✨ April is #GraduateStudentAppreciation Month!

🏐 Highlighted here, Emma Andraka. Mentored by Daniela Schiller & @brianmsweis.bsky.social, Emma is developing a cross-species task for elucidating decision-making processes & neurophysiology underlying social interactions in rodents & humans. AMAZING!

Want a dataset to test ideas on neural basis of decision making or how areas interact as we make choices? Check out our data published today @rudebecklab.bsky.social. >16,000 single neurons from 22 anatomically confirmed areas in macaques performing a decision task. www.nature.com/articles/s41...

Addressing degeneracy in rodent studies of cognition In order to relate neural dynamics to cognitive computations, it is critical to determine whether subjects are employing behavioral strategies that ac…

Excited to share our recent review, which highlights algorithmic and implementational degeneracy in studies of cognition: www.sciencedirect.com/science/arti...

Thank you @drnancypadilla.bsky.social for hosting me! I hope this can be a helpful resource for students considering if the MD/PhD path is right for them!

Thank you @drnancypadilla.bsky.social for hosting me! I hope this can be a helpful resource for students considering if the MD/PhD path is right for them!

Congrats!

Acetylcholine demixes heterogeneous dopamine signals for learning and moving Nature Neuroscience - Jang et al. measured dopamine and acetylcholine release in the striatum of rats performing a decision-making task and found that the relative timing of cholinergic and...

Thrilled to share our new paper, which shows that the relative timing of cholinergic and dopamine release dynamically gates whether dopamine acts as an RPE for in vivo plasticity and reinforcement learning. www.nature.com/articles/s41...

🚨The Sweis Lab for Translational Neuroeconomics at Mount Sinai is searching for a postdoctoral research fellow! If you or someone you know is searching for a position, please share!

📄 📌Link to job flyer here:
tinyurl.com/3vapfpn5

🧠 🐁 🔬🏙️🌆🧪🧬💊🧫💡🏥
@sinaibrain.bsky.social @mountsinai.bsky.social

Very cool! Quick naive question - I’d imagine these effects could not be accounted for / are not driven by simpler changes in imaging due to a disturbance in the liquid compartments affecting the sensor optics themselves, changes in the z plane, etc?

Pokémon turns 30 — how the fictional pocket monsters shaped science The Japanese media sensation has inspired generations of researchers in fields as diverse as evolution, biodiversity and research integrity.

For Pokémon’s 30th anniversary, Nature spoke to scientists from around the world about how their work has been shaped by playing Pokémon games, watching animated TV series and films and trading cards in school playgrounds. 🧪

Congratulations to our 2026 Scholars! This year’s projects span molecules to circuits to behavior and reflect the highly collaborative environment that defines neuroscience at Mount Sinai. Sincere thanks to the donors whose support makes this type of curiosity-driven science possible.

The KM Lab is hiring!
We're looking for both a new technician (makes a great post-bac like experience) and a post-doc.

Come do fun science. Come join an amazing community.

Learn more:
sites.google.com/site/krookma...

Postdoctoral Research Fellow in Social Decision Neuroscience at University of Birmingham Explore an exciting academic career as a Postdoctoral Research Fellow in Social Decision Neuroscience. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

We are recruiting! Postdoctoral research fellow at www.sdn-lab.org, studying the computational & neural basis of social decision-making. Birmingham is a fantastic & affordable place to live, with one of the youngest populations in Europe & over 600 parks. Please share!
www.jobs.ac.uk/job/DQO275/p...

Congrats all!

Neuroscience has a species problem If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.

If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle rather than an afterthought, writes @suthanalab.bsky.social.

#neuroskyence

www.thetransmitter.org/animal-model...

Really important insight from @suthanalab.bsky.social. There seems to be lots of general agreement about the importance for cross-species analysis. But, in practice and in the trenches - there's a real divide on how to do it and how to implement it. Appreciate these conversations being raised!

Congrats!!

How does neuronal gene expression evolve over time in response to experience? CytoTape will help us find out - a major milestone for neuroscience, providing new ways to study memory & aging 🧠

Congrats to the whole team! Looking forward to our continued collaboration on this work 🎉

🧠📢 New preprint alert

Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵

#neuroskyence #compneurosky

(1/6) We have a new paper out in #eNeuro!

How does the brain’s reward processing change across social contexts? We mapped brain activity (cFos) & found that social context reshapes how reward circuits are coordinated🐭🏆

Read more: www.eneuro.org/content/12/1...

Characterizing neuronal population geometry with AI equation discovery The visual cortex contains millions of neurons, whose combined activity forms a population code representing visual stimuli. There is, however, a discrepancy between our understanding of this code at ...

1. New preprint resolving a conundrum in systems neuroscience with an AI scientist, and humans Reilly Tilbury, Dabin Kwon, @haydari.bsky.social, @jacobmratliff.bsky.social, @bio-emergent.bsky.social, @carandinilab.net, @kevinjmiller.bsky.social, @neurokim.bsky.social
www.biorxiv.org/content/10.1...

🚨 Reminder: Applications for #OptoGRC2026 are now OPEN!

Don’t miss your chance to join an incredible week of science, discovery, and connection with the brightest minds in optogenetics 💡🧠

Apply now for the best chance of acceptance: www.grc.org/optogenetic-...

NOT TO MISS! In @mountsinainyc.bsky.social's 2025 issue of Science & Medicine magazine, Dean @ericjnestler.bsky.social discusses his vision for Icahn Mount Sinai, and how his distinguished academic career & research expertise have prepared him. 👉 scienceandmedicine.mountsinai.org/article/2025...

It’s giving Dr. T.J. Eckleburg

A Special Congratulations to @ericjnestler.bsky.social on receiving the 2025 Synapsy Prize. This prestigious award celebrates lifelong dedication to translating fundamental neuroscience discoveries into tangible clinical advancements in mental health. Learn More 👉 www.eurekalert.org/news-release...

Stop by our posters tomorrow afternoon at #SFN25!! #sfn2025 @sfn.org #neuroscience

Large-scale cellular-resolution read/write of activity enables discovery of cell types defined by complex circuit properties The complexity of the mammalian brain’s vast population of interconnected neurons poses a formidable challenge to elucidate its underlying mechanisms of coordination and computation. A key step forwar...

✨ New preprint ✨ What if we could watch AND control thousands of individual neurons in behaving mice—with stable access over months? 🧠⚡ Our work introduces transgenic all-optical tools that make this possible - and a resulting surprising discovery! 🔭💡
www.biorxiv.org/content/10.1... 1/13 🧵

…plus a ZZZEST for experiment 🤓

Our Behavioural Brain Research special issue on Ultrasonic Communication in Rodents is growing, rapidly – and actually a lot faster than I manage to post about it. Nine new manuscripts got accepted since my last post. Quite impressive work. Check it out:
www.sciencedirect.com/special-issu...