And this is a bit of a trope... but I think that robots and self-driving will allow people to remain independent much longer than is currently possible, smoothing the demographic cliff.

When the paper you think for sure is a hallucination is in fact a real reference

This really showcases the promise of using mouse sys neuro. to understand human clinical treatments, congratulations! Still struck by the 150 s long calcium events.

Delighted to share our discoveries about one of the brain's neurotransmitter systems:
www.biorxiv.org/content/10.6...

Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1

Pupil-linked arousal heterogeneously modulates cell-type–specific sensory processing Two-photon imaging and pupillometry reveal how arousal modulates excitatory neuron subtypes in auditory cortex.

Excited to share a new paper from our lab, just in time for Easter, where we characterize how arousal modulates different excitatory cell-types in the auditory cortex! www.science.org/doi/10.1126/...

Very cool!

Or its a classic limitless situation: the fruit fly only uses 0.1% of its brain at any time.

Seriously though, nice work!

Nice work from the Williamson lab!

OSV!

This is really cool work!

Must be their von Economo neurons...

Congrats! Super excited to where this line of work takes you!

Congratulations all! This is awesome work.

Call it #ExplainableAI or just making sense of complexity. We establish a direct link between DNNs fit to #AuditoryCortex and more intuitive subspace models from the 2000s. Congrats @jeremewingert.bsky.social @satyaparida.bsky.social & Sam Norman-Haignere! #NeuroAI #SensoryNeuroscience rdcu.be/e5gLY

Will probably go the way of BYD imho.

Do you think this is all engineering/regulatory speed or is there novel science in here that we should be paying attention to?

In praise of artifice - Nature Neuroscience Nature Neuroscience - In praise of artifice

Provocative: www.nature.com/articles/nn1...

I feel the same way about anesthesia in sensory neuroscience... probably just as many confounds of awake recordings as in anesthetized, just different problems. But less clear than it might seem at first pass about which one is "natural"

Smart! have been having a lot of fun trying out new analyses on various datasets this way.

New world inspiring old world inspiring new world. Did not appreciate Thomas Jefferson's scientific inclinations till I learned how he sent a Moose across the Atlantic to convince French scientists about the size of North American land mammals.

Not only code, the bar for accessing poorly documented/idiosyncratic open datasets has also dropped because LLMs can parse all the unfun stuff to port them into a useable format.

Related, has anyone figured out how to get their institution to pay for Claude code access/bill to grant? Mine won't.

The hyperlinks in the final pdf it creates are okay, right? 😱

New preprint from the lab! 🚀
We find that hippocampal OLM interneurons provide a circuit-level inhibitory feedback signal that dynamically controls when and where behavioral timescale synaptic plasticity can occur.
Feedback welcome!

Congrats Megan!!

Canonical cortical architecture supports the emergence of noise-invariant auditory representations Neurons in the auditory system must represent behaviorally relevant sounds in the presence of background noise (BN) to support noise-invariant perception and behavior. Although primary auditory cortex...

Just in time for Xmas! Check out some new work from my lab looking at noise-invariant representations in excitatory cell-types! Congrats to Tommy Suarez-Omedas! www.biorxiv.org/content/10.6...

Moravec's Paradox and the Robot Olympics By fine-tuning our latest model, we were able to solve a series of very difficult manipulation challenge tasks.

The most impressive robotics video I've seen in a while: www.pi.website/blog/olympics. I regret that my peak dish-doing/clothes folding years have come before everyone has one of these in their house.

A figure from our preprint showing ABR data as a line plot for sounds from the left and right at different sound levels.

1/4 New preprint! We designed an open-source system for auditory brainstem response (ABR), a research & clinical auditory test. Costs $400 to build (vs $10K to buy a proprietary one) and works great! All open-source if you want to make one for your lab or classroom. www.biorxiv.org/content/10.6...

An almost 20th anniversary, whole-brain edition of Sakata and @kenneth-harris.bsky.social's great work on sequences in auditory cortex from 2008, congrats!

Btw, I still have open positions available for post-docs. Esp if you’re interested in applying modern dimensionality reduction approaches to in vivo Ca2+ imaging or ephys datasets. Please get in touch pierre.apostolides@umich.edu

Our lab is hoping to hire a long-term lab manager / research associate to help with admin tasks and neuroscience experiments (3-year minimum commitment). bilh.wd1.myworkdayjobs.com/External/job...

A real pleasure and honor interviewing @neurozoe.bsky.social. Check out her story!