Cooking up some beautiful images this #FluorescenceFriday

Imaging drug localisation by fluorescence lifetime imaging... Incredible insights that would only otherwise be achievable by mass spec imaging! #FluorescenceFriday

Late entry to #FluorescenceFriday, melanoma spheroids showing an interesting branching phenotype. Membrane in cyan, nuclei in magenta.

Spooky!

Looking at metabolic status in ovarian cancer spheroids by imaging autofluorescence. Intensity image left, Fluorescence lifetime image right 💡 #FluorescenceFriday

It's been a beautiful sunny week, so here's another London rooftop view this time @crick.ac.uk

It's a beautiful sunny day in London @imperialcollegeldn.bsky.social
Spring is on its way 🌿

Stunning 😍🧠

A cool technological advancement I saw this week is from Roche, sequencing by expansion. Combining the speed and sensitivity of nanopore methods with clever sample prep to increase resolution. Very accessible and informative video here:
sequencing.roche.com/global/en/ar...

Very cool! Best of luck with it.

Thanks Lucien!
It was a plate I was trying out from 4Dcell, they're V-shaped with ULA coating at the coverslip. Details here if useful www.4dcell.com/cell-culture...

I hope you're doing okay now.

Awesome! Have you tried looking at these samples with a lightsheet method? Large FOV deep images sound useful if you can do this in tissue slices etc!

Thanks Rachael!

Thanks so much! Yes, we're trying to combine emerging technologies in 3D cell culture and imaging to do just that. There's a long way to go but it's a great field to be in and motivation comes very easily knowing the clinical need!

New to BlueSky, let's start off with a #FluorescenceFriday
Here are some ovarian cancer patient derived spheroids growing in an array ammeanbale to high content imaging.