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Posts by Yi-Wei Chang

Congratulations to Melanie Ohi for this very well-deserved recognition!

4 months ago 2 0 0 0
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...and big thanks to @jiwasa.bsky.social for making this amazing video to illustrate the strand-sliding mechanism!

11 months ago 30 9 1 2
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Molecular basis of influenza ribonucleoprotein complex assembly and processive RNA synthesis Influenza viruses replicate and transcribe their genome in the context of a conserved ribonucleoprotein (RNP) complex. By integrating cryo–electron microscopy single-particle analysis and cryo–electro...

Excited to share our new @science.org paper! Led by postdocs Ruchao Peng and Xin Xu, we used cryo-EM/ET to reveal the influenza ribonucleoprotein complex structure and its strand-sliding mechanism for RNA synthesis, paving the way for new antivirals.
www.science.org/doi/10.1126/...

11 months ago 122 56 7 3

Thrilled to share our @elife.bsky.social paper "Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages" by 1st author Dr. @marisaegan.bsky.social (@cambupenn.bsky.social alum, now faculty @swarthmorecollege.bsky.social)! elifesciences.org/articles/90107 🧵(1/n)

1 year ago 97 26 10 3

Exciting update on the CryoET Data Portal! A new annotation set from Mart Last & team is now live. They’ve doubled available annotations with >1,800 tomograms of Chlamydomonas reinhardtii which now have almost fully dense labels, and all can be visualized in the browser using Neuroglancer.

1 year ago 41 15 1 0

Thrilled to share that our work with the Ben Black Lab, led by a co-mentored star MD/PhD student Katie Kixmoeller, now is formally published! We used cryo-ET to study kinetochore features in human mitotic chromosomes. 🧬🔬❄️

1 year ago 9 0 0 0
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🦟🌍 Join us for the 21st edition of #EMBLMalaria as we strengthen partnerships, share insights, and drive innovations to combat malaria's toll and advance global health.

📅 20 – 22 May 2025
📍 EMBL Heidelberg and Virtual
📝 Submit abstract by 25 Feb

👉🏻 s.embl.org/bmp25-01-bl

#malaria #epidemiology

1 year ago 10 8 0 2