The next iteration of O-MAP targeting genomic loci is now at eLife!!
DNA O-MAP enables proximity labeling at specific DNA loci took a ton of work from many lab members and collaborators, so it's really exciting to wrap up this paper with @oligopain.bsky.social!
elifesciences.org/articles/102...
We are delighted to announce that Paola Picotti has been awarded the Otto Naegeli prize for biomedical research!
otto-naegeli-preis.ch
Excellent visualization of the true distance between the Earth and our moon: #artemis #AGoodPlace
Source: www.reddit.com/r/BeAmazed/s...
To better understand the ubiquitin-proteasome system, Suzanne Elsasser, Dan Finley, and the Human Proteostasis Consortium have systematically surveyed its components:
www.biorxiv.org/content/10.6...
I would encourage you to check out this valuable resource! @harvardcellbio.bsky.social
This morning’s course on studying protein-protein interactions is well on its way at #USHUPO2026! I just wrapped up my talk on AP-MS, and now Lan Huang is talking about crosslinking MS. This afternoon Ling Hao will be talking about proximity labeling as well. @us-hupo.org
Applications are now open for @olgavitek.bsky.social 's May Intitute on computation and statistics for mass spectrometry and proteomics at @northeasternu.bsky.social !
--> computationalproteomics.khoury.northeastern.edu
Unexpected Kid Math Question: how many digits of pi do you need to look at to find the series “67”?
Answer: 100
If you’ve been wondering, you’re welcome!
Trombone next to a music stand
Christmas concert season is here! Tonight I played a concert with the New England Brass Band.
I am looking for a PostDoc to join my group at Genentech to drive the development of proteomics technologies to fuel target and therapeutic discovery and development. Check out the link below!
careers.gene.com/us/en/job/20...
Congratulations to Bill Noble on receiving the 2026 Gil Omenn Computational Proteomics Award from US HUPO!
us-hupo.org/Computationa...
Congratulations to Mike MacCoss on receiving the Donald F. Hunt Distinguished Contribution in Proteomics Award from US HUPO!
us-hupo.org/Distinguishe...
If you’re at #HUPO2025, be sure to stop by my poster and learn about the latest developments in the BioPlex project!
#HUPO2025 I Our CTDP poster was very well-received! Thank you all for coming! It is free to join CTDP! If you are interested in learning more about #topdownproteomics, please join our talks tomorrow 😀❤️ @proteoforms.bsky.social @nlkproteomics.bsky.social @edhuttlin.bsky.social
Kudos to the organizers (Jennifer Geddes-McAlister, @mlaval6.bsky.social, Marie Brunet) for arranging snow to coincide with the start of HUPO 2025 in Toronto!
I’m at the airport a and ready to fly to Toronto for this year’s HUPO conference. I’m looking forward to talking about AP-MS tips and tricks at tomorrow’s pre-conference workshop on protein-protein interactions and sharing our latest BioPlex results in a poster on Wednesday!
We are ready for Halloween!
Check out this thread from @haopengxiao.bsky.social on his recent paper! I’m happy I was able to help out on what has turned out to be a really cool story.
Hey @haopengxiao.bsky.social - it’s great to see you on BlueSky!
Could your new account be a sign you might have something cool to announce soon???? ;-)
Excited to share a new preprint from the lab. We show that PTMs like phosphorylation & glycosylation dynamically reshape proteome-wide ligandability in cells, including proteins like KRAS. Great collaboration with the Huang Lab, @forlilab.bsky.social and BMS. www.biorxiv.org/content/10.1...
And although it’s important to acknowledge specific COI, like industry-sponsored research, that isn’t the whole story. In truth, we all share a universal COI, which is that our career advancement - the next degree, job, grant, promotion, etc. - depends on producing “good” results.
Yeah - that’s really my point. COI discussions tend to focus on private funding, but I think from the standpoint of undue external pressure to produce results, public funding isn’t all that different.
Thoughts from our own Tom Rapoport on the role of basic science in curing disease. magazine.hms.harvard.edu/articles/rev...
than it is already.
It’s also worth noting that public funding can present its own issues. When it’s very competitive to get and keep public funding, that also creates pressure on researchers to produce impressive results. With paylines at the NIH potentially dropping to ~5% in the coming years, this will be even worse
If your concern is with private funding of science in general, I suppose there’s room for debate. But as federal funds for science are cut in the US, private funding will be increasingly important. For me, now that Trump has cut all federal funding to Harvard, private funding is keeping us afloat.
I’m not sure I understand what you’re seeking here either. If the issue is transparency, each of the PI’s above has been open about their collaborations with industry - enough so that they’re easily recognizable from the logos you display and your joke works.
Not really an overstatement to say that the test of a free society is whether or not comedians can make fun of the country's leader on TV without repurcussions.
If you’re at #ASMS2025, stop by the Protein-protein and Protein-ligand Interactions section this afternoon and hear how we are leveraging our BioPlex network and AlphaFold structural models for drug discovery!
If you're going to #ASMS2025, don't miss these Gygi lab presentations! You'll learn about TMT, chemoproteomics, GoDig for targeted proteomics, leveraging BioPlex interactions for drug discovery, new instrumentation, and more! @amandalsmythers.bsky.social @asms.org @harvardcellbio.bsky.social
#ASMS2025 is fast approaching, and I'm looking forward to catching up with friends and seeing a lot of great mass spectrometry research. If you’re there, check out my Tuesday talk (TOE 3:10 PM) to learn how BioPlex is enhancing drug discovery!
