Exciting new research in advanced melanoma shows sequencing T-cells can help predict and monitor response to adoptive cell transfer, a treatment using a patient’s own immune cells to attack cancer. @uhnresearch.ca @uhn.ca @oicr.on.ca
doi.org/10.1186/s130...
Posts by Pugh Lab
🌟New Resource article
Read about the pancancer landscape of cancer-specific cell-free DNA methylation and fragmentomic features from plasma samples from 1,294 patients
✒️Yong Zeng, @matlupien.bsky.social, @pughlab.bsky.social, Housheng Hansen He & colleagues
www.nature.com/articles/s43...
Massive team-science effort across @pmresearch-uhn.bsky.social @uhnresearch.ca @uhn.ca @oicr.on.ca and collaborators (incl. TrevorPugh & Hansen He labs; lead author Yong Zeng).
www.nature.com/articles/s43...
🍁🔬MOHCCN Clinician Scientist Awards 2026 Launch🍁🔬
The MOHCCN Clinician Scientist Awards provide funding to young investigators looking to conduct high-quality, clinically-related research in precision oncology.
Letter of Intent due: January 22, 2026
Learn more: tinyurl.com/dn774xa5
Today is a great day for cancer research in Canada and, more importantly, for the health of all Canadians! We sincerely thank the Government of Canada for its ongoing commitment to improve the lives of Canadians diagnosed with cancer through the work of the Network.
Full statement ▶️ bit.ly/4oSuFhp
🎉 Congratulations to LTRI alumna Dr. Mary Brunkow on receiving the 2025 Nobel Prize in Physiology or Medicine for her groundbreaking immune system research.
Read the story: www.sinaihealth.ca/news/ltri-al...
Image of Toronto
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
www.nature.com/naturecareer...
Please repost!
Mark your calendar with #CGCAnnual2026—we look forward to seeing you in Houston next year!
#CGCAnnual2026 #genomics #cancer #research #genetics #clinicaltesting #bioinformatics #cytogenetics #molecular
After a quarter of a century, the UCSC Genome Browser remains an essential tool for navigating the genome and understanding its structure, function and clinical impact
https://go.nature.com/40wPxkB
For those of you who may not have known him, Dr. Atul Butte, a pioneer in informatics, was the winner of the 2024 Morris F. Collen award, a pinnacle achievement in our field, as part of his storied career.
His passing is a major loss to us all.
RIP Dr. Butte
#MedSky
Excited to share our first lab paper, now published in Developmental Cell @cellpress.bsky.social !
🧠 How do glioblastoma (GBM) cells invade the brain, and what enables them to spread so effectively?
Cell therapy has revolutionized cancer treatment. Now, its potential is expanding far beyond.
Join us for the launch of the Centre for Immunology to Immunotherapy at UHN to explore the future of cell therapy:
events.myconferencesuite.com/Ci2iSymposiu...
New evidence @nejm.org today that age-related clonal hematopoiesis (CHIP) has a driver role in evolution of solid cancers
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
An illustrated diagram of the biologic features of extrachromosomal DNAs
A recent study shows how extrachromosomal DNA contributes to tumor heterogeneity and may drive cancer progression. Learn more: nej.md/42jfYdH
#MedSky #Oncology #Genetics
The Allan Slaight Breakthrough Forum brought together 60+ scientists from Princess Margaret Cancer Centre, Krembil Research Institute, and CAMH to explore the links between cancer, neuroscience, & mental health. Looking forward to the exciting discoveries ahead!
www.uhnresearch.ca/news/advanci...
Excellent Op-Ed by Peter Zandstra on improving 🇨🇦 science at a time when 🇺🇸 is throttling their golden goose. Instead of bespoke, targeted & ultimately short term solutions limited to a few people, build a deep, more attractive ecosysyem. The best will thrive. www.theglobeandmail.com/gift/46242ee...
We're excited to join Bluesky! Follow us for the latest news about cBioPortal.
First newsletter of 2025! Read to get the latest news and all the details on GSoC 2025 projects and application process #cBioPortal #newsletter #gsoc2025 www.linkedin.com/pulse/welcom...
🇨🇦 Fast-track your computational biology/bioinformatics career in cancer research! 🇨🇦
The Lupien Lab is looking to recruit a Postdoctoral Fellow in computational biology/bioinformatics ready for a challenge.
Apply now: www.nature.com/naturecareer...
#REVIEW
Vallot, Lupien and Lasine describe how epigenomic heterogeneity generates dynamic reservoirs of tumour cell states, which can be leveraged in the design of novel therapies.
📖 👉 https://bit.ly/40PCQ
Rates of #cancer in #young #adults have risen dramatically in recent years - as discussed in this article..
We urgently need to invest in #research 🧪 on early-onset cancers to understand - why?
www.theguardian.com/science/2025...
Come be my boss!
We're looking for a new Program Head for the Molecular Medicine Program at the Hospital for Sick Children.
Toronto, Canada
(the deadline has been extended from Jan 31)
Please Re-post.
jobs.sciencecareers.org/job/667223/p...
Indeed, there are a number of open positions for early career investigators in Toronto. It's a great city in a great country to pursue impactful science.
Seems like a perfect day to consider continuing your research career in beautiful Canada! Recruiting an ECR in cancer research, a week left to apply.
Absolutely thrilled to see the next next-generation sequencer arrive on our doorstep. Looking forward to affordable deep dives into cell-free genomes. Will we be able to reconstruct cancer genomes from blood without a biopsy, even for early cancers? We think so!