Insights from three decades of BRCA1/2 modeling in mice - Nature Genetics This Perspective highlights the insights into the biology of BRCA1/2 afforded by mouse models and patient-derived tumor xenografts and emphasizes their value in addressing unresolved questions and pre...

🐭 In vivo veritas 🐭

Now out in Nature Genetics: @josjonkers.bsky.social and I describe currently available mouse models of BRCA1/2 and their roles in understanding BRCA1/2 biology, particularly in normal development, tumor suppression and therapy response.

www.nature.com/articles/s41...