Mr Wilkieβs bill proposes changes to the social security law relating to oversight of automated decision-making, requiring manual oversight of such decisions at Services Australia. region.com.au/all-private-...
Colonel Chestbridge holding a sword, jonesing for a drink "And of course as always, Kill Hitler"
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List of the names of the 231 Palestinian, 3 Lebanese and 2 Israeli journalists killed covering Israel's genocide of Gaza since 7 Oct 2023
Of course, journalists in LA should not be targeted by police with rubber bullets. But let's not ignore the real issue of journalist safety
Immediately after Israel comes 2nd in Eurovision, BBC News comes on, and the first story is footage of Israel bombing Gaza and killing children
Someone please tell me how this is real life?
π free Palestine π΅πΈ
#Eurovision #Politics #Palestine #Israhell
Unfortunately due to grant funding, full scholarships aren't available for her intake. She's been an absolute star and was so determined to get into this, but is now left without a scholarship. Every contribution helps her get closer to a programme that changed my life π
My friend Belinda has been graciously accepted into the Erasmus Mundus Infectious Disease and One Health Master's programme (www.infectious-diseases-one-health.eu) that I had the luck to be a part of π
Unfortunately due to grant funding, full scholarships aren't available for her intake. She's been an absolute star and was so determined to get into this, but is now left without a scholarship. Every contribution helps her get closer to a programme that changed my life π
My friend Belinda has been graciously accepted into the Erasmus Mundus Infectious Disease and One Health Master's programme (www.infectious-diseases-one-health.eu) that I had the luck to be a part of π
SAAP-148 is protective against colonisation by #AMR bacteria in skin and lung tissue models and synergises with the repurposed antibiotic halicin
doi.org/10.1093/jaca...
@prlennard.bsky.social #JACAMRNews #IDSky
π TL;DR: New paper, new antibiotic combinations, new doctor π For all the juicy details, check out the full study here: doi.org/10.1093/jaca... #OpenAccess #ScienceTwitter #MedicalResearch #InfectiousDiseases #OneHealth #Microbiology @bsacandjac.bsky.social
π This work doesnβt happen in a vacuum: thanks to my principal supervisor Julia Dorin, and all my friends and colleagues at the LUMC, both in the Infectious Diseases department and the Leiden PulmoScience Lab
π€ Together, this work adds to the growing evidence base for advancing SAAP-148, other HDPs, and halicin for antibacterial therapy against AMR strains, both in combination and sequential therapy #AntibioticAlternatives
π‘ When assessing the combination of preventative SAAP-148 and post-infection halicin treatment in these cultures, I also found that SAAP-148 and halicin only acted synergistically in skin but not in lung tissue (still beneficial though!) #CombinationTherapy #SequentialTreatment
π¬ I expanded on this: instead using SAAP-148 as a preventative against AMR bacteria, applied in both HSEs and lung tissue cultures (PBECs). SAAP-148's activity was limited in PBECs against AMR bacteria, while active in HSEs due to the peptide being retained in cells
β However, our team showed that SAAP-148 was effective against AMR bacteria in the dish, and also when infecting skin cultures (HSEs). Also, combining SAAP-148 with halicin (a repurposed antibacterial) was synergistic against AMR bacteria. Read it: www.mdpi.com/2079-6382/11... #SynergisticTherapy
π Few studies specifically investigate synergy between host defence peptides (HDPs), like SAAP-148, and conventional antibiotics. Even then, many donβt clarify this effects between agents, or assess them in more dimensional models. Reviewed here: www.mdpi.com/2079-6382/12...
Happy to announce another published thesis chapter, now available in JAC-Antimicrobial Resistance! πIt features work from 3D cultures of skin and lung tissue as models of infection with #AMR bacteria, and therapy with the antimicrobial peptide SAAP-148 #AntimicrobialResistance @jac-amr.bsky.social
π TL;DR: New paper, new antibiotic combinations, new doctor π For all the juicy details, check out the full study here: doi.org/10.1093/jaca... #OpenAccess #ScienceTwitter #MedicalResearch #InfectiousDiseases #OneHealth #Microbiology @bsacandjac.bsky.social
π This work doesnβt happen in a vacuum: thanks to my principal supervisor Julia Dorin, and all my friends and colleagues at the LUMC, both in the Infectious Diseases department and the Leiden PulmoScience Lab
π€ Together, this work adds to the growing evidence base for advancing SAAP-148, other HDPs, and halicin for antibacterial therapy against AMR strains, both in combination and sequential therapy #AntibioticAlternatives
π‘ When assessing the combination of preventative SAAP-148 and post-infection halicin treatment in these cultures, I also found that SAAP-148 and halicin only acted synergistically in skin but not in lung tissue (still beneficial though!) #CombinationTherapy #SequentialTreatment
π¬ I expanded on this: instead using SAAP-148 as a preventative against AMR bacteria, applied in both HSEs and lung tissue cultures (PBECs). SAAP-148's activity was limited in PBECs against AMR bacteria, while active in HSEs due to the peptide being retained in cells
β However, our team showed that SAAP-148 was effective against AMR bacteria in the dish, and also when infecting skin cultures (HSEs). Also, combining SAAP-148 with halicin (a repurposed antibacterial) was synergistic against AMR bacteria. Read it: www.mdpi.com/2079-6382/11... #SynergisticTherapy
π Few studies specifically investigate synergy between host defence peptides (HDPs), like SAAP-148, and conventional antibiotics. Even then, many donβt clarify this effects between agents, or assess them in more dimensional models. Reviewed here: www.mdpi.com/2079-6382/12...
Happy to announce another published thesis chapter, now available in JAC-Antimicrobial Resistance! πIt features work from 3D cultures of skin and lung tissue as models of infection with #AMR bacteria, and therapy with the antimicrobial peptide SAAP-148 #AntimicrobialResistance @jac-amr.bsky.social
π¦ AMR poses a global threat. SAAP-148 reduced colonization of AMR bacteria in skin models. It boosted HDPs & IL-8. Synergistic effects with halicin were seen in skin, not in bronchial cells.
#idsky
