So happy to see Mark recognised for his incredible work. Over a ~40 year career he and his group discovered ECF sigma factors, characterised many key developmental regulators of the Streptomyces lifecycle, and identified new mechanisms of bacterial gene regulation, antibiotic action and resistance.
Millington, J. W., Lopez, J. A., Sajjadian, A. M., Scheffler, R. J., DeFelice, B. C., Ludington, W. B., Good, B. H., O'Brien, L. E., Huang, K. C. (2025). Gut microbe-derived lactic acid optimizes host energy metabolism during starvation. bioRxiv, www.biorxiv.org/content/10.1...
💣 At 3am, the nukes were coming... Or so Zbigniew Brzezinski was told.
Edward Luce revisits one of the Cold War’s most surreal nights — and the legacy of Carter’s underrated strategist.
Read in the @ObserverUK: Meet the President’s Main Man by John Bew observer.co.uk/culture/book...
it’s a real testament to the intellectual traditions of these centuries-old institutions, folding to authoritarian pressure like paper in a storm and kneeling to naked financial extortion
A personal message from 2022 chemistry laureate Carolyn Bertozzi to all young researchers on why to aspire to a career in science: ”I would want to share with them how a life in science is incredibly rewarding. It is rewarding because it is creative. You are discovering knowledge and gifting that to humanity for all of posterity. Once you learn something no one can take that away. It is not an object. It is an intellectual currency that will be shared throughout the generations. And you created that. It has a permanence that ironically a physical object doesn’t have. You can paint a painting, but eventually it will fade. But knowledge doesn’t fade. Knowledge stays with us forever and it becomes the foundation for the next generations.”
A motivating quote from @carolynbertozzi.bskyverified.social:
“…You are discovering knowledge and gifting that to humanity for all of posterity. Once you learn something no one can take that away. It is not an object. It is an intellectual currency that will be shared throughout the generations…”
“The word ‘Dimore’ in Italian means dwelling but conjures up images of old villas clinging to their aristocratic origins. It lends the name a sense of nostalgia. I think it’s our DNA” – Britt Moran
No, no, no; a million times no. just stop this. DNA is a polydeoxyribonucleotide.
This part of the Tufts declaration somehow warms my heart the most: a full-throated defense of Rümeysa Ötürk's op-ed criticizing the Tufts president, signed by the Tufts president! This is how it's supposed to be!
Since April, we have been busy curating pathways using GO-CAM pathway modelling. So far, 466 proteins (33 pathways) have been modelled. We have modelled signalling pathways, metabolic pathways, and other processes. The full list is here: www.pombase.org/documentatio..., and will increase weekly!
you and Martin Taylor were first by a long way.
totally bonkers; was it published to show the degree of imbecility amongst the incoming administration?
