Thanks, Michalis. You have been a patient and inspiring coordinator of this project.

Congratulations, Luis! So happy for you.

Félicitations à Luis BEZARES-CALDERON @biodev-vlfr.bsky.social lauréat d'une bourse « Research Grant » de Human Frontier Science Program Organization @hfspo.bsky.social pour le projet Tracing the Evolutionary History of Sensory Perception via TPR Channels

www.insb.cnrs.fr/fr/cnrsinfo/...

Dr. Laurent Formery presents in front of an audience in a seminar room. On a screen, a slide with a phylogenetic tree of animals is visible.

Fantastic talk this morning by @laurentformery.bsky.social @biom-banyuls.bsky.social 🙌 Laurent presented his work on cellular reprogramming and symmetry during sea cucumber metamorphosis ✨ Beautiful images and lots of exciting discussions - thank you for visiting us in #SunnyBergen!

BMP signaling-dependent dorsal-to-ventral gradient of PAX3/7 transcriptional activity revealed by the P34::tk::LacZ reporter. Left: expression patterns of neural progenitor (NP) and interneuron (IN) TF markers in the developing spinal cord. Right: Immunostaining for β-galactosidase (β-gal; red/grey), GFP (blue/grey) and either OLIG3 (green/grey) or pSMAD1/5/9 (green/grey) on transverse sections of E9.0 (bottom) and E9.5 (top) P34::tk::LacZ; Pax3+/GFP spinal cords at brachial level. Black and white panels show magnified views of the boxed region.

How do pleiotropic TFs generate organized diversity in developing tissues? @spinalorga.bsky.social shows that PAX3 & PAX7 organize #SpinalCord by acting as both repressors & pioneer activators, regulated by #morphogens to ensure precise neural subtype specification @plosbiology.org 🧪 plos.io/4qumsla

What are these?

You are looking at embryos of a sea squirt. Each of the 'soap bubbles' is a living cell, about a fourtieth of a millimetre in size. The outlines of the cells are visible thanks to fluorescent markers identified by Hitoyoshi Yasuo @hitoyas.bsky.social

see doi.org/10.1101/2024... 🧵