Was a pleasure to chair this session at an outstanding #AACRevol25 meeting

Program Program details for AACR Special Conference in Cancer Research Cancer Evolution

Ben Raphael, Niko Beerenwinkel, Chris Venditti, and George Butler will discuss "Computational Approaches to Cancer Evolution" in a plenary session at the AACR Special Conference on Cancer Evolution (December 4-6; Albuquerque). Learn more:
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#AACRevol25 @braphael.bsky.social

A graph homomorphism approach for unraveling histories of metastatic cancers and viral outbreaks under evolutionary constraints - Nature Communications Human diseases may evolve by migration or spread, but understanding these complex processes is challenging. Here, the authors leverage graph homomorphisms to reconstruct trees describing histories of ...

Check out this new publication by IICD member @braphael.bsky.social and team in @natcomms.nature.com: Graph Homomorphism Approach for Unraveling Histories of Metastatic Cancers and Viral Outbreaks under Evolutionary Constraints

www.nature.com/articles/s41...

Categorization of 34 computational methods to detect spatially variable genes from spatially resolved transcriptomics data - Nature Communications In spatial transcriptomics data analysis, identifying spatially variable genes (SVGs) is crucial for understanding tissue organization and function. The authors categorize 34 computational methods for...

How do we detect spatially variable genes (SVGs) in spatial transcriptomics?

In our Nature Communications review, we categorize 34 computational methods into three categories:
✅ Overall SVGs
✅ Cell-type-specific SVGs
✅ Spatial-domain-marker SVGs

www.nature.com/articles/s41...

NIH ban on renewing senior scientists adds to assaults on its in-house research Policy follows firings of tenure-track scientists and suspension of training programs

Friends, I am at a loss of words for how devastating it would be to lose the entire intramural #NIH program. Some of the biggest medical and scientific breakthroughs have come from scientists in the NIH Intramural program. #SaveTheNIH 🧬🧪 🖥️ 🧠

www.science.org/content/arti...

RECOMB-CCB workshop is combing to Seoul, chaired by @shenhui1986.bsky.social and Andrew Roth! Submissions are open for papers and abstracts

Impressions from Ascona Workshop: Spatial and temporal statistical modeling in molecular biology

www.huber.embl.de/group/events...

A latent variable model for evaluating mutual exclusivity and co-occurrence between driver mutations in cancer bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Yes, the preprint is here: www.biorxiv.org/content/10.1...

Now: Keynote by Peter Park: A new mechanism for oncogene amplification. #RECOMB2024 💻🧬🧪