I am deeply grateful to @ASCBiology and truly humbled by this recognition of my research through the Postdoctoral Porter Prize for Research Excellence. Congratulations to all the awardees!

🚨Our latest work on selfish centromeres is published @currentbiology.bsky.social 🐭🧬We found that the spindle checkpoint contributes to non-Mendelian segregation! Huge congrats to our lab manager, Zaak Walton, who led the project🎉

Free link:
authors.elsevier.com/a/1lQzN3QW8S...

Happy to share our latest work on the structure and assembly of holocentric kinetochores! Huge thanks to Ines for a very fruitful collaboration, Claudio for all the support, and congratulations to Christine and all co-authors!

www.biorxiv.org/content/10.1...

A versatile cohesion manipulation system reveals CENP-A dysfunction accelerates female reproductive age-related egg aneuploidy. Female reproductive aging is accompanied by a dramatic rise in the incidence of egg aneuploidy. Premature loss of chromosome cohesion proteins and untimely separation of chromosomes is thought to unde...

Some good news during these difficult times. Please check out our new preprint. We built a new tool to probe the origins of high oocyte aneuploidy rates at advanced female reproductive ages. This NIH funded work was led by a fantastic postdoc in the lab, Jiyeon Leem. www.biorxiv.org/content/10.1...

If you have been affected by the fires in LA, or are concerned about your ability to keep precious Drosophila strains going during the latest funding crisis, we will host your strains as a backup. Please email me.

Please amplify. If you are also able to host fly strains, add your name as well.

New preprint! Eric Smith and Jimmy Ly reveal a beautiful example of repurposing of a molecular machine. RNase P + RNase MRP share 9 subunits and yet are functionally very different. We find key new subunits that act as specificity factors to distinguish MRP.

www.biorxiv.org/content/10.1...

EMBO meiosis: Registration deadline Feb 15!📣

Experimental horizontal transfer of phage-derived genes to Drosophila confers innate immunity to parasitoids Metazoan parasites have played a major role in shaping innate immunity in animals. Insect hosts and parasitoid wasps are excellent models for illumina…

Excited to share the major work of my dissertation, out now in @currentbiology.bsky.social! We use Drosophila genetics to dissect the evolution of phage-derived toxins that were horizontally transferred to insects and now function as potent anti-parasitoid defenses (1/n): tinyurl.com/2k9ypyxr

Join us this morning at #cellbio2024 for an exciting line up of meiosis talks!