ผ๐—ณ ๐—จ๐—ป๐—ธ๐—ป๐—ผ๐˜„๐—ป ๐—ฃ๐—ฟ๐—ถ๐—บ๐—ฎ๐—ฟ๐˜† (๐—–๐—จ๐—ฃ) in Zurich: 18-19 September 2026.

Chaired by the fantastic @oncocook.bsky.social & @benwestphalen.bsky.social.

@myesmo.bsky.social

2 months ago 3 0 1 1

This is one of the projects Iโ€™m most proud of since coming back to (re-)join #TeamManchester faculty. Delighted to welcome and host our Medical Oncology colleagues from UNCI, Kyiv at The Christie.

๐Ÿ‡บ๐Ÿ‡ฆ ๐Ÿค ๐Ÿ‡ฌ๐Ÿ‡ง

3 months ago 5 2 0 0

Youโ€™re such an inspiration, Adam! Keep going ๐Ÿ™Œ.

3 months ago 1 0 1 0
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๐Ÿš€ Kicking off the new year with our next #ChristieFellowship session!

How do we communicate science well - to patients, the public, and on social media?

Join us for an interactive session on ๐—ฃ๐˜‚๐—ฏ๐—น๐—ถ๐—ฐ ๐—–๐—ผ๐—บ๐—บ๐˜‚๐—ป๐—ถ๐—ฐ๐—ฎ๐˜๐—ถ๐—ผ๐—ป with Prof @achoud72.bsky.social.

@christieinstitute.bsky.social
@mcrcnews.bsky.social

3 months ago 5 3 0 0

Thanks to @acir-org.bsky.social for highlighting our article!

3 months ago 9 2 0 0